Zobrazeno 1 - 10
of 98
pro vyhledávání: '"W G, Nayler"'
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 19:79-87
1. The postulate that the composition of solutions used to reperfuse ischaemic hearts may modulate their ability to synthesize high-energy compounds was tested in isolated rat hearts subjected to 30 min normothermic ischaemia and then reperfused with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d689e5d67cb677769c279a0b2e40ed
https://doi.org/10.1111/j.1440-1681.1992.tb00425.x
https://doi.org/10.1111/j.1440-1681.1992.tb00425.x
Autor:
W. G. Nayler, J. S. Dillon
Publikováno v:
European Journal of Clinical Pharmacology. 39:S13-S16
Ischaemia imposes a progression of damage on the myocardium, starting with a loss of adenosine triphosphate, creatine phosphate, potassium and active tension-generating capacity. These changes progress until the tissue is incapable of maintaining ion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25737303604ba829b0d5b11600e735f6
https://doi.org/10.1007/bf03216269
https://doi.org/10.1007/bf03216269
Autor:
W. G. Nayler, J. S. Dillon
Publikováno v:
European Journal of Clinical Pharmacology. 39:S13-S16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4983090b50c0be8c53387d994fb5674
https://doi.org/10.1007/bf01409201
https://doi.org/10.1007/bf01409201
Autor:
W. G. Nayler, T. Toyo-Oka
Publikováno v:
Blood pressure. 5(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa30082d82d114314936dd6edcbf5f2
https://pubmed.ncbi.nlm.nih.gov/8973757
https://pubmed.ncbi.nlm.nih.gov/8973757
Autor:
W G, Nayler
Publikováno v:
American journal of hypertension. 7(10 Pt 2)
Recent advances in the field of calcium antagonism include the development of long-acting calcium antagonists, some of which have a slow onset of action. Some of these newly developed calcium antagonists are dihydropyridine derivatives. Others, inclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::425619a649dcb0cf8267c65d0dabe501
https://pubmed.ncbi.nlm.nih.gov/7826562
https://pubmed.ncbi.nlm.nih.gov/7826562
Autor:
W G, Nayler
Publikováno v:
Basic research in cardiology. 89
Atherosclerosis is a multifactorial disease which culminates in the ruptured plaque seen at autopsy. Hypercholesterolaemia, subintimal accumulation of lipid, monocyte adhesion followed by penetration across the endothelium, the conversion of monocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b6419215d83884f1a4c2b8a725db3baa
https://pubmed.ncbi.nlm.nih.gov/7945168
https://pubmed.ncbi.nlm.nih.gov/7945168
Publikováno v:
Journal of cardiovascular pharmacology. 19(5)
To establish whether the density, affinity, or selectivity of endothelin-1 (ET-1) binding sites in cardiac ventricular membranes varies with age, membranes were harvested from 5- to 7-day-, 20-day-, and 8- to 9-week-old Sprague Dawley rats and labele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a0dd58898074ff0f24608f9d366ac37a
https://pubmed.ncbi.nlm.nih.gov/1381775
https://pubmed.ncbi.nlm.nih.gov/1381775
Autor:
W G, Nayler
Publikováno v:
Journal of cardiovascular pharmacology. 20
Oxy and hydroxy radicals produced during postischemic reperfusion may contribute to the mechanisms responsible for the sustained contractile dysfunction and ultrastructural injury that occur under these conditions. At the molecular level, the consequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c66d141544f0bace411d74b5270ef5a9
https://pubmed.ncbi.nlm.nih.gov/1282608
https://pubmed.ncbi.nlm.nih.gov/1282608
Autor:
W G, Nayler, X H, Gu
Publikováno v:
Journal of human hypertension. 5
Amlodipine is a 'second generation', long-acting calcium antagonist. To characterise the binding properties of this drug saturation binding studies were undertaken using (-)[3H]amlodipine and rat cardiac membrane fragments. (-)[3H]Amlodipine bound to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e84767516e5afe0d84015eafeaf08272
https://pubmed.ncbi.nlm.nih.gov/1834847
https://pubmed.ncbi.nlm.nih.gov/1834847
Autor:
R D, Tanz, W G, Nayler
Publikováno v:
Archives internationales de pharmacodynamie et de therapie. 312
Acetylcholine elicited an increase in developed tension on isolated porcine coronary arterial rings at concentrations exceeding 1.1 x 10(-7) M. However, at concentrations greater than 3.3 x 10(-6) M, desensitization occurred with repeated exposures t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::953233c44ab1c3fccf95bff1be0950ba
https://pubmed.ncbi.nlm.nih.gov/1663335
https://pubmed.ncbi.nlm.nih.gov/1663335