Výsledky vyhledávání - "W J J, Krauwinkel"

Effect of age on the pharmacokinetics of solifenacin in men and women

Autor: M E J Taekema-Roelvink, R A Smulders, H Mulder, W J J Krauwinkel, P J Swart

Publikováno v: Int. Journal of Clinical Pharmacology and Therapeutics. 43:227-238

Objective: The pharmacokinetics of solifenacin succinate (YM905; Vesicare®), a new, bladder-selective, muscarinic receptor antagonist for the treatment of overactive bladder in young/middle-aged and elderly subjects werecompared. Material: Solifenac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcacc13496bdaff298c981c4147a5e46
https://doi.org/10.5414/cpp43227

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The gastrointestinal passage and release of beclomethasone dipropionate from oral delivery systems in ileostomy volunteers

Autor: J. Burggraaf, H. C. Schoemaker, A. D. Van Haarst, Adam F. Cohen, W. J. J. Krauwinkel, P. Fockens

Publikováno v: British Journal of Clinical Pharmacology. 46:207-214

Aims To study the delivery of 15 mg beclomethasone 17,21-dipropionate (BDP) to the distal part of the small bowel for three oral sustained-release formulations (I-III) and a reference capsule in volunteer ileostomists, and to compare these findings w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5188d8f15bc1aca87e984aee67e7ef91
https://doi.org/10.1046/j.1365-2125.1998.00782.x

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No pharmacokinetic interaction between ipragliflozin and sitagliptin, pioglitazone, or glimepiride in healthy subjects

Autor: R A, Smulders, W, Zhang, S A, Veltkamp, J, van Dijk, W J J, Krauwinkel, J, Keirns, T, Kadokura

Publikováno v: Diabetes, obesitymetabolism. 14(10)

To investigate the effect of ipragliflozin on the pharmacokinetics of sitagliptin, pioglitazone or glimepiride and vice versa in healthy subjects.Three trials with an open-label, randomized, two-way crossover design were conducted in healthy subjects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c52219bc91d6f6b9ebcc0e76f5be373a
https://pubmed.ncbi.nlm.nih.gov/22587345

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Pharmacokinetics of tamsulosin in subjects with normal and varying degrees of impaired renal function: an open-label single-dose and multiple-dose study

Autor: W. J. J. Krauwinkel, G. T. Dorner, V. Fabrizii, P. Leufkens, Michael Wolzt, Hans-Georg Eichler, G. Zanaschka

Publikováno v: European journal of clinical pharmacology. 54(4)

Objective: This study was performed to estimate whether the pharmacokinetics and safety of tamsulosin, an α1A-adrenoceptor antagonist for the treatment of symptomatic benign prostatic hyperplasia (BPH), are influenced by impaired renal function. Met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfb2cabe5e3537046f8a5395e9c9de23
https://pubmed.ncbi.nlm.nih.gov/9696967

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