Zobrazeno 1 - 10 of 13 pro vyhledávání: '"W H, Dokter"'
1
IL-7 enhances the expression of IL-3 and granulocyte-macrophage-CSF mRNA in activated human T cells by post-transcriptional mechanisms
Autor: W H Dokter, S J Sierdsema, M T Esselink, M R Halie, E Vellenga
Publikováno v: The Journal of Immunology. 150:2584-2590
The stromal derived growth factor IL-7 was studied for its ability to modulate cytokine expression in human T cells. IL-7 alone did not induce IL-3 or granulocyte-macrophage-CSF (GM-CSF) mRNA. However, IL-7 enhanced the Con A-induced IL-3 and GM-CSF
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8fc25452c96723b81882206317ff0852
https://doi.org/10.4049/jimmunol.150.7.2584
Zobrazit plný text záznamu
2
The epithelial glycoprotein 2 (EGP-2) promoter-driven epithelial-specific expression of EGP-2 in transgenic mice: a new model to study carcinoma-directed immunotherapy
Autor: P M, McLaughlin, M C, Harmsen, W H, Dokter, B J, Kroesen, H, van der Molen, M G, Brinker, H, Hollema, M H, Ruiters, C H, Buys, L F, de Leij
Publikováno v: Cancer research. 61(10)
The human pancarcinoma-associated epithelial glycoprotein-2 (EGP-2), a M(r) 38,000 transmembrane antigen also known as 17-1A or Ep-CAM, is commonly used for targeted immunotherapy of carcinomas because it is strongly expressed by most carcinomas. EGP
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fc47d7c873ea72167757f5e5573f1636
https://pubmed.ncbi.nlm.nih.gov/11358833
Zobrazit plný text záznamu
3
Interleukin-6-induced STAT3 transactivation and Ser727 phosphorylation involves Vav, Rac-1 and the kinase SEK-1/MKK-4 as signal transduction components
Autor: J J, Schuringa, L J, Jonk, W H, Dokter, E, Vellenga, W, Kruijer
Publikováno v: The Biochemical journal.
In the present study, signal transducer and activator of transcription 3 (STAT3) Ser(727) phosphorylation and transactivation was investigated in relation to activation of mitogen-activated protein (MAP) kinase family members including extracellular-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e149718404116cbb2e45ab2e539d4d5d
https://pubmed.ncbi.nlm.nih.gov/10727406
Zobrazit plný text záznamu
4
Extracellular-regulated kinase 1/2, Jun N-terminal kinase, and c-Jun are involved in NF-kappa B-dependent IL-6 expression in human monocytes
Autor: L M, Tuyt, W H, Dokter, K, Birkenkamp, S B, Koopmans, C, Lummen, W, Kruijer, E, Vellenga
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 162(8)
In the present study we investigated the possible involvement of the mitogen-activated protein kinase family members extracellular-regulated kinase 1/2 (ERK1/2) and c-Jun N-terminal kinase (JNK) in mediating IL-6 gene expression in human monocytes, i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::891affdc030966bce08bd6d82f136131
https://pubmed.ncbi.nlm.nih.gov/10202034
Zobrazit plný text záznamu
5
Effects of IL-10 and IL-4 on LPS-induced transcription factors (AP-1, NF-IL6 and NF-kappa B) which are involved in IL-6 regulation
Autor: W H, Dokter, S B, Koopmans, E, Vellenga
Publikováno v: Leukemia. 10(8)
Interleukin-10 (IL-10), like IL-4, is known to inhibit cytokine expression in activated human monocytes. We showed that both IL-10 and IL-4 inhibit LPS-induced IL-6 mRNA and protein expression by inhibiting the transcription rate of the IL-6 gene. Th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::20d863bba6c32d43a19f83e7a4d0f877
https://pubmed.ncbi.nlm.nih.gov/8709636
Zobrazit plný text záznamu
6
Divergent effects of IL-10 and IL-4 on the proliferation and growth factor secretion by acute myeloblastic leukemic cells
Autor: L M, Tuyt, W H, Dokter, M T, Esselink, E, Vellenga
Publikováno v: European cytokine network. 6(4)
The effects of interleukin-10 (IL-10) and IL-4 were studied on the spontaneous and IL-1, IL-3, and Granulocyte-Colony Stimulating Factor (G-CSF) supported proliferation of acute myeloid leukemic cells. IL-10 inhibited the spontaneous proliferation in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d317517afc45ad29e6607c7a2dffd261
https://pubmed.ncbi.nlm.nih.gov/8789288
Zobrazit plný text záznamu
7
The spontaneous expression of interleukin-1 beta and interleukin-6 is associated with spontaneous expression of AP-1 and NF-kappa B transcription factor in acute myeloblastic leukemia cells
Autor: W H, Dokter, L, Tuyt, S J, Sierdsema, M T, Esselink, E, Vellenga
Publikováno v: Leukemia. 9(3)
The nature of the spontaneous expression of cytokines that is observed in blasts of some AML patients is unclear. We studied whether or not the spontaneous expression of IL-1 beta and IL-6 is due to an increased transcription rate of the cytokine gen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f82f6763a1fa050c258c6d2243053895
https://pubmed.ncbi.nlm.nih.gov/7885041
Zobrazit plný text záznamu
8
G(Anh)MTetra, a natural bacterial cell wall breakdown product, induces interleukin-1 beta and interleukin-6 expression in human monocytes. A study of the molecular mechanisms involved in inflammatory cytokine expression
Autor: W H, Dokter, A J, Dijkstra, S B, Koopmans, B K, Stulp, W, Keck, M R, Halie, E, Vellenga
Publikováno v: The Journal of biological chemistry. 269(6)
It is believed that induction of cytokine expression by bacterial cell wall components plays a role in the development and course of sepsis. However, most attention has been focused on lipopolysaccharide (LPS). We studied the ability of N-acetylgluco
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8bb319b9f365d4f53d058b800fc195c7
https://pubmed.ncbi.nlm.nih.gov/8307982
Zobrazit plný text záznamu
9
Interleukin-4 mRNA and protein in activated human T cells are enhanced by interleukin-7
Autor: W H, Dokter, S J, Sierdsema, M T, Esselink, M R, Halie, E, Vellenga
Publikováno v: Experimental hematology. 22(1)
We studied the effect of the stroma-derived cytokine interleukin-7 (IL-7) on the expression of IL-4 in human T cells at mRNA and protein level. The results demonstrate that IL-7 did not induce IL-4 mRNA in resting T cells. However, concanavalin A (co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::180e6a67e875db49d65291e49d187573
https://pubmed.ncbi.nlm.nih.gov/8282063
Zobrazit plný text záznamu
10
Interferon-gamma enhances the LPS-induced G-CSF gene expression in human adherent monocytes, which is regulated at transcriptional and posttranscriptional levels
Autor: H, de Wit, W H, Dokter, M T, Esselink, M R, Halie, E, Vellenga
Publikováno v: Experimental hematology. 21(6)
Human adherent monocytes were studied with regard to the expression of granulocyte colony-stimulating factor (G-CSF) at mRNA and protein levels in response to lipopolysaccharide (LPS) and gamma-interferon (IFN-gamma) stimulation. Monocytes did not ex
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::19205cb4565f6694b2764132fd6a2efd
https://pubmed.ncbi.nlm.nih.gov/7684703
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje