Zobrazeno 1 - 10
of 45
pro vyhledávání: '"W H Simmons"'
Autor:
H. A. Appleton, W. H. Simmons
In the general advance of technical knowledge and research during the last decade, the Soap Industry has not remained stationary. While there has not perhaps been anything of a very revolutionary character, steady progress has still been made in prac
Autor:
Anne-Marie Irani, Timothy R. Bradford, T Huff, H Miller, Shirley S. Craig, Lawrence B. Schwartz, Z Chen, G Newlands, W H Simmons
Publikováno v:
Journal of Histochemistry & Cytochemistry. 41:961-969
We examined the cellular distribution of rat tryptase in rat skin, lung, small intestine, and peritoneal lavage cells by immunohistochemical techniques. Tryptase purified to apparent homogeneity from rat skin was used to generate a goat polyclonal an
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 292(1)
Bradykinin is a nonapeptide that contributes to the cardioprotective effects of angiotensin-converting enzyme (ACE) inhibitors. During ACE inhibition, an increased proportion of bradykinin is degraded through non-ACE pathways. Studies in animals sugg
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 354
Injection of substance P (SP) in a rat hindpaw induced extravasation of 125I-labelled albumin in both hindpaws and salivation. Intravenous injection of SP dose-dependently increased vascular permeability. This latter effect was increased in rat paws
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 354(5)
The influence of some peptidase inhibitors on oedema and plasma extravasation induced by bradykinin and carrageenan in rat paw was evaluate. Bradykinin-induced oedema in normal rats was increased by o-phenanthroline (3.10(-2) M), by captopril (10(-6)
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 275(3)
Bradykinin (Bk), a potent vasoactive and cardioprotective peptide hormone, is almost completely inactivated during a single circulation through the rat lung. It has been hypothesized that membrane-bound aminopeptidase P, which can hydrolyze the Arg1-
Publikováno v:
British journal of pharmacology. 114(1)
We examined whether a specific aminopeptidase P (APP) inhibitor, apstatin, increases vasodepressor responses to bradykinin in anaesthetized rats, and whether it would augment blood pressure responses further after treatment with the angiotensin-conve
Autor:
W H, Simmons, A T, Orawski
Publikováno v:
The Journal of biological chemistry. 267(7)
The membrane-bound form of aminopeptidase P (aminoacylprolyl-peptide hydrolase) (EC 3.4.11.9) was purified to apparent homogeneity from bovine lung microsomes. The enzyme was solubilized using phosphatidylinositol-specific phospholipase C (Bacillus t
Autor:
A T, Orawski, W H, Simmons
Publikováno v:
Agents and actions. Supplements. 38
Aminopeptidase P that hydrolyzes the Arg1-Pro2-bond of bradykinin was solubilized from rat lung microsomes using phosphatidylinositol-specific phospholipase C. The enzyme was purified 420-fold by chromatography on decylagarose (two steps), omega-amin
Autor:
W. H. Simmons
Publikováno v:
The Police Journal: Theory, Practice and Principles. 22:117-121