Zobrazeno 1 - 9
of 9
pro vyhledávání: '"W J Checovich"'
Publikováno v:
Arteriosclerosis and Thrombosis: A Journal of Vascular Biology. 11:351-361
We previously described the hypercholesterolemia of pigs with defined apolipoprotein B (apo B) alleles associated with reduced binding of low density lipoprotein (LDL) to its receptor in vitro and slow clearance from the circulation in vivo. The incr
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 283(2)
Omeprazole 5-hydroxylation and sulfoxidation activities were determined in liver microsomes of different humans whose levels of individual forms of cytochrome P450 (P450 or CYP) varied. Correlation coefficients between omeprazole 5-hydroxylation acti
Publikováno v:
The Journal of Cell Biology
Lysophosphatidic acid is a product of activated platelets and has diverse actions on cells. We have characterized the effect of lysophosphatidic acid on cell-mediated binding and assembly of fibronectin, an extracellular matrix protein. Serum made fr
Autor:
Deane F. Mosher, W J Checovich
Publikováno v:
Arteriosclerosis and thrombosis : a journal of vascular biology. 13(11)
1-Oleoyl lysophosphatidic acid (LPA) enhanced binding of 125I-labeled fibronectin by cultured MG-63 osteosarcoma cells and human fibroblasts in monolayer cultures up to threefold over control levels. For osteosarcoma cells, LPA was minimally active a
Publikováno v:
Arteriosclerosis and thrombosis : a journal of vascular biology. 12(10)
We have identified very low density (VLDL) and low density (LDL) lipoproteins as blood plasma components that enhance the binding and deposition of fibronectin into the extracellular matrices of cultured MG-63 osteosarcoma cells and human fibroblasts
Publikováno v:
Molecular and cellular biochemistry. 113(2)
We previously described a strain of spontaneously hypercholesterolemic pigs carrying an apo-B allele termed Lpb5. Lpb5 pigs are heterogeneous with respect to the severity of their hypercholesterolemia. We have termed Lpb5 pigs with severe hypercholes
Publikováno v:
Journal of Biological Chemistry. 263:15467-15473
We previously identified a defect in the in vivo catabolism of low density lipoprotein (LDL) from hypercholesterolemic pigs carrying a mutant apolipoprotein B allele. In the present studies, we examined the in vitro metabolism of mutant LDL in cultur
Autor:
Alan D. Attie, Ronald M. Krauss, W L Fitch, M P Smith, Catharine L. Smith, Jan Rapacz, W J Checovich
Publikováno v:
Biochemistry. 27(6)
Metabolic and chemical properties of low-density lipoproteins (LDLs) were studied in a strain of pigs carrying a specific apo-B allele associated with hypercholesterolemia and premature atherosclerosis. LDL mass was significantly greater in mutant th
Publikováno v:
The Journal of biological chemistry. 263(30)
We previously identified a defect in the in vivo catabolism of low density lipoprotein (LDL) from hypercholesterolemic pigs carrying a mutant apolipoprotein B allele. In the present studies, we examined the in vitro metabolism of mutant LDL in cultur