Zobrazeno 1 - 10
of 135
pro vyhledávání: '"W Gurd"'
Autor:
Jeanne Zhen Huo, M. Christopher Wallace, Crystal Dykstra, Lucy Teves, James W. Gurd, Salma Rawof, John A.P. Rostas, N. Bissoon
Publikováno v:
Brain Research. 1218:158-165
Ca2+-stimulated protein kinase II (CaMKII) is critically involved in the regulation of synaptic function and is implicated in the neuropathology associated with ischemia and status epilepticus (SE). The activity and localization of CaMKII is regulate
Autor:
Benjamin Jung, Warren Ho, James W. Gurd, M. Christopher Wallace, Denis G.M. Jugloff, James H. Eubanks, Guangming Zhang, Herman H. Cheung
Publikováno v:
Journal of Neurochemistry. 101:263-273
Using mRNA differential display to identify cerebral ischemia-responsive mRNAs, we isolated and cloned a cDNA derived from a novel gene, that has been designated LCHN. Antisense mRNA in situ hybridization and immunoblotting confirmed LCHN expression
Publikováno v:
Neuroscience Letters. 401:266-270
The administration of lithium followed by pilocarpine induces status epilepticus (SE) that produces neurodegeneration and the subsequent development of spontaneous recurrent seizures. We have reported that tyrosine phosphorylation of the NMDA recepto
Publikováno v:
Journal of Neuroscience Research. 81:522-529
Lipid rafts are specialized plasma membrane microdomains enriched in cholesterol and sphingolipids that serve as major assembly and sorting platforms for signal transduction complexes. Constitutively expressed heat shock proteins Hsp90, Hsc70, Hsp60,
Changes in phosphorylation of the NMDA receptor in the rat hippocampus induced by status epilepticus
Autor:
M. Niimura, Norton W. Milgram, N. Bissoon, Candace J. Ikeda-Douglas, James W. Gurd, R. Moussa
Publikováno v:
Journal of Neurochemistry. 92:1377-1385
Systemic administration of pilocarpine preceded by lithium induces status epilepticus (SE) that results in neurodegeneration and may lead to the development of spontaneous recurrent seizures. We investigated the effect of Li/pilocarpine-induced SE on
Publikováno v:
Developmental Neuroscience. 27:211-219
The effects of transient cerebral hypoxia-ischemia (HI) on phosphorylation of the NR1 subunit of the N-methyl-D-aspartate (NMDA) receptor were investigated in 7 (P7)- and 21 (P21)-day-old rats. Unilateral HI was induced by ligation of the right commo
Autor:
Jennifer A. Palarca, B. Glenn Stanley, Derek S. Welsbie, Arshad M. Khan, James W. Gurd, Elizabeth R. Gillard, Herman H. Cheung
Publikováno v:
The Journal of Neuroscience. 24:10603-10615
In rats, feeding can be triggered experimentally using many approaches. Included among these are (1) food deprivation and (2) acute microinjection of the neurotransmitterl-glutamate (Glu) or its receptor agonist NMDA into the lateral hypothalamic are
Publikováno v:
Journal of Neurochemistry. 86:1441-1449
The role of protein kinase C (PKC) in tyrosine phosphorylation of the N-methyl-d-aspartate receptor (NMDAR) following transient cerebral ischemia was investigated. Transient (15 min) cerebral ischemia was produced in adult rats by four-vessel occlusi
Publikováno v:
Journal of Neurochemistry. 69:1060-1065
Activation of the N-methyl-D-aspartate (NMDA) receptor has been implicated in the events leading to ischemia-induced neuronal cell death. Recent studies have indicated that the properties of the NMDA receptor channel may be regulated by tyrosine phos
Autor:
Tadashi Yamamoto, Takanobu Nakazawa, James W. Gurd, Philip W. Beesley, N. Bissoon, Susan J. Vannucci
Publikováno v:
Journal of Neurochemistry. 82:848-856
The effect of cerebral hypoxia-ischemia (HI) on levels and tyrosine phosphorylation of the NMDA receptor was examined in 7- (P7) and 21 (P21)-day-old rats. Unilateral HI was administered by ligation of the right common carotid artery and exposure to