Zobrazeno 1 - 10
of 16
pro vyhledávání: '"W G Kirlin"'
Publikováno v:
Evidence Based Validation of Traditional Medicines ISBN: 9789811581267
Medicinal herbs are extensively used for therapy in many parts of the world. This traditional knowledge has been passed on from one generation to the other, based on their long-term clinical use. Little clinical and experimental data is available for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::344999ea1878cac351172b4a9ca4d2a3
https://doi.org/10.1007/978-981-15-8127-4_30
https://doi.org/10.1007/978-981-15-8127-4_30
Autor:
Anne Ramsey, Uriel Blas-Machado, Yan Fengxia, Alec J. Davidson, Sunny Onyeabor, Shakyra Richardson, Stephanie R. Lundy, W G Kirlin, Yusuf Omosun, Qing He, Lilly Cheng Immergluck, Francis O. Eko, Carolyn M. Black, Debra Ellerson, Winston E. Thompson, Joseph U. Igietseme, Jason P. DeBruyne
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-2 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de69bb67b10954119c3471edbfc8e890
https://doaj.org/article/958f204d0cfa43c78ef27cc51acdfad3
https://doaj.org/article/958f204d0cfa43c78ef27cc51acdfad3
Publikováno v:
International Journal of Molecular Sciences, Vol 3, Iss 10, Pp 1027-1038 (2002)
International Journal of Molecular Sciences
Volume 3
Issue 10
Pages 1027-1038
International Journal of Molecular Sciences
Volume 3
Issue 10
Pages 1027-1038
The risk from chemical carcinogens and environmental toxins is dependent on the metabolic balance between bioactivation and detoxification enzymes. Therefore, agents that alter enzyme expression are critical factors in toxicity. Enhancement or suppre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8343b8e777297ac77922f0ba9f4f0069
https://doi.org/10.3390/i3101027
https://doi.org/10.3390/i3101027
Publikováno v:
The Journal of Nutrition. 132:2303-2306
Glutathione (GSH) has a central role in the maintenance of the thiol-disulfide redox state in mammalian cells. GSH synthesis can be physiologically limited by the availability of cysteine (Cys), and Cys and its precursors are variable in the human di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bab1205077da971d73296791e1de607
https://doi.org/10.1093/jn/132.8.2303
https://doi.org/10.1093/jn/132.8.2303
Publikováno v:
Immunopharmacology and Immunotoxicology. 21:379-396
Childhood cancer has been increasing significantly over the past two decades in the United States, suggesting that environmental exposures may be playing a causative role. One such cause may be maternal smoking during pregnancy. Suspected carcinogens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a5bdd5c8dcb0b1799d4970373f1da5
https://doi.org/10.3109/08923979909052769
https://doi.org/10.3109/08923979909052769
Publikováno v:
Immunopharmacology and Immunotoxicology. 18:309-321
The ability of the polycyclic aromatic hydrocarbon (PAH), benzo[a]pyrene (BP) and its metabolites to be immunosuppressive has been well documented by many investigators. The arylamine, 2-aminofluorene (AF) and its metabolic intermediates have not bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5828ff5e4c54116306065364f9354eb9
https://doi.org/10.3109/08923979609052738
https://doi.org/10.3109/08923979609052738
Autor:
Jose W. Rodriguez, Paul Urso, Katherine Kemp, W G Kirlin, Timothy D. Rustan, Mark E. Lee, Kevin Gray, Ronald J. Ferguson, Mark A. Doll, David W. Hein
Publikováno v:
Archives of Toxicology. 67:445-452
Polymorphic expression of arylamine N-acetyltransferase (EC 2.3.1.5) may be a differential risk factor in metabolic activation of arylamine carcinogens and susceptibility to cancers related to arylamine exposures. Human epidemiological studies sugges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66938b9047889aaf9eab1cb11955c0f
https://doi.org/10.1007/bf01969914
https://doi.org/10.1007/bf01969914
Publikováno v:
Nutrition and cancer. 61(3)
Cancer prevention by dietary phytochemicals has been shown to involve decreased cell proliferation and cell cycle arrest. However, there is limited understanding of the mechanisms involved. Previously, we have shown that a common effect of phytochemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3630281c75333e4a49e16566497fcf7a
https://pubmed.ncbi.nlm.nih.gov/19373606
https://pubmed.ncbi.nlm.nih.gov/19373606
Autor:
Allen F. Andrews, David W. Hein, Tokunbo Yerokun, Toni Y. Minor, A Trinidad, Robert H. Heflich, Ronald J. Ferguson, W G Kirlin, Fredrick Ogolla
Publikováno v:
Mutagenesis. 5:233-240
The genetic constitution of mammalian enzymes involved in the metabolism of xenobiotics is one of the important factors responsible for large inter-individual differences in the rate of biotransformation and consequently the magnitude of genotoxic ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52bd7803fbb3c3219200f410b7a99282
https://doi.org/10.1093/mutage/5.3.233
https://doi.org/10.1093/mutage/5.3.233
Autor:
Thomas R. Ziegler, Corinna L. Anderson, W G Kirlin, Dean P. Jones, Young-Mi Go, Joseph M. Kinkade
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 18(11)
Redox mechanisms function in control of gene expression, cell proliferation, and apoptosis, but the circuitry for redox signaling remains unclear. Cysteine and methionine are the only amino acids in proteins that undergo reversible oxidation/reductio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31bae439d3ad1601153f9e2323f84e0a
https://pubmed.ncbi.nlm.nih.gov/15180957
https://pubmed.ncbi.nlm.nih.gov/15180957