Zobrazeno 1 - 10
of 15
pro vyhledávání: '"W G, Cance"'
Publikováno v:
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. 15(6)
Aim The morbidity of anastomotic dehiscence may be mitigated by a defunctioning stoma, but it is unclear if it is required for most low rectal anastomoses. Preoperative risk factors leading to anastomotic complications and the indications for faecal
Autor:
W G, Cance
Publikováno v:
Breast disease. 12
Publikováno v:
The Journal of biological chemistry. 275(39)
The focal adhesion kinase (FAK) is a mediator of cell-extracellular matrix signaling events and is overexpressed in tumor cells. In order to rapidly down-regulate FAK function in normal and transformed mammary cells, we have used adenoviral gene tran
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(6)
The focal adhesion kinase (FAK) is a protein tyrosine kinase linked to signaling events between cells and the extracellular matrix. Studies at the Western blot level have demonstrated up-regulation of FAK expression in invasive breast and colon cance
Publikováno v:
Cancer. 88(4)
The Commission on Cancer data from the National Cancer Data Base (NCDB) has previously reported data evaluating time trends in various cancers, including such elements as stage of disease at diagnosis, treatment, and survival for multiple tumor sites
Publikováno v:
Cancer. 86(8)
Focal adhesion kinase (FAK) is a tyrosine kinase that is important to such key functions such as cell adhesion, motility, and invasion. A MEDLINE search of the years 1980-1998 found no previous reports of FAK expression in human ovarian carcinoma. Th
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 9(12)
Focal adhesion kinase (FAK) is a tyrosine kinase that is linked to signaling pathways between cells and their extracellular matrix. An alternate transcript of the COOH-terminal region of the FAK gene, called FAK-related nonkinase, has been shown to a
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 7(4)
The focal adhesion kinase (FAK) is a nonreceptor protein tyrosine kinase implicated in integrin-mediated signal transduction pathways, oncogenic transformation by v-src, and the invasion of human tumors. The overexpression of p125FAK in a variety of
Publikováno v:
Cancer research. 55(18)
Rak is a nuclear tyrosine kinase containing Src homology 2 and 3 domains at its NH2 terminus. We report here that the retinoblastoma tumor susceptibility gene product pRb associates with Rak in vivo and in vitro. Rak binds in the A/B pocket region of
Publikováno v:
Cancer research. 55(13)
The focal adhesion kinase (FAK) gene encodes a tyrosine kinase (p125FAK) thought to be involved in signal transduction pathways used in cell adhesion, motility, and anchorage-independent growth. Because alterations in these cellular processes occur i