Zobrazeno 1 - 10
of 1 144
pro vyhledávání: '"W Fawcett"'
Autor:
Jiri Ruzicka, Marketa Dalecka, Kristyna Safrankova, Diego Peretti, Pavla Jendelova, Jessica C. F. Kwok, James W. Fawcett
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Perineuronal nets (PNNs) enwrap mature neurons, playing a role in the control of plasticity and synapse dynamics. PNNs have been shown to have effects on memory formation, retention and extinction in a variety of animal models. It has been p
Externí odkaz:
https://doaj.org/article/50eda852b9e34524b993f97aead30346
Autor:
Jana Dubisova, Jana Svobodova Burianova, Lucie Svobodova, Pavol Makovicky, Noelia Martinez-Varea, Anda Cimpean, James W. Fawcett, Jessica C.F. Kwok, Sarka Kubinova
Publikováno v:
Brain Research Bulletin, Vol 181, Iss , Pp 144-156 (2022)
Hyaluronan (HA) is a core constituent of perineuronal nets (PNNs) that surround subpopulations of neurones. The PNNs control synaptic stabilization in both the developing and adult central nervous system, and disruption of PNNs has shown to reactivat
Externí odkaz:
https://doaj.org/article/ec29846fa3324243b3e954a5662e5c61
Autor:
Julien Di Giovanni, Tim W. Fawcett, Christopher N. Templeton, Shubhi Raghav, Neeltje J. Boogert
Publikováno v:
Frontiers in Ecology and Evolution, Vol 10 (2022)
Rapid population growth and the urbanization of modern environments are markedly increasing human-wildlife conflict. Wild animals in urban landscapes can benefit from exploiting human resources, but are also exposed to increased risk of human-caused
Externí odkaz:
https://doaj.org/article/8af80f0b10ed4aec937c751520f87413
Publikováno v:
ACS Omega, Vol 6, Iss 17, Pp 11223-11230 (2021)
Externí odkaz:
https://doaj.org/article/ed789ea3174d43af9d521b58fa863636
Autor:
James W. Fawcett, Jessica C. F. Kwok
Publikováno v:
Frontiers in Integrative Neuroscience, Vol 16 (2022)
Chondroitin sulphate and heparan sulphate proteoglycans (CSPGS and HSPGs) are found throughout the central nervous system (CNS). CSPGs are ubiquitous in the diffuse extracellular matrix (ECM) between cells and are a major component of perineuronal ne
Externí odkaz:
https://doaj.org/article/a4ebdd7202b84d35840baf71d3d9af94
Autor:
Veselina Petrova, Craig S. Pearson, Jared Ching, James R. Tribble, Andrea G. Solano, Yunfei Yang, Fiona M. Love, Robert J. Watt, Andrew Osborne, Evan Reid, Pete A. Williams, Keith R. Martin, Herbert M. Geller, Richard Eva, James W. Fawcett
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Increasing the supply of growth machinery to axons is a potential strategy for promoting repair after injury. Here the authors demonstrate that the endoplasmic reticulum adaptor molecule Protrudin provides cellular components that support axonal rege
Externí odkaz:
https://doaj.org/article/719ad1bd15824dbeb84c041f6d0b9924
Autor:
Bart Nieuwenhuis, Amanda C Barber, Rachel S Evans, Craig S Pearson, Joachim Fuchs, Amy R MacQueen, Susan van Erp, Barbara Haenzi, Lianne A Hulshof, Andrew Osborne, Raquel Conceicao, Tasneem Z Khatib, Sarita S Deshpande, Joshua Cave, Charles Ffrench‐Constant, Patrice D Smith, Klaus Okkenhaug, Britta J Eickholt, Keith R Martin, James W Fawcett, Richard Eva
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 8, Pp 1-24 (2020)
Abstract Peripheral nervous system (PNS) neurons support axon regeneration into adulthood, whereas central nervous system (CNS) neurons lose regenerative ability after development. To better understand this decline whilst aiming to improve regenerati
Externí odkaz:
https://doaj.org/article/774319b15576431a80d815b1901eaee3
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Spinal cord interneurons (SpINs) are highly diverse population of neurons that play a significant role in circuit reorganization and spontaneous recovery after spinal cord injury. Regeneration of SpIN axons across rodent spinal injuries has been demo
Externí odkaz:
https://doaj.org/article/4a6727406e7244c1987ba6962435d825
Autor:
Jennifer N. Dulin, Andrew F. Adler, Hiromi Kumamaru, Gunnar H. D. Poplawski, Corinne Lee-Kubli, Hans Strobl, Daniel Gibbs, Ken Kadoya, James W. Fawcett, Paul Lu, Mark H. Tuszynski
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Understanding how transplanted cells interact with the host nervous system will be important for cell based neural regeneration approaches. Here, the authors study the sensory fate of neural progenitor cell grafts transplanted to the injured spinal c
Externí odkaz:
https://doaj.org/article/7f9b4eafb46245958438aafcbd21521f
Autor:
Heleen M. Van’t Spijker, Dáire Rowlands, Jean Rossier, Barbara Haenzi, James W. Fawcett, Jessica C. F. Kwok
Publikováno v:
Neural Plasticity, Vol 2019 (2019)
The perineuronal net (PNN) is a mesh-like proteoglycan structure on the neuronal surface which is involved in regulating plasticity. The PNN regulates plasticity via multiple pathways, one of which is direct regulation of synapses through the control
Externí odkaz:
https://doaj.org/article/b6863ec9885c4fce8c835836a3d92d17