Zobrazeno 1 - 10
of 45
pro vyhledávání: '"W J, van der Vijgh"'
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(5)
The flavonoid 7-monohydroxyethylrutoside (monoHER) can protect against doxorubicin-induced cardiotoxicity. A drawback of monoHER therapy would be the relatively high dose needed to obtain complete protection (500 mg/kg in mice). Therefore, we synthes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::93d36ba0c4aa1dfb27fc7cb0aca963c5
https://pubmed.ncbi.nlm.nih.gov/11350909
https://pubmed.ncbi.nlm.nih.gov/11350909
Publikováno v:
Anticancer research. 20(6B)
Cardiotoxicity, a side-effect that can occur after treatment with an anticancer drug, has severe clinical implications. Therefore, a model is desired to screen new anticancer drugs or drug combinations for possible cardiotoxic side-effects. In the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5549fcd0f336dba6aba9dd3e17975c9f
https://pubmed.ncbi.nlm.nih.gov/11205292
https://pubmed.ncbi.nlm.nih.gov/11205292
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(4)
Doxorubicin is a very effective antitumor agent, but its clinical use is limited by the occurrence of a cumulative dose-related cardiotoxicity, resulting in congestive heart failure. 7-Monohydroxyethylrutoside (monoHER), a flavonoid belonging to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e6f107e7d6701cec0dff92afcbcf7c5f
https://pubmed.ncbi.nlm.nih.gov/10778960
https://pubmed.ncbi.nlm.nih.gov/10778960
Autor:
C J, van Groeningen, W J, Van der Vijgh, J J, Baars, H, Stieltjes, K, Huibregtse, H M, Pinedo
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(4)
Metabolic conversion of CPT-11 is a major route of elimination of this new topoisomerase 1 inhibitor. Presently, recommendations for dose adjustments of CPT-11 in patients with liver dysfunction are lacking. We describe the case of a patient with met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::089dcfbc87ba626b7b411e06f39ab6e0
https://pubmed.ncbi.nlm.nih.gov/10778961
https://pubmed.ncbi.nlm.nih.gov/10778961
Publikováno v:
Clinical chemistry. 46(2)
Intestinal strontium absorption is becoming accepted as a clinical and diagnostic tool for assessing intestinal calcium absorption in humans. However, little is known about whether intestinal strontium absorption, like that of calcium, is stimulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ceacc26758df6c3ea925e8c3a05f57e
https://pubmed.ncbi.nlm.nih.gov/10657381
https://pubmed.ncbi.nlm.nih.gov/10657381
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(9)
The purpose of this study was to determine the influence of impaired renal and liver function on the pharmacokinetics and pharmacodynamics of lobaplatin in cancer patients. A total of 25 patients with advanced solid tumors not amenable for standard t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a9516e80f6cabbd84a47d833fd61482e
https://pubmed.ncbi.nlm.nih.gov/10499604
https://pubmed.ncbi.nlm.nih.gov/10499604
Publikováno v:
Clinical endocrinology. 50(3)
Impaired intestinal calcium absorption in postmenopausal women is often indirectly linked to decreased serum 1,25(OH)2D or to intestinal resistance to its action rather than directly to low circulating oestrogen levels following the menopause. The pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d16550c829705670ed14bdcd56cbb762
https://pubmed.ncbi.nlm.nih.gov/10435066
https://pubmed.ncbi.nlm.nih.gov/10435066
Autor:
G, Giaccone, S C, Linn, J, Welink, G, Catimel, H, Stieltjes, W J, van der Vijgh, C, Eeltink, J B, Vermorken, H M, Pinedo
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 3(11)
Forty-two patients with advanced solid tumors were entered into a dose-finding study of the combination of doxorubicin with the cyclosporin analogue SDZ PSC 833 (PSC), given by oral route. Patients received PSC at escalating doses, ranging from 2.5 t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf629c4c281edf6d31db2e0b48ecd249
https://pubmed.ncbi.nlm.nih.gov/9815591
https://pubmed.ncbi.nlm.nih.gov/9815591
Autor:
A E, Korst, M L, van der Sterre, H E, Gall, A M, Fichtinger-Schepman, J B, Vermorken, W J, van der Vijgh
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 4(2)
The pharmacokinetics of cisplatin was investigated in 13 patients receiving 18 courses of cisplatin alone or in combination with amifostine to investigate the influence of amifostine (WR 2721; Ethyol) on the pharmacokinetics of cisplatin. Cisplatin w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8ec4ff35fa2ba79ff7e8986fb8960afa
https://pubmed.ncbi.nlm.nih.gov/9516919
https://pubmed.ncbi.nlm.nih.gov/9516919
Autor:
M J, Welters, A M, Fichtinger-Schepman, R A, Baan, M A, Hermsen, W J, van der Vijgh, J, Cloos, B J, Braakhuis
Publikováno v:
International journal of cancer. 71(3)
Patients with head and neck squamous cell carcinoma (HNSCC) treated with cisplatin show a large inter-individual variation in tumor response. Little is known about factors that contribute to this variation. The aim of our study was to correlate the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac0247c85c7d8a78b30fa5d0bffe9e70
https://pubmed.ncbi.nlm.nih.gov/9139877
https://pubmed.ncbi.nlm.nih.gov/9139877