Zobrazeno 1 - 10
of 38
pro vyhledávání: '"W GERALD ROBISON"'
Autor:
Mary Alice Crawford, Joram Piatigorsky, Shivalingappa K. Swamynathan, W. Gerald Robison, Jyotshnabala Kanungo
Publikováno v:
The FASEB Journal. 17:1996-2005
The water meniscus bisects the eyes of the “four-eyed” fish Anableps anableps, resulting in simultaneous vision in air and water. We compare the structure and macromolecular compositions of the Anableps dorsal (air) and ventral (water) corneas wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e400cd576832f3baa3d27fe8e5f1ca18
https://doi.org/10.1096/fj.03-0122com
https://doi.org/10.1096/fj.03-0122com
Publikováno v:
Experimental Eye Research. 75:603-609
Statins are commonly prescribed cholesterol-lowering agents which inhibit the rate-limiting enzyme of the cholesterol biosynthetic pathway. In addition to inhibiting cholesterol synthesis, statins also inhibit the synthesis of other sterol and non-st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c088ef39e7bdc8b4542d6924f5f796da
https://doi.org/10.1006/exer.2002.2053
https://doi.org/10.1006/exer.2002.2053
Autor:
Martin L. Katz, W. Gerald Robison
Publikováno v:
Archives of Gerontology and Geriatrics. 34:169-184
Lipofuscins, also known as age-pigments, have three defining characteristics: (1) they consist of intracellular secondary lysosomes; (2) they have a yellow autofluorescent emission when excited by near ultraviolet or blue light; and (3) they accumula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26989219def660469d9be90bcac3a338
https://doi.org/10.1016/s0167-4943(02)00005-5
https://doi.org/10.1016/s0167-4943(02)00005-5
Autor:
Eleonora Carosa, Peter J. Steinbach, Joseph Horwitz, Joram Piatigorsky, W. Gerald Robison, Ernst R. Tamm, Zbynek Kozmik, Linlin Ding
Publikováno v:
Journal of Biological Chemistry. 275:41064-41073
While many of the diverse crystallins of the transparent lens of vertebrates are related or identical to metabolic enzymes, much less is known about the lens crystallins of invertebrates. Here we investigate the complex eye of scallops. Electron micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dada231fa2470a42b9e9de8f88739329
https://doi.org/10.1074/jbc.m005625200
https://doi.org/10.1074/jbc.m005625200
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 16:167-172
The purpose of this study was to determine whether capillary dilation is one of the earliest structural changes in the diabetic-like retinopathy of the galactose-fed rat model and thus may represent a stage where intervention treatment might still be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3fbdd6f52a8c1f30fc1813b738f5692
https://doi.org/10.1089/jop.2000.16.167
https://doi.org/10.1089/jop.2000.16.167
Publikováno v:
Journal of Diabetes and its Complications. 12:28-33
Hyperglycemia plays a primary causal role in the early vascular damage leading to diabetic retinopathy, but the intermediate biochemical mechanisms involved are not known. Because albumin modified by Amadori glucose adducts has been implicated in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a49e5eb3558facbb2040d6a01b4b743f
https://doi.org/10.1016/s1056-8727(97)00051-2
https://doi.org/10.1016/s1056-8727(97)00051-2
Autor:
Morton F. Goldberg, Debasish Sinha, Cheng Zhang, W. Gerald Robison, Paul Russell, Madhumita Ghosh, J. Samuel Zigler, Stacey Hose, Rachel Neal, Olof H. Sundin, Woo-Kuen Lo, Terrence P. O'Brien
Publikováno v:
Experimental eye research. 80(3)
We have discovered a spontaneous mutation in the Sprague-Dawley rat with a novel eye phenotype that we have named Nuc1. The Nuc1 mutation behaves as a single semi-dominant locus with an intermediate phenotype in the heterozygotes. Heterozygotes exhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a220b4642e070d3222bd0b7e0eb47d2
https://pubmed.ncbi.nlm.nih.gov/15721615
https://pubmed.ncbi.nlm.nih.gov/15721615
Publikováno v:
Journal of cell science. 116(Pt 11)
The Pax6 transcription factor functions early during embryogenesis to control key steps in brain, pancreas, olfactory and ocular system development. A requirement for Pax6 in proper formation of lens, iris and retina is well documented. By examining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57863ff2931d177b220e73cf189a559c
https://pubmed.ncbi.nlm.nih.gov/12692153
https://pubmed.ncbi.nlm.nih.gov/12692153
Publikováno v:
Molecular and cellular biology. 22(3)
We have constructed an ALDH3a1 null mouse to investigate the role of this enzyme that comprises nearly one-half of the total water-soluble protein in the mouse corneal epithelium. ALDH3a1-deficient mice are viable and fertile, have a corneal epitheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f7f63c62d684f6057ba1c202ddb8c48
https://pubmed.ncbi.nlm.nih.gov/11784860
https://pubmed.ncbi.nlm.nih.gov/11784860
Autor:
Debasish Sinha, Cynthia Jaworski, W. Gerald Robison, Jack Favor, Mary Lyon, Caroline Thaung, Graeme Wistow, Christine Slingsby, M. Keith Wyatt, Lewis K. Pannell, Robert Sarra
Publikováno v:
The Journal of biological chemistry. 276(12)
In Opj, an inherited cataract in mice, opacity is associated with a mutation in Crygs, the gene for gammaS-crystallin, the first mutation to be associated with this gene. A single base change causes replacement of Phe-9, a key hydrophobic residue in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9e63ef63878bdce8c4899d0e57ca188
https://pubmed.ncbi.nlm.nih.gov/11121426
https://pubmed.ncbi.nlm.nih.gov/11121426