Zobrazeno 1 - 7
of 7
pro vyhledávání: '"W H, Isacoff"'
Publikováno v:
The American surgeon. 66(9)
The accuracy of endoscopic ultrasound (EUS) for initial staging of esophageal cancer is widely accepted. There is, however, considerable variability in the reported accuracy of EUS for restaging of esophageal neoplasms after neoadjuvant therapy. From
Publikováno v:
Journal of Clinical Oncology. 24:14023-14023
14023 Background: Our laboratory studies suggest additive to synergistic cytotoxicity when neuroendocrine (NET) cells were given continuous exposure to 5 fluorouracil (5-FU) which preceded exposure to temozolomide (T). Based on this in vitro efficacy
Publikováno v:
Medical Informatics. 2:163-172
Computer tools for data analysis such as CLINFO can be combined with modern laboratory measurement techniques to provide quantitative practical rules for therapeutic decision-making in cancer chemotherapy. The analysis of extensive data on the cleara
Autor:
W H, Isacoff, F, Eilber, H, Tabbarah, P, Klein, M, Dollinger, S, Lemkin, P, Sheehy, L, Cone, B, Rosenbloom, L, Sieger, J B, Block
Publikováno v:
Cancer treatment reports. 62(9)
One hundred and thirty-four patients with advanced malignant disease were treated with 496 infusions of high-dose methotrexate (HD-MTX) followed by citrovorum factor rescue. Most patients had failed to respond to previous combination chemotherapy. Th
Publikováno v:
Cancer treatment reports. 68(4)
The deoxyuridine (dU) suppression test, which estimates the activity of the de novo pathway to DNA synthesis from dU, was evaluated as a predictor of antimetabolite growth inhibition. Observations of growth inhibition were made using flask cell cultu
Autor:
J B, Block, W H, Isacoff
Publikováno v:
Seminars in oncology. 4(1)
Publikováno v:
Cancer treatment reports. 61(9)
The methotrexate (MTX)-plasma concentrations of 172 high-dose infusions over the range of 50-200 mg/kg were measured over the 72-hour period following the beginning of infusion. Pharmacokinetic analysis shows that a biexponential function adequately