Zobrazeno 1 - 10
of 765
pro vyhledávání: '"W I, Higuchi"'
Publikováno v:
Pharmaceutical research. 14(4)
In the present study, to develop a drug delivery system with higher bioactivity in hard tissues by using the self-setting bioactive carbonate apatite cement, we have investigated the effects of sodium bicarbonate content on the in vitro drug release
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1296aeb67480d752f9de353d138f5a7b
https://pubmed.ncbi.nlm.nih.gov/9144729
https://pubmed.ncbi.nlm.nih.gov/9144729
Publikováno v:
Pharmaceutical research. 11(12)
This paper describes an experimental and theoretical evaluation of beta-estradiol (E2) transport in post-surgery fresh human skin in vitro. Necessary auxiliary experimental methods were newly developed for these studies. The experimental fluxes of E2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fd53a27e9cdbe7a94788265b91dfa4f8
https://pubmed.ncbi.nlm.nih.gov/7899244
https://pubmed.ncbi.nlm.nih.gov/7899244
Publikováno v:
Pharmaceutical research. 11(9)
The in vitro passive transport of urea, mannitol, sucrose and raffinose across intact and ethanol treated human epidermal membrane was investigated. The intent of this study was to characterize the barrier properties and permeation pathways of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::39da00d5ec3e58b4646e52e363cd326b
https://pubmed.ncbi.nlm.nih.gov/7816761
https://pubmed.ncbi.nlm.nih.gov/7816761
Publikováno v:
Pharmaceutical research. 11(7)
The use of controlled transdermal delivery of acyclovir (ACV) in the treatment of cutaneous herpes simplex virus type 1 infections in hairless mice was investigated. Using an in vivo animal model (A. Gonsho, et al. Int. J. Pharm. 65:183-194 (1990)) m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fb037a5ebb29307a46a0d8fb7050bce4
https://pubmed.ncbi.nlm.nih.gov/7937545
https://pubmed.ncbi.nlm.nih.gov/7937545
Publikováno v:
Pharmaceutical research. 11(5)
The effects of applied voltage and the duration of application upon human epidermal membrane (HEM) alterations and recovery were investigated. All experiments were conducted using a two-chamber diffusion cell with constant DC voltage (250-4000 mV) ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f276dcd978d01430e78335a967fe5119
https://pubmed.ncbi.nlm.nih.gov/8058638
https://pubmed.ncbi.nlm.nih.gov/8058638
Publikováno v:
Pharmaceutical research. 9(11)
Total flux enhancement of ions during iontophoresis is due primarily to the electrochemical potential gradient. However, secondary effects such as convective solvent flow and, in biological membranes, permeability increases as a result of applied fie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::44b22b52d05332c0ea940194b80aa2ca
https://pubmed.ncbi.nlm.nih.gov/1475225
https://pubmed.ncbi.nlm.nih.gov/1475225
Publikováno v:
Pharmaceutical research. 9(8)
This report describes the study of a novel animal model for the topical treatment of cutaneous herpes virus infections, with a focus upon the relationship between the dermal flux of the antiviral agent and the effectiveness of the topical therapy. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2fae8da4d7af711f4a705f8222aaf26a
https://pubmed.ncbi.nlm.nih.gov/1329068
https://pubmed.ncbi.nlm.nih.gov/1329068
Publikováno v:
Seminars in dermatology. 11(2)
An in vitro physical model approach for describing and predicting transport of molecules and ions across skin is examined. The proposed model is represented by two transport-resistant layers in series: the stratum corneum and the epidermis plus dermi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0e3c87b7a3121e07f61761617cb2faba
https://pubmed.ncbi.nlm.nih.gov/1498018
https://pubmed.ncbi.nlm.nih.gov/1498018
Publikováno v:
Pharmaceutical research. 9(6)
Previous in vitro studies have shown that tauroursodeoxycholate (TUDC)-lecithin (L) micellar solutions solubilize cholesterol (Ch) poorly compared to its 7 alpha-epimer, taurochenodeoxycholate (TCDC). However, in clinical studies ursodeoxycholic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::86af524df9a9d0b4b3730bb39966f248
https://pubmed.ncbi.nlm.nih.gov/1409363
https://pubmed.ncbi.nlm.nih.gov/1409363
Publikováno v:
Pharmaceutical research. 8(7)
The influence of low levels of ethanol on the simultaneous diffusion and metabolism of beta-estradiol (E2 beta) in hairless mouse skin was quantitatively evaluated. A wide range of diffusion/metabolism experiments was conducted with full-thickness sk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a706f8f625efc790abe74de9911e8dda
https://pubmed.ncbi.nlm.nih.gov/1924136
https://pubmed.ncbi.nlm.nih.gov/1924136