Zobrazeno 1 - 10
of 29
pro vyhledávání: '"W I, Wood"'
Autor:
C Wirth, H Asgari, Keelung Hong, Paul Carter, W I Wood, G A Keller, C Kotts, R Shalaby, Lida Guo, John W. Park
Publikováno v:
Proceedings of the National Academy of Sciences. 92:1327-1331
The product of the HER2 protooncogene, p185HER2, represents an attractive target for cancer immunotherapies. We have prepared anti-p185HER2 immunoliposomes in which Fab' fragments of a humanized anti-p185HER2 monoclonal antibody with antiproliferativ
Publikováno v:
The Journal of Immunology. 152:1783-1789
mAbs against human IL-8 receptor A (IL-8R-A) were generated by immunizing mice with either: 1) peptides corresponding to various extracellular domains of IL-8R-A or 2) transfected 293 cells expressing IL-8R-A (293-71 cells). Among the seven peptides
Publikováno v:
The Journal of Immunology. 148:1261-1264
IL-8 is a proinflammatory cytokine that functions as a chemoattractant for neutrophils. Recently, cDNA clones encoding the human neutrophil IL-8R were isolated by an expression cloning strategy. The amino acid sequence of the human IL-8R was sufficie
Autor:
K C, Wollert, T, Taga, M, Saito, M, Narazaki, T, Kishimoto, C C, Glembotski, A B, Vernallis, J K, Heath, D, Pennica, W I, Wood, K R, Chien
Publikováno v:
The Journal of biological chemistry. 271(16)
Cardiotrophin-1 (CT-1) was recently isolated by expression cloning based on its ability to induce an increase in cell size in neonatal rat ventricular cardiomyocytes. Sequence similarity data suggested that CT-1 is a novel member of a family of struc
Publikováno v:
Science (New York, N.Y.). 269(5230)
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 155(4)
In humans and rabbits two similar IL-8R mediate the chemotaxis and activation of neutrophils induced by alpha chemokines. We present data to suggest that there is only one such IL-8R gene in mice. We then use mice with a targeted deletion of this gen
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 152(4)
mAbs against human IL-8 receptor A (IL-8R-A) were generated by immunizing mice with either: 1) peptides corresponding to various extracellular domains of IL-8R-A or 2) transfected 293 cells expressing IL-8R-A (293-71 cells). Among the seven peptides
Publikováno v:
The Journal of biological chemistry. 268(17)
The human growth hormone (GH) receptor contains an extracellular hormone-binding domain of about 246 amino acids, a single transmembrane domain, and a cytoplasmic region of 350 residues. X-ray crystallographic and functional data show that a single G
Publikováno v:
The Journal of biological chemistry. 268(8)
The mechanism of action of two forms of the prolactin (PRL) receptor was studied using analogs of human growth hormone (hGH). At low concentrations (approximately 1 pM), hGH binds and stimulates proliferation of Nb2 cells containing the 391-residue P
Publikováno v:
The Journal of biological chemistry. 267(23)
Interleukin 8 (IL-8) and melanocyte growth-stimulatory activity/gro (MGSA) are structurally related proinflammatory cytokines that are chemoattractants and activators of neutrophils. Recently, cDNA clones encoding a high affinity IL-8 receptor (IL-8R