Výsledky vyhledávání - "W H, Ouwehand"

Immunologic and structural analysis of eight novel domain-deletion β3integrin peptides designed for detection of HPA-1 antibodies

Autor: P, Stafford, C, Ghevaert, K, Campbell, C, Proulx, G, Smith, L M, Williamson, E, Ranasinghe, N A, Watkins, J A, Huntington, W H, Ouwehand

Publikováno v: Journal of Thrombosis and Haemostasis. 6:366-375

The single-nucleotide polymorphism (SNP) rs5918 in the ITGB3 gene defines the human platelet antigen-1 (HPA-1) system encoding a Leu (HPA-1a) or Pro (HPA-1b) at position 33. HPA-1 antibodies are clinically the most relevant in the Caucasoid populatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da16776491cac89540587111392d6cc0
https://doi.org/10.1111/j.1538-7836.2007.02858.x

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Localization of the platelet-specific HPA-2 (Ko) alloantigens on the N- terminal globular fragment of platelet glycoprotein Ib alpha

Autor: P. M. M. Bleeker, R. W. A. M. Kuijpers, A. E. G. K. Von Dem Borne, W. H. Ouwehand, D. Christie

Publikováno v: Blood. 79:283-288

The human platelet-specific alloantigens HPA-2a and HPA-2b (= Kob and Koa) together constitute a biallelic antigen system. The HPA-2 antigens have not, to date, been located on a particular platelet membrane molecule. Here, we describe the localizati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::91d9091316b03d408a7695dc41e9efdb
https://doi.org/10.1182/blood.v79.1.283.283

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Quantification of platelet-bound immunoglobulins of different class and subclass using radiolabeled monoclonal antibodies: assay conditions and clinical application

Autor: A. E. G. Kr. von dem Borne, R. J. L. Klaassen, W. H. Ouwehand, P. W. Modderman, G. J. Tijhuis

Publikováno v: British Journal of Haematology. 77:93-101

Summary. Quantification of platelet-bound immunoglobulins (PBIg) with radiolabelled murine monoclonal antibodies (mAbs) has been described only for IgG so far. Here we describe some modifications of this mAb radioimmunoassay (MARIA) and show that by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04666bb58710190950bcaae4a6e6ad03
https://doi.org/10.1111/j.1365-2141.1991.tb07954.x

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The importance of using multiple techniques for detection of platelet antibodies

Autor: G A, Smith, E, Ranasinghe, W H, Ouwehand

Publikováno v: Vox sanguinis. 93(4)

In red cell immunology, it has long been known that no one technique will detect all clinically significant antibodies. The same appears to be true for platelet immunology, and we highlight this fact by showing four examples of anti-human platelet an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2c9e22efe7df44e0356845032999a9ce
https://pubmed.ncbi.nlm.nih.gov/18070274

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Interlaboratory variation in the detection of HPA-specific alloantibodies and in molecular HPA typing

Autor: D, Allen, W H, Ouwehand, M, de Haas, R, Kekomaki, C, Kaplan, P, Metcalfe

Publikováno v: Vox sanguinis. 93(4)

Platelet immunology quality assurance exercises have been organized by National Institute for Biological Standards and Control since 1991 and, as of 2006, 35 laboratories participate in the serology section. Molecular human platelet antigen (HPA) typ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ff17529289e5137a6f6097e1e75c925a
https://pubmed.ncbi.nlm.nih.gov/18070276

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Report on the 13th International Society of Blood Transfusion Platelet Immunology Workshop

Autor: Z, Foxcroft, K, Campbell, Y, Merieux, S, Urbaniak, M, Brierley, D, Rigal, W H, Ouwehand, P, Metcalfe

Publikováno v: Vox sanguinis. 93(4)

The aim of the 13th International Society of Blood Transfusion Platelet Immunology Workshop was to compare the sensitivity and specificity of the in-house method for the detection of human platelet antigen (HPA) antibodies currently used in participa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3077cd06f754221eb27ca9aa5ed38027
https://pubmed.ncbi.nlm.nih.gov/18070273

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Severe fetomaternal alloimmune thrombocytopenia due to anti-human platelet antigen (HPA)-1a in a mother with a rare and silenced ITGB3*0101 (GPIIIa) allele

Autor: G A, Smith, A, Rankin, C, Riddle, C, Cheetham-Wilkinson, E, Ranasinghe, W H, Ouwehand, N A, Watkins

Publikováno v: Vox sanguinis. 93(4)

Fetomaternal alloimmune thrombocytopenia (FMAIT) is caused by maternal antibodies against a human platelet antigen (HPA) present on fetal, but absent from maternal platelets. We identified and characterized a case of FMAIT due to anti-HPA-1a in a mot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0e12479c131af389cd8fd9688d8c5a04
https://pubmed.ncbi.nlm.nih.gov/18070277

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Genotyping for platelet-specific antigens: techniques for the detection of single nucleotide polymorphisms

Autor: C M, Hurd, G, Cavanagh, A, Schuh, W H, Ouwehand, P, Metcalfe

Publikováno v: Vox sanguinis. 83(1)

Accurate typing of patients for platelet-specific (human platelet) antigens (HPA) is required in several different clinical situations, and blood services need to maintain panels of HPA-typed apheresis platelet donors and whole-blood donors to suppor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4dfbe2e2717e23ab03fd5ff9b32e228a
https://pubmed.ncbi.nlm.nih.gov/12100382

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Provision of platelet support for fetuses and neonates affected by severe fetomaternal alloimmune thrombocytopenia

Autor: E, Ranasinghe, J D, Walton, C M, Hurd, L, Saul, G, Smith, K, Campbell, W H, Ouwehand

Publikováno v: British journal of haematology. 113(1)

Severe fetomaternal alloimmune thrombocytopenia requires urgent treatment with compatible platelet concentrates. As prompt treatment is sometimes delayed owing to the unavailability of compatible platelets, we established an accredited platelet donor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f86621693f9dcc94ddf06020bef7ecc9
https://pubmed.ncbi.nlm.nih.gov/11972538

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