Zobrazeno 1 - 10
of 58
pro vyhledávání: '"W J Harper"'
Autor:
Dan Gibson, Roman Sirota, Benjamin W. J. Harper, Janice R. Aldrich-Wright, Emanuele Petruzzella, Aviva Friedman-Ezra
Publikováno v:
ChemMedChem. 12:510-519
The discrepancy between the in vitro cytotoxic results and the in vivo performance of Pt56MeSS prompted us to look into its interactions and those of its PtIV derivatives with human serum (HS), human serum albumin (HSA), lipoproteins, and serum-suppl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf228008b260ca989f2ea0cec5f89d9d
https://doi.org/10.1002/cmdc.201700092
https://doi.org/10.1002/cmdc.201700092
Publikováno v:
Food Preservation Technology ISBN: 9781566767835
Pulsed Electric Fields in Food Processing: Fundamental Aspects and Applications
Pulsed Electric Fields in Food Processing: Fundamental Aspects and Applications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba3a132b27c569332840fffb2fe7d3bd
https://doi.org/10.1201/9780429133459-14
https://doi.org/10.1201/9780429133459-14
Publikováno v:
Journal of Inorganic Biochemistry. 163:95-102
Platinum(II) complexes have demonstrated considerable success in the treatment of cancer, but severe toxic side effects drive the search for new complexes with increased tumour selectivity and better efficacy. A critical concept that has to be consid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc0b41fcb77d747679b6eea02065f41
https://doi.org/10.1016/j.jinorgbio.2016.06.004
https://doi.org/10.1016/j.jinorgbio.2016.06.004
Autor:
Benjamin W. J. Harper, Emanuele Petruzzella, Roman Sirota, Valentina Gandin, Fernanda Fabiola Faccioli, Janice R. Aldrich-Wright, Dan Gibson
Publikováno v:
Dalton transactions (Cambridge, England : 2003). 46(21)
This report describes the synthesis, characterization and biological activity of a series of platinum(iv) derivatives of [Pt(1S,2S-DACH)(5,6-dimethyl-1,10-phenanthroline)] (Pt56MeSS) with non-bioactive, lipophilic and bioactive axial ligands. In an a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36e13225dac060283a681c533e7558f1
https://pubmed.ncbi.nlm.nih.gov/28513693
https://pubmed.ncbi.nlm.nih.gov/28513693
Autor:
Benjamin W J, Harper, Aviva, Friedman-Ezra, Roman, Sirota, Emanuele, Petruzzella, Janice R, Aldrich-Wright, Dan, Gibson
Publikováno v:
ChemMedChem. 12(7)
The discrepancy between the in vitro cytotoxic results and the in vivo performance of Pt56MeSS prompted us to look into its interactions and those of its Pt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf1c4c2b6483d493c6b0ad99b946abc0
https://pubmed.ncbi.nlm.nih.gov/28206707
https://pubmed.ncbi.nlm.nih.gov/28206707
Autor:
Madhura Manohar, K. Benjamin Garbutcheon-Singh, Benjamin W. J. Harper, Nikita Orkey, Anwen M. Krause-Heuer, Maxine P. Grant, Janice R. Aldrich-Wright
Publikováno v:
Current Topics in Medicinal Chemistry. 11:521-542
With an ageing baby-boomer population in the Western World, cancer is becoming a significant cause of death. The prevalence of cancer and all associated costs, both in human and financial terms, drives the search for new therapeutic drugs and treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ac1e42fc3b96f7333618dab4b994f0e
https://doi.org/10.2174/156802611794785226
https://doi.org/10.2174/156802611794785226
Autor:
Janice R. Aldrich-Wright, Benjamin W. J. Harper, Oscar Mendoza, Leticia Cubo, Ramon Vilar, Dale L. Ang
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 22(7)
Four dinuclear terpyridineplatinum(II) (Pt-terpy) complexes were investigated for interactions with G-quadruplex DNA (QDNA) and duplex DNA (dsDNA) by synchrotron radiation circular dichroism (SRCD), fluorescent intercalator displacement (FID) assays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b0159bd75e66ffae128606d478c542
https://pubmed.ncbi.nlm.nih.gov/26670391
https://pubmed.ncbi.nlm.nih.gov/26670391
Publikováno v:
Dalton transactions (Cambridge, England : 2003). 44(1)
Dinuclear (2,2':6',2''-terpyridine)platinum(II) (PtTerpy) complexes were synthesised by tethering either thiol or pyridine based linkers. All intermediates and resulting complexes were characterised using a combination of (1)H and (195)Pt NMR, two-di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbb9a8a66bccd8bb8d7bd2eb8f4ccb5a
https://pubmed.ncbi.nlm.nih.gov/25407567
https://pubmed.ncbi.nlm.nih.gov/25407567
Publikováno v:
Journal of Zhejiang University-SCIENCE A. 2:204-208
Cheese slurries, made from fresh Swiss cheese curd, were treated at 345 or 550 MPa for 10 or 30 minutes in an isostatic press at 25°C. The slurries were ripened at 30 °C for 0,3 and 5 days. The growths of coliforms, yeasts and molds, starter bacter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2eb8e14c3914e372b9070addb8ddd8c
https://doi.org/10.1631/jzus.2001.0204
https://doi.org/10.1631/jzus.2001.0204
Autor:
Benjamin W. J. Harper, K. Benjamin Garbutcheon-Singh, Janice R. Aldrich-Wright, Simon J. Myers
Publikováno v:
Metallomics : integrated biometal science. 6(1)
With current chemotherapeutic treatment regimes often limited by adverse side effects, the synergistic combination of complexes with anticancer activity appears to offer a promising strategy for effective cancer treatment. This work investigates the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1395cd4f5ffa03e0ceccd87463422b8f
https://pubmed.ncbi.nlm.nih.gov/24084749
https://pubmed.ncbi.nlm.nih.gov/24084749