Zobrazeno 1 - 10 of 49 pro vyhledávání: '"W J, Waddell"'
1
The FEMA GRAS assessment of pyrazine derivatives used as flavor ingredients. Flavor and Extract Manufacturers Association
Autor: T B, Adams, J, Doull, V J, Feron, J I, Goodman, L J, Marnett, I C, Munro, P M, Newberne, P S, Portoghese, R L, Smith, W J, Waddell, B M, Wagner
Publikováno v: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 40(4)
This is the fifth in a series of safety evaluations performed by the Expert Panel of the Flavor and Extract Manufacturers Association (FEMA). In 1993, the Panel initiated a comprehensive program to re-evaluate the safety of more than 1700 GRAS flavor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::35f3c579025ba0c7848550df19ce4816
https://pubmed.ncbi.nlm.nih.gov/11893403
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4
Studies on inhibition and induction of metabolism of ethyl carbamate by acetone and related compounds. Evidence for metabolism by cytochromes P-450
Autor: N, Kurata, H E, Hurst, F W, Benz, R A, Kemper, W J, Waddell
Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 19(2)
Ethanol and a variety of other compounds previously have been shown to acutely inhibit the metabolism of ethyl carbamate (EC) when given concurrently in mice. On the other hand, ethanol pretreatment (10% in drinking water for the period 48 to 12 hr p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1c9bd34175ea494dd3a169383dce2768
https://pubmed.ncbi.nlm.nih.gov/1676642
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5
Studies on induction of metabolism of ethyl carbamate in mice by ethanol
Autor: N, Kurata, H E, Hurst, R A, Kemper, W J, Waddell
Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 19(1)
Acute administration of ethanol, acetaldehyde, dimethyl sulfoxide and several other compounds has been reported previously by this laboratory to inhibit the metabolism of ethyl carbamate (E.C.) in mice. Since many enzyme systems that are inhibited by
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3ce81d88a6f0a70ce0fc82afbf34484d
https://pubmed.ncbi.nlm.nih.gov/1673406
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6
Inhibition of the metabolism of ethyl carbamate by acetaldehyde
Autor: N, Kurata, R, Kemper, H E, Hurst, W J, Waddell
Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 18(4)
Ethyl carbamate is an animal carcinogen when administered in large doses; it is naturally present in minute concentrations in fermented foods and beverages. Previous studies from this laboratory have demonstrated that ethanol, in vivo, inhibits the m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7d976f1f08fb9c0ff73d0f64332aaf70
https://pubmed.ncbi.nlm.nih.gov/1976075
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7
Ethyl carbamate metabolism: in vivo inhibitors and in vitro enzymatic systems
Autor: T, Yamamoto, W M, Pierce, H E, Hurst, D, Chen, W J, Waddell
Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 18(3)
The metabolism of ethyl carbamate and the localization of its metabolites have been shown to be almost completely inhibited by ethanol in the mouse [Waddell, Marlowe, Pierce: Food Chem. Toxicol.25, 527 (1987); Yamamoto, Pierce, Hurst, Chen, Waddell:
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::92abf25544871a199835faf71b647edf
https://pubmed.ncbi.nlm.nih.gov/1974186
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8
The distribution of [14C]acrylamide in rainbow trout studied by whole-body autoradiography
Autor: W J, Waddell, J J, Lech, C, Marlowe, K M, Kleinow, M A, Friedman
Publikováno v: Fundamental and applied toxicology : official journal of the Society of Toxicology. 14(1)
The distribution of [2,3-14C]acrylamide was studied in fingerling rainbow trout by whole-body autoradiography. Fish weighing approximately 7 g were injected ip with 3.2 mg/kg [14C]acrylamide (0.1 microCi/g). One group of fish was kept in a fresh flow
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ce150880de1ca9dbc5f17b4ea1c1f97c
https://pubmed.ncbi.nlm.nih.gov/2307324
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