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Akademický článek

ADAR-mediated RNA editing suppresses sleep by acting as a brake on glutamatergic synaptic plasticity

Autor: J. E. Robinson, J. Paluch, D. K. Dickman, W. J. Joiner

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)

Sleep is postulated to offset buildup in net synaptic strength that occurs during waking experience. Here, the authors identify a role for the RNA editing gene Adar in regulating glutamatergic synaptic plasticity and show that disruption in Adarexpre

Externí odkaz: https://doaj.org/article/ce31aae827ab426bb26dbf8945633928

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hSK4/hIK1, a calmodulin-binding KCa channel in human T lymphocytes. Roles in proliferation and volume regulation

Autor: R, Khanna, M C, Chang, W J, Joiner, L K, Kaczmarek, L C, Schlichter

Publikováno v: The Journal of biological chemistry. 274(21)

Human T lymphocytes express a Ca2+-activated K+ current (IK), whose roles and regulation are poorly understood. We amplified hSK4 cDNA from human T lymphoblasts, and we showed that its biophysical and pharmacological properties when stably expressed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2dd9543bf12970ef8bf8ed1f68e0d51c
https://pubmed.ncbi.nlm.nih.gov/10329683

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