Zobrazeno 1 - 10
of 1 648
pro vyhledávání: '"W Harper"'
Autor:
Bojana Jovanović, Daniel Temko, Laura E. Stevens, Marco Seehawer, Anne Fassl, Katherine Murphy, Jayati Anand, Kodie Garza, Anushree Gulvady, Xintao Qiu, Nicholas W. Harper, Veerle W. Daniels, Huang Xiao-Yun, Jennifer Y. Ge, Maša Alečković, Jason Pyrdol, Kunihiko Hinohara, Shawn B. Egri, Malvina Papanastasiou, Raga Vadhi, Alba Font-Tello, Robert Witwicki, Guillermo Peluffo, Anne Trinh, Shaokun Shu, Benedetto Diciaccio, Muhammad B. Ekram, Ashim Subedee, Zachary T. Herbert, Kai W. Wucherpfennig, Anthony G. Letai, Jacob D. Jaffe, Piotr Sicinski, Myles Brown, Deborah Dillon, Henry W. Long, Franziska Michor, Kornelia Polyak
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113564- (2023)
Summary: Triple-negative breast cancer (TNBC) is a heterogeneous disease with limited treatment options. To characterize TNBC heterogeneity, we defined transcriptional, epigenetic, and metabolic subtypes and subtype-driving super-enhancers and transc
Externí odkaz:
https://doaj.org/article/5b7a46fb42fa443eac6a172b0b60048f
Autor:
Shan Qiao, Camryn M. Garrett, Prince N. O. Addo, Oluwafemi Adeagbo, Darius M. Moore, Nobutu Muttau, Anjali Sharma, Clementina Lwatula, Levy Ngosa, McLean Kabwe, Albert Manasyan, J. Anitha Menon, Sharon Weissman, Xiaoming Li, Gary W. Harper
Publikováno v:
American Journal of Men's Health, Vol 17 (2023)
Sexual minority men (SMM) face persistent stigma in Zambia. From a holistic perspective, we aim to explore its impacts within and between multiple socioecological levels, demonstrating how their interactions create a vicious cycle of barriers to the
Externí odkaz:
https://doaj.org/article/9170af11bb484cc7bd5420fe661680d9
Autor:
Daniel Delmonaco, Shannon Li, Christian Paneda, Elliot Popoff, Luna Hughson, Laura Jadwin-Cakmak, Jack Alferio, Christian Stephenson, Angelique Henry, Kiandra Powdhar, Isabella Gierlinger, Gary W Harper, Oliver L Haimson
Publikováno v:
JMIR Formative Research, Vol 7, p e41682 (2023)
BackgroundLesbian, gay, bisexual, transgender, queer, and questioning (LGBTQ+) young people (aged 15 to 25 years) face unique health challenges and often lack resources to adequately address their health information needs related to gender and sexual
Externí odkaz:
https://doaj.org/article/c19ec941631742868f96179165255776
Autor:
Maša Alečković, Simona Cristea, Carlos R. Gil Del Alcazar, Pengze Yan, Lina Ding, Ethan D. Krop, Nicholas W. Harper, Ernesto Rojas Jimenez, Donghao Lu, Anushree C. Gulvady, Pierre Foidart, Marco Seehawer, Benedetto Diciaccio, Katherine C. Murphy, Jason Pyrdol, Jayati Anand, Kodie Garza, Kai W. Wucherpfennig, Rulla M. Tamimi, Franziska Michor, Kornelia Polyak
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
TGFβ signalling is reported to regulate hormone-responsive mammary epithelial progenitors that are associated with breast cancer risk. Here, the authors find that short-term TGFBR1 inhibition prevents tumour formation in rat breast cancer models and
Externí odkaz:
https://doaj.org/article/1cad67a83e124a70947f561786bfe0e4
Autor:
Sylvie Naar, M. Isabel Fernandez, Lisa Todd, Sara K. Shaw Green, Henna Budhwani, April Carcone, Karin Coyle, Gregory A. Aarons, Karen MacDonell, Gary W. Harper
Publikováno v:
Implementation Research and Practice, Vol 4 (2023)
Background Understanding the barriers and facilitators of implementation completion is critical to determining why some implementation efforts fail and some succeed. Such studies provide the foundation for developing further strategies to support imp
Externí odkaz:
https://doaj.org/article/f805ba9474084147b505b6715b6525ab
Autor:
Sarah A. Gutin, Gary W. Harper, Neo Moshashane, Kehumile Ramontshonyana, Rob Stephenson, Starley B. Shade, Jane Harries, Okeoma Mmeje, Doreen Ramogola-Masire, Chelsea Morroni
Publikováno v:
BMC Public Health, Vol 21, Iss 1, Pp 1-17 (2021)
Abstract Background A significant proportion (20-59%) of people living with HIV in sub-Saharan Africa desire childbearing, are of reproductive age, and are in sero-different relationships (~50%). Thus it is plausible that some portion of new HIV tran
Externí odkaz:
https://doaj.org/article/b6905780a9e3465a816279a1594065c6
Autor:
L. A. Cagle, A. L. Linderholm, L. M. Franzi, J. A. Last, S. I. Simon, N. J. Kenyon, R. W. Harper
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Introduction:Neutrophil transmigration is multifactorial and primarily driven by selectins and β2-integrins (CD11b/CD18), whose expression are dependent on the underlying stimulus. Ventilator-induced lung injury (VILI) results in a predominantly CD1
Externí odkaz:
https://doaj.org/article/7419572384ca48e08dcb5d9f0f6f0006
Autor:
Gary W. Harper, Katherine A. Lewis, Gabriella A. Norwitz, Elijah Ochieng Odhiambo, Laura Jadwin-Cakmak, Felix Okutah, Kendall Lauber, Teddy Aloo, Ben Collins, Edwin Gumbe, K Rivet Amico, Kennedy Olango, Wilson Odero, Susan M. Graham
Publikováno v:
Adolescents, Vol 1, Iss 3, Pp 267-282 (2021)
Gay and bisexual male youth in Kenya experience human rights violations, including pervasive stigma and discrimination, and these oppressive forces are associated with elevated rates of mental health concerns. Despite these challenges, many gay and b
Externí odkaz:
https://doaj.org/article/66ca4921afff474191d7cce4a3a06b8c
Autor:
Marxavian Jones, Justin C Smith, Shamia Moore, Antonio Newman, Andrés Camacho-González, Gary W Harper, Carlos Del Río, Sophia A Hussen
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0264680 (2022)
BackgroundHIV-focused organizations, care providers and research programs often hire Black gay, bisexual and other men who have sex with men (GBMSM) in their efforts to reach highly affected communities. Due to their unique social position within and
Externí odkaz:
https://doaj.org/article/82a150a397834ecf85a7f298b3a2704a
Autor:
Laura Jadwin-Cakmak, Sari L. Reisner, Jaclyn M. W. Hughto, Liz Salomon, Miguel Martinez, Elliot Popoff, Bré Anne Rivera, Gary W. Harper
Publikováno v:
BMC Public Health, Vol 19, Iss 1, Pp 1-15 (2019)
Abstract Background In the U.S., transgender and gender diverse (TGD) populations face structural, interpersonal, and individual barriers to healthcare. Less is known, however, about the HIV prevention and treatment experiences of TGD youth in the U.
Externí odkaz:
https://doaj.org/article/294a370c1d9c4dba8c1229019648fb73