Zobrazeno 1 - 10
of 21
pro vyhledávání: '"W J Longmore"'
Autor:
W J Longmore, J T Mourning
Publikováno v:
Journal of Lipid Research, Vol 18, Iss 3, Pp 309-313 (1977)
An investigation of the effect of change of total CO2 concentration from 7 to 43 mM at pH 7.35 in the medium perfusing isolated rat lungs on [U-14C]glucose incorporation into lung phospholipids has been carried out. The incorporation of [U-14C]glucos
Externí odkaz:
https://doaj.org/article/0dd13555a38d487393732fad3c98ec5b
Autor:
Leonard D. Hudson, T J Gregory, G Z Cai, A J Gold, M A Moxley, K P Steinberg, P Newton, B R Mitchell, R D Hite, Robert M. Smith, Roger G. Spragg, W J Longmore, T M Hyers, C Crim, J E Gadek
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 155:1309-1315
Lung surfactant is deficient in patients with acute respiratory distress syndrome (ARDS). We performed a randomized, prospective, controlled, open-label clinical study of administration of a bovine surfactant to patients with ARDS to obtain prelimina
Autor:
Richard A. Pierce, M. A. Moxley, Gail L. Griffin, Robert M. Senior, W. J. Longmore, M. S. Mudd
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 14:239-247
Although the composition of the subepithelial basement membrane of the alveolar septum has been studied in detail, there is relatively little information about which cells produce it. We examined intact rat lung and isolated rat alveolar type II cell
Autor:
A A Fowler rd, T M Hyers, W J Longmore, Jeffrey A. Whitsett, C Crim, M A Moxley, T J Gregory, L D Hudson, R J Maunder, Carly R. Reed
Publikováno v:
Journal of Clinical Investigation. 88:1976-1981
Acute Respiratory Distress Syndrome (ARDS) is characterized by lung injury and damage to the alveolar type II cells. This study sought to determine if endogenous surfactant is altered in ARDS. Bronchoalveolar lavage was performed in patients at-risk
Expression of laminin alpha3, alpha4, and alpha5 chains by alveolar epithelial cells and fibroblasts
Autor:
R A, Pierce, G L, Griffin, M S, Mudd, M A, Moxley, W J, Longmore, J R, Sanes, J H, Miner, R M, Senior
Publikováno v:
American journal of respiratory cell and molecular biology. 19(2)
Laminins are principal components of basement membranes. Eleven laminin isoforms are known, each a heterotrimer composed of polypeptide chains designated alpha, beta, and gamma. Five alpha chains have been identified to date: alpha1, alpha2, alpha3,
Autor:
P L, Ballard, L M, Nogee, M F, Beers, R A, Ballard, B C, Planer, L, Polk, D E, deMello, M A, Moxley, W J, Longmore
Publikováno v:
Pediatrics. 96(6)
To evaluate components of pulmonary surfactant and identify mutations in the surfactant protein B gene (SP-B) of a term infant with severe respiratory distress and chronic lung disease. PATIENT AND TESTING: Respiratory distress developed in an infant
Publikováno v:
Journal of Applied Physiology. 66:1846-1851
Pulmonary surfactant replacement has previously been shown to be effective in the human neonatal respiratory distress syndrome. The value of surfactant replacement in models of acute lung injury other than quantitative surfactant deficiency states is
Autor:
R F Fricke, W J Longmore
Publikováno v:
Journal of Biological Chemistry. 254:5092-5098
Autor:
L A Brown, W J Longmore
Publikováno v:
Journal of Biological Chemistry. 256:66-72
The purpose of this study is to define the hormonal regulation of pulmonary surfactant secretion in two models, the isolated perfused rat lung and the isolated alveolar type II cell in culture. In the perfused lung, both cholinergic and adrenergic st
Publikováno v:
Federation proceedings. 41(12)
Quantitatively accurate studies of macromolecule and lipid synthesis in lung and other tissues by using radioactive substrates require detailed knowledge of the specific radioactivity of the appropriate pool of precursor molecules serving the synthet