Zobrazeno 1 - 9
of 9
pro vyhledávání: '"W H Haile"'
Publikováno v:
Oncology research. 7(10-11)
A clinically relevant mechanism of acquired methotrexate (MTX) resistance is decreased MTX polyglutamate (MTXGn) synthesis (McCloskey et al. J. Biol. Chem. 266:6181, 1991) secondary to deficient folylpolyglutamate synthetase (FPGS) activity. Earlier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::832f90a52b8fc7a88995981ac40e4cf2
https://pubmed.ncbi.nlm.nih.gov/8866666
https://pubmed.ncbi.nlm.nih.gov/8866666
Autor:
J J, McGuire, V V, Bergoltz, K J, Heitzman, W H, Haile, C A, Russell, W E, Bolanowska, Y, Kotake, T, Haneda, H, Nomura
Publikováno v:
Cancer research. 54(10)
Six novel antifolates with 2,4-diaminopyrimidine-fused five-membered rings containing either pyrrole or cyclopentene rings were characterized at the cellular and biochemical level. Five of these antifolates were more growth inhibitory to the CCRF-CEM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4b8e9c0bd817c13ee0dd8b1de8393585
https://pubmed.ncbi.nlm.nih.gov/8168096
https://pubmed.ncbi.nlm.nih.gov/8168096
Publikováno v:
Leukemia. 7(12)
CCRF-CEM human leukemia sublines resistant to short-term methotrexate (MTX) exposure as a result of decreased folylpolyglutamate synthetase (FPGS) activity were examined for their response to other cytotoxic agents. The R3/7 and R30dm sublines displa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::beddb6c2687484e6d521e85a1763d0ad
https://pubmed.ncbi.nlm.nih.gov/8255099
https://pubmed.ncbi.nlm.nih.gov/8255099
Publikováno v:
Advances in experimental medicine and biology. 338
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3e8dd29734a2e4a302e0c2e6ff870930
https://pubmed.ncbi.nlm.nih.gov/8304203
https://pubmed.ncbi.nlm.nih.gov/8304203
Publikováno v:
The Journal of biological chemistry. 265(24)
The effect of 3,3-difluoroglutamate (F2Glu) on the reaction catalyzed by rat liver folypolyglutamate synthetase was investigated. F2Glu was a potent, concentration-dependent inhibitor of poly(gamma-glutamylation) using [3H]Glu and either methotrexate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::82447dc8a8c3f5e9cc2308da6aa7f262
https://pubmed.ncbi.nlm.nih.gov/1974895
https://pubmed.ncbi.nlm.nih.gov/1974895
Autor:
W M Griffith, W H Haile, J A Saner, A Sykes, R G Clark, E J Silcock, B Howorth, E C Hillman, O Borer, W J E Binnie, G J Griffiths, C D C Braine, D G Hill
Publikováno v:
Journal of the Institution of Civil Engineers. 2:412-440
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cb28c7bf04fbbb11b093cee78ea603a
https://doi.org/10.1680/ijoti.1936.14840
https://doi.org/10.1680/ijoti.1936.14840
Autor:
W H HAILE, H CHEETHAM, J T THIJSSE, W E DORAN, H C BOWEN, W P THOMPSON, G W ROOKE, H D MORGAN, P FRANK, C CLAY, I P HAIGH, J H JELLETT, T P O SULLIVAN, B STANDING, C INGLIS
Publikováno v:
Journal of the Institution of Civil Engineers. 35:153-169
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dccdb3cf518f751a78d806f93f3ba49b
https://doi.org/10.1680/ijoti.1951.12767
https://doi.org/10.1680/ijoti.1951.12767
Autor:
R C Parsons, Cc James, L F Mountfort, B Meek, D C Leitch, G W Humphreys, W H Haile, K Allen, A Hazen, G B Kershaw, H A Roechling, E J Silcock
Publikováno v:
Minutes of the Proceedings of the Institution of Civil Engineers. 204:81-106
n/a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37bfb0f4c5e2dc8e98fcfc0c1c447891
https://doi.org/10.1680/imotp.1917.15749
https://doi.org/10.1680/imotp.1917.15749
Publikováno v:
Journal of the Institution of Civil Engineers. 36:20-21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b82859fd3eac181dbc28c139b0a5b9bc
https://doi.org/10.1680/ijoti.1951.12704
https://doi.org/10.1680/ijoti.1951.12704