Zobrazeno 1 - 10
of 19
pro vyhledávání: '"W J, Pigram"'
Autor:
W. J. Pigram, S. A. Mason, Watson Fuller, D. Alexeev, V.T. Forsyth, Paul Langan, A. Mahendrasingan, Y. Al-Hayalee
Publikováno v:
Physica B: Condensed Matter. :737-739
The instrument D19 at the Institut Laue-Langevin, Grenoble, has been used to undertake neutron fibre diffraction studies of the location of water around the D form of the DNA double helix. These studies clearly show the distribution of water in the s
Publikováno v:
Basic life sciences. 64
The development of neutron high angle fiber diffraction to investigate the location of water around the deoxyribonucleic acid (DNA) double-helix is described. The power of the technique is illustrated by its application to the D and A conformations o
Autor:
W. J. Pigram, Arumugam Mahendrasingam, Sax A. Mason, V.T. Forsyth, Watson Fuller, Paul Langan
Publikováno v:
Journal of biomolecular structuredynamics. 10(3)
A high angle neutron fibre diffraction study of the distribution of water around the A-form of DNA has been performed using the diffractometer D19 at the Institut Laue-Langevin, Grenoble. These experiments have exploited the ability to replace H2O su
Autor:
R. J. Greenall, W. J. Pigram, Colin Nave, Arumugam Mahendrasingam, Watson Fuller, R. Hussain, V.T. Forsyth
Publikováno v:
Biochemical Society Transactions. 14:553-557
Autor:
Arumugam Mahendrasingam, K. Bellamy, W. J. Pigram, R. J. Greenall, V.T. Forsyth, Watson Fuller, Sax A. Mason
Publikováno v:
International Journal of Biological Macromolecules. 11:236-240
Interactions with water are crucial to the conformation assumed by the DNA double helix. The location of water around the D conformation has been investigated in a neutron fibre diffraction study which shows that water is ordered in the minor groove
Publikováno v:
Journal of Molecular Biology. 168:897-901
Conditions are described for observing by X-ray fibre diffraction the A, B and S conformations of the poly[d(G-C)] . poly[d(G-C)] double-helix and also a new form designated as B". For fibres with an appropriate ionic content, transitions between the
Publikováno v:
Nature. 282:880-882
An intriguing topological problem posed by the double-helical Watson-Crick model of DNA is that of unwinding the intertwined strands during replication. Several workers have recently proposed novel side-by-side (SBS) structures for DNA. In all these
Publikováno v:
Science. 233:195-197
Because of the relation between topology and function, there has been much interest in the structural transitions of the various conformations of DNA polymers. The x-ray fiber diffraction analysis system at the Daresbury Synchrotron Radiation Source
Autor:
J. Brahms, Arumugam Mahendrasingam, N. J. Rhodes, W. J. Pigram, D. C. Goodwin, J. Vergne, Watson Fuller, Colin Nave
Publikováno v:
Nature. 301:535-537
The synthetic polynucleotide poly[d(AT)].poly[d(AT)] is of interest in studies of the relationship between nucleic acid structure and function. In particular, A + T-rich regions in DNA double helices have been invoked as centres for controlling the t
Autor:
Paul Langan, W. J. Pigram, R. J. Greenall, Watson Fuller, K. Bellamy, Arumugam Mahendrasingam, Y. Al-Hayalee, Sax A. Mason, V.T. Forsyth
Publikováno v:
Physica B: Condensed Matter. :468-470
The diffractometer D19 at the ILL has been used to locate water around the DNA double-helix in fibres of the polynucleotide poly[d(A-T)].poly[d(A-T)]. Neutron fibre diffraction data were recorded to a resolution of 3 A first when the DNA was surround