Zobrazeno 1 - 10
of 2 654
pro vyhledávání: '"W Greiner"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
The transcription factor NF-κB is commonly known to drive inflammation and cancer progression, but is also a crucial regulator of a broad range of cellular processes within the mammalian nervous system. In the present review, we provide an overview
Externí odkaz:
https://doaj.org/article/f66cdb252ca043509c41eab34af0268d
Autor:
K. F. Trefz, A. C. Muntau, K. M. Kohlscheen, J. Altevers, C. Jacob, S. Braun, W. Greiner, A. Jha, M. Jain, I. Alvarez, P. Lane, C. Schröder, F. Rutsch
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 14, Iss 1, Pp 1-16 (2019)
Abstract Background Phenylketonuria (PKU) is an inherited deficiency in the enzyme phenylalanine hydroxylase (PAH), which, when poorly-managed, is associated with clinical features including deficient growth, microcephaly, seizures, and intellectual
Externí odkaz:
https://doaj.org/article/cbd15222dad94166bd2243c9c4f981ec
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-11 (2019)
Abstract Background While significant strides in the treatment of metastatic bladder cancer have been made with immune checkpoint inhibitors, the treatment of carcinoma in situ and non-muscle invasive, non-metastatic (superficial) human urothelial ca
Externí odkaz:
https://doaj.org/article/30d7b27f36424170ac6476b7510440f5
Autor:
Anna L. Höving, Beatrice A. Windmöller, Cornelius Knabbe, Barbara Kaltschmidt, Christian Kaltschmidt, Johannes F. W. Greiner
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Stem cells of the neural crest (NC) vitally participate to embryonic development, but also remain in distinct niches as quiescent neural crest-derived stem cell (NCSC) pools into adulthood. Although NCSC-populations share a high capacity for self-ren
Externí odkaz:
https://doaj.org/article/29dceb30a32c40f1919d6a44eb2ecee5
Autor:
Y. Maurice Morillon, Claire Smalley Rumfield, Samuel T. Pellom, Ariana Sabzevari, Nicholas T. Roller, Lucas A. Horn, Caroline Jochems, Claudia Palena, John W. Greiner, Jeffrey Schlom
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The lack of serial biopsies in patients with a range of carcinomas has been one obstacle in our understanding of the mechanism of action of immuno-oncology agents as well as the elucidation of mechanisms of resistance to these novel therapeutics. Whi
Externí odkaz:
https://doaj.org/article/17c83c0e943345a1970124ea7637a98b
Autor:
Madlen Merten, Johannes F. W. Greiner, Tarek Niemann, Meike Grosse Venhaus, Daniel Kronenberg, Richard Stange, Dirk Wähnert, Christian Kaltschmidt, Thomas Vordemvenne, Barbara Kaltschmidt
Publikováno v:
Cells, Vol 11, Iss 5, p 823 (2022)
Female sex is increasingly associated with a loss of bone mass during aging and an increased risk of developing nonunion fractures. Hormonal factors and cell-intrinsic mechanisms are suggested to drive these sexual dimorphisms, although underlying mo
Externí odkaz:
https://doaj.org/article/8e869420784646b4a83e146e80d2aafd
Autor:
Barbara Kaltschmidt, Kaya E. Witte, Johannes F. W. Greiner, Florian Weissinger, Christian Kaltschmidt
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 261 (2022)
Among the cell populations existing within a tumor, cancer stem cells are responsible for metastasis formation and chemotherapeutic resistance. In the present review, we focus on the transcription factor NF-κB, which is present in every cell type in
Externí odkaz:
https://doaj.org/article/fe0354e883974da9af6ef19d3c44a471
Publikováno v:
Phys.Rev.C57:1938-1961,1998
A self-consistent relativistic integral-differential equation of the Boltzmann-Uehling-Uhlenbeck-type for the $N^{*}$(1440) resonance is developed based on an effective Lagrangian of baryons interacting through mesons. The closed time-path Green's fu
Externí odkaz:
http://arxiv.org/abs/nucl-th/9709047
Publikováno v:
Cells, Vol 10, Iss 8, p 2042 (2021)
NF-κB (nuclear factor kappa B) belongs to a family of transcription factors known to regulate a broad range of processes such as immune cell function, proliferation and cancer, neuroprotection, and long-term memory. Upcoming fields of NF-κB researc
Externí odkaz:
https://doaj.org/article/baf6fd5a3da047fe986d64c17b4de7da
Autor:
Anna L. Höving, Julian Schmitz, Kazuko E. Schmidt, Johannes F. W. Greiner, Cornelius Knabbe, Barbara Kaltschmidt, Alexander Grünberger, Christian Kaltschmidt
Publikováno v:
Biology, Vol 10, Iss 8, p 708 (2021)
Migratory capabilities of adult human stem cells are vital for assuring endogenous tissue regeneration and stem cell-based clinical applications. Although human blood serum has been shown to be beneficial for cell migration and proliferation, little
Externí odkaz:
https://doaj.org/article/549fd27b6f7e4286aa2b348b331de1d1