A new phylodynamic model of Mycobacterium bovis transmission in a multi-host system uncovers the role of the unobserved reservoir

Autor: Stanley W. J. McDowell, David Wright, Robin A. Skuce, Hannah Trewby, Anthony O'Hare, Daniel Balaz, Rowland R. Kao, Carl McCormick

Publikováno v: PLoS Computational Biology, Vol 17, Iss 6, p e1009005 (2021)
O'Hare, A, Balaz, D, Wright, D M, McCormick, C, McDowell, S W J, Skuce, R & Kao, R 2021, ' A new phylodynamic model of Mycobacterium bovis transmission in a multi-host system uncovers the role of the unobserved reservoir ', PLoS Computational Biology . https://doi.org/10.1371/journal.pcbi.1009005
PLoS Computational Biology
O’Hare, A, Balaz, D, Wright, D M, McCormick, C, McDowell, S, Trewby, H, Skuce, R A & Kao, R R 2021, ' A new phylodynamic model of Mycobacterium bovis transmission in a multi-host system uncovers the role of the unobserved reservoir ', PLoS Computational Biology, vol. 17, no. 6, e1009005 . https://doi.org/10.1371/journal.pcbi.1009005

Multi-host pathogens are particularly difficult to control, especially when at least one of the hosts acts as a hidden reservoir. Deep sequencing of densely sampled pathogens has the potential to transform this understanding, but requires analytical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62aca055420cb0da1095e3da1ec35a1e
https://doaj.org/article/a390aae8b8f244dc89907493647c060f

Herd-Level Risk Factors for Bovine Tuberculosis: A Literature Review

Autor: Robin A. Skuce, Adrian R. Allen, Stanley W. J. McDowell

Publikováno v: Veterinary Medicine International, Vol 2012 (2012)

Bovine tuberculosis (TB), caused by Mycobacterium bovis, is one of the most challenging endemic diseases currently facing government, the veterinary profession, and the farming industry in the United Kingdom and Ireland and in several other countries

Externí odkaz: https://doaj.org/article/26f08fa93a2e440797b05ddc09182f3c

Bovine tuberculosis visible lesions in cattle culled during herd breakdowns: the effects of individual characteristics, trade movement and co-infection

Autor: Andrew W. Byrne, Maria Guelbenzu-Gonzalo, Adrian R. Allen, J. McNair, Aoibheann Donaghy, Jordon Graham, Robin A. Skuce, Craig M. Brown, Stanley W. J. McDowell

Publikováno v: BMC Veterinary Research, Vol 13, Iss 1, Pp 1-14 (2017)
BMC Veterinary Research

Background Bovine tuberculosis (bTB), caused by Mycobacterium bovis, remains a significant problem for livestock industries in many countries worldwide including Northern Ireland, where a test and slaughter regime has utilised the Single Intradermal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::317b338340a8c9d1e4cb0d13375b0c7c
http://link.springer.com/article/10.1186/s12917-017-1321-z

Seasonal variation of Fasciola hepatica antibodies in dairy herds in Northern Ireland measured by bulk tank milk ELISA

Autor: Maria Guelbenzu-Gonzalo, Andrew W. Byrne, James McConville, R.E.B. Hanna, Georgina Milne, Stanley W. J. McDowell, Jordon Graham

Publikováno v: Parasitology research. 117(9)

Bovine fasciolosis, caused by the infection of the trematode parasite Fasciola hepatica, remains a problem in dairy herds causing significant production losses. In this study, bulk milk tank samples were utilised to generate a comprehensive survey of

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https://pubmed.ncbi.nlm.nih.gov/29948207

Detectability of bovine TB using the tuberculin skin test does not vary significantly according to pathogen genotype within Northern Ireland

Autor: John Woolliams, Stephen Bishop, Robin A. Skuce, Stanley W. J. McDowell, Adrian R. Allen, Mairead L. Bermingham, David Wright, Thomas R. Mallon, Elizabeth Glass

Publikováno v: Infection, Genetics and Evolution
Wright, D M, Allen, A R, Mallon, T R, McDowell, S W J, Bishop, S C, Glass, E J, Bermingham, M L, Woolliams, J A & Skuce, R A 2013, ' Detectability of bovine TB using the tuberculin skin test does not vary significantly according to pathogen genotype within Northern Ireland ', Infection, Genetics and Evolution, vol. 19, pp. 15-22 . https://doi.org/10.1016/j.meegid.2013.05.011

Strains of many infectious diseases differ in parameters that influence epidemic spread, for example virulence, transmissibility, detectability and host specificity. Knowledge of inter-strain variation can be exploited to improve management and decre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d73999d77a54fbd280a9801b0e80c96e