Zobrazeno 1 - 10
of 104
pro vyhledávání: '"W J O'Reilly"'
Autor:
S. W. Homans, W. J. O'reilly, Peter J. F. Henderson, Paul J. R. Spooner, Anthony Watts, Nicholas G. Rutherford
The weak binding of sugar substrates fails to induce any quantifiable physical changes in the L-fucose-H+ symport protein, FucP, from Escherichia coli, and this protein lacks any strongly binding ligands for competitive binding assays. Access to subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be5fd14b9c5eef31635b041eae62d657
https://ora.ox.ac.uk/objects/uuid:172676df-e815-473e-acc9-2ba1415bd02f
https://ora.ox.ac.uk/objects/uuid:172676df-e815-473e-acc9-2ba1415bd02f
Publikováno v:
Clinical Pharmacokinetics. 4:310-319
The pharmacokinetics of N1-acetylsulphamethoxazole and N4-acetylsulphamethoxazole in man are described. N1-Acetylsulphamethoxazole is deacetylated to sulphamethoxazole and acetylated to N4-acetylsulphamethoxazole. N4-Acetylsulphamethoxazole is excret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e16e6f0fe77b73eb826f01b17b526e2
https://doi.org/10.2165/00003088-197904040-00004
https://doi.org/10.2165/00003088-197904040-00004
Publikováno v:
Clinical Pharmacokinetics. 5:274-294
The pharmacokinetics of sulphamethizole, sulphamethoxazole, sulphadiazine, sulphapyridine and sulphadimidine have been studied in man. Renal clearance values of the metabolite N4-acetylsulphonamide are 6 to 20 times higher than those of the correspon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e1c95c05b2eb73826aef57ab5a5bfe
https://doi.org/10.2165/00003088-198005030-00006
https://doi.org/10.2165/00003088-198005030-00006
Autor:
B. G. Priestly, W. J. O'reilly
Publikováno v:
Journal of Pharmacy and Pharmacology. 18:41-45
The kinetics of biliary excretion of four dyes, amaranth, geranine, lissamine and dechlorolissamine have been examined in the rat. The protein binding of each dye to blood and liver in vitro was examined, and a correlation found between excretion rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aa6310711825cebccb38cebdfeeb468
https://doi.org/10.1111/j.2042-7158.1966.tb07769.x
https://doi.org/10.1111/j.2042-7158.1966.tb07769.x
Publikováno v:
British Journal of Pharmacology. 43:167-179
Summary 1 A one-compartment pharmacokinetic model was developed in which a drug underwent two successive metabolical reactions (for example, metabolism followed by conjugation) and free drug and both metabolites were excreted. 2 Techniques were descr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4531dad8dd597a04c65b80ab309396a8
https://doi.org/10.1111/j.1476-5381.1971.tb07166.x
https://doi.org/10.1111/j.1476-5381.1971.tb07166.x
Publikováno v:
Medical Journal of Australia. 2:590-592
In children, the blood level of phenytoin was found to be significantly higher when 100 mg capsules rather than 100 mg tablets were administered. When, on the other hand, 30 mg capsules and tablets were compared; the situation was reversed; tablets p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5931b9948b15ff59f740e14cae40d255
https://doi.org/10.5694/j.1326-5377.1975.tb106113.x
https://doi.org/10.5694/j.1326-5377.1975.tb106113.x
Autor:
Lloyd Sansom, Roy G. Beran, Philip E. Stanley, C. J. Doecke, W. J. O'Reilly, Graham J. Schapel, Phillip A. Reece, R. H. C. Rischbieth
Publikováno v:
European journal of clinical pharmacology. 17(1)
Pharmacokinetic analysis of the plasma valproic acid concentration-time course, following a single oral dose (600 mg) of sodium valproate, was performed in 20 epileptic patients as an aid to the prediction of a proper chronic dosage regimen. A simple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89cbe72c89215170b75e0a273f65917e
https://pubmed.ncbi.nlm.nih.gov/6768573
https://pubmed.ncbi.nlm.nih.gov/6768573
Autor:
W. J. O’Reilly
Publikováno v:
Volume 1A: General.
Continuing worldwide escalation of fuel prices has provided the impetus for the design and manufacture of power conversion equipment of higher efficiency. A high-effectiveness regenerator design, based on adaptions of the criteria used in the aerospa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8316f0e02d45e58f53b3b94e0399f818
https://doi.org/10.1115/78-gt-78
https://doi.org/10.1115/78-gt-78
Publikováno v:
The Medical journal of Australia. 2(15)
A cross-over study was conducted to compare the plasma phenytoin levels produced by different phenytoin preparations available in Australia. The preparations were found not to be equivalent, a liquid suspension product producing higher levels compare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b167c1a51cd4b834f0bf13f1581aba1
https://pubmed.ncbi.nlm.nih.gov/1105111
https://pubmed.ncbi.nlm.nih.gov/1105111
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 201(3)
Rats, with and without bile duct ligation (BDL), were injected with hexobarbital (i.p. and i.v.) and blood concentrations measured as a function of time. Analysis of these curves using a single-compartment model showed that BDL altered hexobarbital p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e8b2d8af8db8217b9f0122ea03596305
https://pubmed.ncbi.nlm.nih.gov/864592
https://pubmed.ncbi.nlm.nih.gov/864592