Výsledky vyhledávání

Myocardial gene transfer by selective pressure-regulated retroinfusion of coronary veins

Autor: H Katus, W Giehrl, R Hullin, D Heinrich, W.-M. Franz, G Baretton, Christian Kupatt, Gerhard Steinbeck, G von Degenfeld, Peter Boekstegers, G Middeler

Publikováno v: Gene Therapy. 7:232-240

Catheter-based percutaneous transluminal gene delivery (PTGD) into the coronary artery still falls behind the expectations of an efficient myocardial gene delivery system. In this study gene delivery was applied by selective pressure-regulated retroi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::908b62a92148831188d2e02283301281
https://doi.org/10.1038/sj.gt.3301079

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Targeting of dobutamine to ischemic myocardium without systemic effects by selective suction and pressure-regulated retroinfusion

Autor: Peter Boekstegers, G von Degenfeld, W Giehrl

Publikováno v: Cardiovascular Research. 35:233-240

Objective: To study the effects of low-dose dobutamine and/or glyceryl trinitrate in addition to selective suction and pressure-regulated retroinfusion with arterial blood on regional myocardial function of the ischemic myocardium and systemic hemody

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4757e2f46a52f3579fae808ace2dd567
https://doi.org/10.1016/s0008-6363(97)00126-0

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Retroinfusion-supported stenting in high-risk patients for percutaneous intervention and bypass surgery: results of the prospective randomized myoprotect I study

Autor: Tilmann Pohl, Gerhard Steinbeck, Stefan Paul, Christian Kupatt, Hermann Reichenspurner, W Giehrl, Peter Boekstegers, Philip Raake, Bruno Reichart

Publikováno v: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac AngiographyInterventions. 62(3)

The objective of this study was to assess event-free survival and total treatment costs of retroinfusion-supported stenting in high-risk patients compared to bypass surgery. An increasing number of patients with main-stem and main-stem-equivalent ste

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b75685ee9ed2355bffac43eb899d771
https://pubmed.ncbi.nlm.nih.gov/15224298

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Selective pressure-regulated retroinfusion of coronary veins as an alternative access of ischemic myocardium: implications for myocardial protection, myocardial gene transfer and angiogenesis

Autor: Gerhard Steinbeck, W.M. Franz, Christian Kupatt, W Giehrl, Peter Boekstegers, G von Degenfeld

Publikováno v: Zeitschrift fur Kardiologie. 89

There is renewed interest in the coronary venous system as an alternative access to ischemic myocardium. Selective pressure-regulated retroinfusion is a catheter-based approach which has been shown to increase the efficacy of retrograde oxygen delive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f19ab3cb3887af3d3355ef618991adb
https://pubmed.ncbi.nlm.nih.gov/11151777

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Comparison of Pura-Vario and Palmaz-Schatz stents following implantation using normal and high pressure in pigs: immediate and late results assessed by 3-dimensional IVUS

Autor: W Giehrl, D Heinrich, G von Degenfeld, Peter Boekstegers

Publikováno v: Zeitschrift fur Kardiologie. 88(11)

The Pura-Vario stent features 2 newly designed "bridging segments" for enhanced longitudinal flexibility, in order to allow easier and safer stent implantation.The aim of the present experimental investigation was to analyze the expansion characteris

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848945b6bf25719a7a4ddd17a6df6f91
https://pubmed.ncbi.nlm.nih.gov/10643058

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Selective suction and pressure-regulated retroinfusion: an effective and safe approach to retrograde protection against myocardial ischemia in patients undergoing normal and high risk percutaneous transluminal coronary angioplasty

Autor: Peter Boekstegers, Georges von Degenfeld, Gerhard Steinbeck, W Giehrl

Publikováno v: Journal of the American College of Cardiology. 31(7)

We sought to study the safety, feasibility and efficacy of selective suction and pressure-regulated retroinfusion to protect against myocardial ischemia in patients undergoing normal risk and high risk balloon angioplasty.In a pig model of acute myoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::855dc2397fc027b7f1e3d8951c76d7e7
https://pubmed.ncbi.nlm.nih.gov/9626830

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Subchronic exposure of cardiomyocytes to low concentrations of tumor necrosis factor alpha attenuates the positive inotropic response not only to catecholamines but also to cardiac glycosides and high calcium concentrations

Autor: Peter Boekstegers, Iris Kainz, Wolfgang Peter, Karl Werdan, W Giehrl

Publikováno v: Molecular and cellular biochemistry. 156(2)

The main purpose of this study was to determine the subchronic effects of low concentrations of tumor necrosis factor alpha (TNF alpha) on the inotropic response and on the cellular level of high energy phosphates of cardiomyocytes. Therefore, the in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d20e73dd5ed3bb46aef8b95f88bbb80c
https://pubmed.ncbi.nlm.nih.gov/9095470

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