Zobrazeno 1 - 10
of 166
pro vyhledávání: '"W Halstead"'
Autor:
Robert M. Campbell, Sean G. Buchanan, James R. Henry, David A. Barda, Gregory D. Plowman, Christoph Reinhard, Bharvin K.R. Patel, Xiang S. Ye, Maria Jose Lallena, Emiko L. Kreklau, Shripad V. Bhagwat, Ricardo Martinez, Matthew Z. Dieter, Bartley W. Halstead, Jennie L. Walgren, Jason R. Manro, Phillip W. Iversen, Michele S. Dowless, Louis F. Stancato, Shobha Bhattachar, Shaoyou Chu, Amit Aggarwal, Yue W. Webster, Yuewei Qian, Li-Chun Chio, Mark S. Marshall, Richard P. Beckmann, Jack A. Dempsey, Darlene S. Barnard, Robert D. Van Horn, Gregory P. Donoho, Andrew Capen, Robert T. Foreman, Sarah M. Bogner, Yi Zeng, Yanzhu Yang, Sonya C. Chapman, Yu-Hua Hui, Carmen Baquero, Karsten Boehnke, Carlos Marugán, Huimin Bian, Xueqian Gong, Raquel Torres, Lei Yan, Jian Du
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ab9e588f7270d239b69faebcc24e90
https://doi.org/10.1158/1535-7163.22506969.v1
https://doi.org/10.1158/1535-7163.22506969.v1
Autor:
Robert M. Campbell, Sean G. Buchanan, James R. Henry, David A. Barda, Gregory D. Plowman, Christoph Reinhard, Bharvin K.R. Patel, Xiang S. Ye, Maria Jose Lallena, Emiko L. Kreklau, Shripad V. Bhagwat, Ricardo Martinez, Matthew Z. Dieter, Bartley W. Halstead, Jennie L. Walgren, Jason R. Manro, Phillip W. Iversen, Michele S. Dowless, Louis F. Stancato, Shobha Bhattachar, Shaoyou Chu, Amit Aggarwal, Yue W. Webster, Yuewei Qian, Li-Chun Chio, Mark S. Marshall, Richard P. Beckmann, Jack A. Dempsey, Darlene S. Barnard, Robert D. Van Horn, Gregory P. Donoho, Andrew Capen, Robert T. Foreman, Sarah M. Bogner, Yi Zeng, Yanzhu Yang, Sonya C. Chapman, Yu-Hua Hui, Carmen Baquero, Karsten Boehnke, Carlos Marugán, Huimin Bian, Xueqian Gong, Raquel Torres, Lei Yan, Jian Du
Although Aurora A, B, and C kinases share high sequence similarity, especially within the kinase domain, they function distinctly in cell-cycle progression. Aurora A depletion primarily leads to mitotic spindle formation defects and consequently prom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0aca539a9e32036f4566410352eeff32
https://doi.org/10.1158/1535-7163.c.6538536.v1
https://doi.org/10.1158/1535-7163.c.6538536.v1
Autor:
Robert M. Campbell, Sean G. Buchanan, James R. Henry, David A. Barda, Gregory D. Plowman, Christoph Reinhard, Bharvin K.R. Patel, Xiang S. Ye, Maria Jose Lallena, Emiko L. Kreklau, Shripad V. Bhagwat, Ricardo Martinez, Matthew Z. Dieter, Bartley W. Halstead, Jennie L. Walgren, Jason R. Manro, Phillip W. Iversen, Michele S. Dowless, Louis F. Stancato, Shobha Bhattachar, Shaoyou Chu, Amit Aggarwal, Yue W. Webster, Yuewei Qian, Li-Chun Chio, Mark S. Marshall, Richard P. Beckmann, Jack A. Dempsey, Darlene S. Barnard, Robert D. Van Horn, Gregory P. Donoho, Andrew Capen, Robert T. Foreman, Sarah M. Bogner, Yi Zeng, Yanzhu Yang, Sonya C. Chapman, Yu-Hua Hui, Carmen Baquero, Karsten Boehnke, Carlos Marugán, Huimin Bian, Xueqian Gong, Raquel Torres, Lei Yan, Jian Du
Supplementary Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b687d979fb87e1752e656129b11b4a8
https://doi.org/10.1158/1535-7163.22506966
https://doi.org/10.1158/1535-7163.22506966
Autor:
Jian Du, Alfonso de Dios, Richard B. Gaynor, James J. Starling, Xiang S. Ye, Amit Aggarwal, Song Wu, Shuyu Li, Yuewei Qian, Gregory P. Donoho, Aimee B. Lin, Bart W. Halstead, Sean E. Sissons, Douglas Zeckner, Robert T. Foreman, Timothy I. Meier, Phillip W. Iversen, Damien M. Cronier, Rose T. Ajamie, Graham N. Wishart, Raquel Torrres, Santiago Carballares, Kevin R. Fales, Emiko L. Kreklau, Maria J. Lallena, Tinggui Yin
PDF - 1128K, Figure S1. Knockdown of CDK7 and CDK9 can inhibit RNAP II CTD P-Ser2 and P-Ser5. Figure S2. LY2857785 and flavopiridol inhibit MCL-1, XIAP protein expression and induce CASP-3 and cleaved PARP in AML cell MV-4-11. Table S1. LY2857785 inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb62eb48bfbf19159c380c73cb9da0d
https://doi.org/10.1158/1535-7163.22500105.v1
https://doi.org/10.1158/1535-7163.22500105.v1
Autor:
Jian Du, Alfonso de Dios, Richard B. Gaynor, James J. Starling, Xiang S. Ye, Amit Aggarwal, Song Wu, Shuyu Li, Yuewei Qian, Gregory P. Donoho, Aimee B. Lin, Bart W. Halstead, Sean E. Sissons, Douglas Zeckner, Robert T. Foreman, Timothy I. Meier, Phillip W. Iversen, Damien M. Cronier, Rose T. Ajamie, Graham N. Wishart, Raquel Torrres, Santiago Carballares, Kevin R. Fales, Emiko L. Kreklau, Maria J. Lallena, Tinggui Yin
XLSX - 54K, Table S2. 261 probsets gene signature in sens and res cell lines in Excel format.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d70fa29c964bb208bbfee904a5d0548e
https://doi.org/10.1158/1535-7163.22500102
https://doi.org/10.1158/1535-7163.22500102
Autor:
Jian Du, Alfonso de Dios, Richard B. Gaynor, James J. Starling, Xiang S. Ye, Amit Aggarwal, Song Wu, Shuyu Li, Yuewei Qian, Gregory P. Donoho, Aimee B. Lin, Bart W. Halstead, Sean E. Sissons, Douglas Zeckner, Robert T. Foreman, Timothy I. Meier, Phillip W. Iversen, Damien M. Cronier, Rose T. Ajamie, Graham N. Wishart, Raquel Torrres, Santiago Carballares, Kevin R. Fales, Emiko L. Kreklau, Maria J. Lallena, Tinggui Yin
DNA-dependent RNA polymerase II (RNAP II) largest subunit RPB1 C-terminal domain (CTD) kinases, including CDK9, are serine/threonine kinases known to regulate transcriptional initiation and elongation by phosphorylating Ser 2, 5, and 7 residues on CT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b805b19504f4ca7d3dd3ca23723e6c77
https://doi.org/10.1158/1535-7163.c.6536355
https://doi.org/10.1158/1535-7163.c.6536355
Autor:
Robert M. Campbell, Sean G. Buchanan, James R. Henry, David A. Barda, Gregory D. Plowman, Christoph Reinhard, Bharvin K.R. Patel, Xiang S. Ye, Maria Jose Lallena, Emiko L. Kreklau, Shripad V. Bhagwat, Ricardo Martinez, Matthew Z. Dieter, Bartley W. Halstead, Jennie L. Walgren, Jason R. Manro, Phillip W. Iversen, Michele S. Dowless, Louis F. Stancato, Shobha Bhattachar, Shaoyou Chu, Amit Aggarwal, Yue W. Webster, Yuewei Qian, Li-Chun Chio, Mark S. Marshall, Richard P. Beckmann, Jack A. Dempsey, Darlene S. Barnard, Robert D. Van Horn, Gregory P. Donoho, Andrew Capen, Robert T. Foreman, Sarah M. Bogner, Yi Zeng, Yanzhu Yang, Sonya C. Chapman, Yu-Hua Hui, Carmen Baquero, Karsten Boehnke, Carlos Marugán, Huimin Bian, Xueqian Gong, Raquel Torres, Lei Yan, Jian Du
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9753ae2ef1911fad6be7d03eb93839c9
https://doi.org/10.1158/1535-7163.22506972.v1
https://doi.org/10.1158/1535-7163.22506972.v1
Autor:
Xueqian Gong, Karsten Boehnke, Carmen Baquero, Yue-Wei Qian, Gregory P. Donoho, Jason Manro, Robert T. Foreman, Carlos Marugán, Sonya C. Chapman, Yi Zeng, Phillip W Iversen, Jack A. Dempsey, Matthew Z. Dieter, David Anthony Barda, Henry James Robert, Michele Dowless, Shripad V. Bhagwat, Robert M. Campbell, Andrew Capen, Robert D. Van Horn, Amit Aggarwal, Mark S. Marshall, Darlene S. Barnard, Bharvin K. R. Patel, Louis Stancato, Huimin Bian, Li-Chun Chio, Sean Buchanan, Jian Du, Richard P. Beckmann, Christoph Reinhard, Ricardo Martinez, Gregory D. Plowman, Lei Yan, Shobha N. Bhattachar, Sarah M. Bogner, Maria Jose Lallena, Xiang S. Ye, Jennie L. Walgren, Yu-Hua Hui, Yue Webster, Emiko L. Kreklau, Raquel Torres, Yanzhu Yang, Bartley W. Halstead, Shaoyou Chu
Publikováno v:
Molecular Cancer Therapeutics. 18:2207-2219
Although Aurora A, B, and C kinases share high sequence similarity, especially within the kinase domain, they function distinctly in cell-cycle progression. Aurora A depletion primarily leads to mitotic spindle formation defects and consequently prom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ea271aab24607f19770d2cdca75d5d3
https://doi.org/10.1158/1535-7163.mct-18-0529
https://doi.org/10.1158/1535-7163.mct-18-0529
Autor:
Minh Duc Bui, Jeff S. Piotrowski, Enhai Xie, Yury V. Bukhman, Trey K. Sato, Nathan W. DiPiazza, Adam G. W. Halstead, Jason Shao
Publikováno v:
BioEnergy Research. 8:1022-1030
In this work, we introduce the Growth Curve Analysis Tool (GCAT). GCAT is designed to enable efficient analysis of high-throughput microbial growth curve data collected from cultures grown in microtiter plates. GCAT is accessible through a web browse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0db550e2517ac38db06930012280499
https://doi.org/10.1007/s12155-015-9584-3
https://doi.org/10.1007/s12155-015-9584-3
Autor:
Jeffrey A. Willy, Thomas K. Baker, George H. Searfoss, Brianna M Paisley, Bartley W. Halstead, Steven K. Engle
Publikováno v:
Translating Molecules into Medicines ISBN: 9783319500409
Early safety assessment efforts from target identification to lead development have undergone rapid growth and evolution over the last 10 years. In this chapter, we will discuss the current development trends driving the need for early safety assessm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db81cb399fbb81e8cb881fc9cd8859e6
https://doi.org/10.1007/978-3-319-50042-3_5
https://doi.org/10.1007/978-3-319-50042-3_5