Zobrazeno 1 - 10
of 17
pro vyhledávání: '"W J, Roesler"'
Publikováno v:
Journal of Biological Chemistry. 266:7784-7792
We recently reported the 5'-flanking nucleotide sequence of a putative glutamine synthetase (GS) gene from 3T3-L1 cells (Bhandari, B., Beckwith, K. D. & Miller, R. E. (1988) Proc. Natl. Acad. Sci. U.S.A. 85, 5789-5793). We now find that this gene (GS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20407b70cb9abca0fc27e8c1cf2ed651
https://doi.org/10.1016/s0021-9258(20)89519-2
https://doi.org/10.1016/s0021-9258(20)89519-2
Publikováno v:
Biochemical pharmacology. 62(8)
Phosphoenolpyruvate carboxykinase (PEPCK) is the rate-limiting enzyme of gluconeogenesis. Enhanced expression of the PEPCK gene in liver is present in most models of diabetes, and is thought to contribute to the increased hepatic glucose output seen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::92cea35c07d3477aea6238b443dec4ea
https://pubmed.ncbi.nlm.nih.gov/11597575
https://pubmed.ncbi.nlm.nih.gov/11597575
Autor:
W J, Roesler
Publikováno v:
Molecular and cellular endocrinology. 162(1-2)
Phosphoenolpyruvate carboxykinase (PEPCK) is the rate-limiting enzyme of gluconeogenesis, and most, if not all, of the regulation of its activity is exerted at the level of gene expression, with transcriptional regulation being the most predominant.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ec03574baf1804507d3e2ca270f661f
https://pubmed.ncbi.nlm.nih.gov/10854692
https://pubmed.ncbi.nlm.nih.gov/10854692
Autor:
S M, Crosson, W J, Roesler
Publikováno v:
The Journal of biological chemistry. 275(8)
The CCAAT/enhancer-binding protein alpha (C/EBP) is a transcription factor that trans-activates a number of metabolically important genes. Previous work has demonstrated that C/EBPalpha and C/EBPbeta have the potential to mediate the cAMP responsiven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bbd092b8b5c9a9e3648742e5b07aa693
https://pubmed.ncbi.nlm.nih.gov/10681569
https://pubmed.ncbi.nlm.nih.gov/10681569
Autor:
W J, Roesler, E A, Park
Publikováno v:
Molecular and cellular biochemistry. 178(1-2)
The transcription rate of many genes, and particularly those which code for metabolically important proteins, is regulated by various hormones. Detailed analysis of the promoters of these genes has shown that, while functional 'Hormone response eleme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2a037f1d78c2ef098f884ffaa1509209
https://pubmed.ncbi.nlm.nih.gov/9546576
https://pubmed.ncbi.nlm.nih.gov/9546576
Publikováno v:
The Journal of biological chemistry. 269(19)
The cAMP response unit of the phosphoenolpyruvate carboxykinase (GTP) (EC 4.1.1.32) gene promoter consists of two independently weak components; the typical cAMP response element and a region of the promoter that contains three binding sites for CCAA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::32880abe6d15336d9d86d4b5a21a7b98
https://pubmed.ncbi.nlm.nih.gov/8188712
https://pubmed.ncbi.nlm.nih.gov/8188712
Publikováno v:
The Journal of biological chemistry. 268(5)
A detailed analysis of the promoter sequence requirements for the cAMP induction of transcription of the gene for phosphoenolpyruvate carboxykinase (GTP) (EC 4.1.1.32) was undertaken. It was determined that the cAMP-responsive unit of this promoter c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f5d3a39bc4e50bf576ef91dd41b12d2e
https://pubmed.ncbi.nlm.nih.gov/8381439
https://pubmed.ncbi.nlm.nih.gov/8381439
Publikováno v:
The Journal of biological chemistry. 267(29)
It has been previously demonstrated that the CCAAT/enhancer-binding protein (C/EBP) trans-activates the gene coding for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) (EC 4.1.1.32) (PEPCK) and binds to several sites along the promoter.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::52e0e32647af686934ca4d4c52e46002
https://pubmed.ncbi.nlm.nih.gov/1328227
https://pubmed.ncbi.nlm.nih.gov/1328227
Publikováno v:
The Journal of biological chemistry. 266(28)
The cis elements involved in the cAMP regulation of transcription of the gene for phosphoenolpyruvate carboxykinase (GTP) (EC 4.1.1.32) (PEPCK) were studied by introducing a series of block mutations (10-15 base pairs of random sequence) into eight o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8578b188c51d03e1fd1e4847cf3ddebc
https://pubmed.ncbi.nlm.nih.gov/1655770
https://pubmed.ncbi.nlm.nih.gov/1655770
Publikováno v:
The Journal of biological chemistry. 266(12)
We recently reported the 5'-flanking nucleotide sequence of a putative glutamine synthetase (GS) gene from 3T3-L1 cells (Bhandari, B., Beckwith, K. D.Miller, R. E. (1988) Proc. Natl. Acad. Sci. U.S.A. 85, 5789-5793). We now find that this gene (GSr)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e8f8a7bd7aa718041eed29ac3adfcbd9
https://pubmed.ncbi.nlm.nih.gov/1673462
https://pubmed.ncbi.nlm.nih.gov/1673462