Zobrazeno 1 - 10
of 25
pro vyhledávání: '"W F, Marzluff"'
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 279:G471-G476
There are several independent metabolic steps that determine the level of a protein in eukaryotic cells. The steady-state level of the mRNA encoding the specific protein is determined by rate of transcription, percentage of transcripts that are ultim
Publikováno v:
Proceedings of the National Academy of Sciences. 93:8852-8857
Few promoters are active at high levels in all cells. Of these, the majority encode structural RNAs transcribed by RNA polymerases I or III and are not accessible for the expression of proteins. An exception are the small nuclear RNAs (snRNAs) transc
Publikováno v:
Genome Research. 6:688-701
The histone gene cluster on mouse chromosome 13 has been isolated and characterized. Using overlapping YAC clones containing histone genes from chromosome 13, a contig of approximately 2 Mb has been defined. It contains 45 histone genes, organized in
Publikováno v:
Genome Research. 6:702-714
The histone gene cluster on mouse chromosome 3 has been isolated as a series of overlapping P1 clones, covering 110-120 kb, by probing with the histone H3-614 gene that had been mapped previously to mouse chromosome 3. There are genes for 10 core his
Autor:
W F Marzluff, Ronald W. DeBry
Publikováno v:
Genetics. 138:191-202
Selection promoting differential use of synonymous codons has been shown for several unicellular organisms and for Drosophila, but not for mammals. Selection coefficients operating on synonymous codons are likely to be extremely small, so that a very
Autor:
Z, Dominski, W F, Marzluff
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 177
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 279(3)
There are several independent metabolic steps that determine the level of a protein in eukaryotic cells. The steady-state level of the mRNA encoding the specific protein is determined by rate of transcription, percentage of transcripts that are ultim
Publikováno v:
Nucleic acids symposium series. (33)
Histone mRNAs are the only non-polyadenylated mRNAs, ending in a conserved 26 nt sequence which can form a stem-loop. It has not been possible to make histone mRNAs with mutant stem-loops since most mutations in the stem-loop interfere with the 3' pr
Publikováno v:
Nucleic acids symposium series. (33)
Histone mRNAs end in a conserved 26 nt sequence which can form a stem-loop with a six-base stem and a four base loop. The 3' end of histone mRNA functions in the nucleus in pre-mRNA processing and mRNA transport and in the cytoplasm in translation an
Autor:
D R, Pilch, W F, Marzluff
Publikováno v:
Gene expression. 1(1)
Chimeric genes which fuse the mouse histone H2a gene and the mouse U1b gene were constructed and introduced into CHO cells by cotransfection. In the UH genes, the U1b gene promoter and the start of the Ulb gene were fused to the H2a gene in the 5′