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Induction of secretory immunity with bioadhesive poly (D,L-lactide-co-glycolide) microparticles containingStreptococcus sobrinusglucosyltransferase

Autor: Donald L. Wise, D. J. Smith, P. H. Fackler, V. L. De Souza, Debra J. Trantolo, E. J. Gusek, Joseph D. Gresser, W. F. King

Publikováno v: Oral Microbiology and Immunology. 15:124-130

The effect of mucosal delivery of Streptococcus sobrinus glucosyltransferase (GTF) in bioadhesive poly ( d,l-lactide-co-glycolide) (PLGA) microparticles on induction of salivary IgA and serum IgG antibody responses was measured in Sprague-Dawley rats

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e89403285efc12dd1509715315474bc
https://doi.org/10.1034/j.1399-302x.2000.150209.x

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System R: An architectural overview

Autor: G. R. Putzolu, W. F. King, J. W. Mehl, Jim Gray, P. G. Sellinger, H. R. Strong, B. W. Wade, Donald D. Chamberlin, Irving L. Traiger, Robert A. Yost, Bruce G. Lindsay, Donald R. Slutz, Raymond A. Lorie, M. W. Blasgen, Morton M. Astrahan, Mario Schkolnick, T. G. Price

Publikováno v: IBM Systems Journal. 38:375-396

We have described the architecture of System R, including the Relational Data System and the Research Storage System. The RDS supports a flexible spectrum of binding times, ranging from precompilation of “canned transactions” to on-line execution

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e753f6e8f2a61c8073346ed5da2b7f5f
https://doi.org/10.1147/sj.382.0375

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Immunological and microbiologic changes during caries development in young children

Autor: Cristiane Duque, Daniel J. Smith, Thaís Manzano Parisotto, Marinês Nobre-dos-Santos, Renata O. Mattos-Graner, Carolina Steiner-Oliveira, W F King

Publikováno v: Caries research. 45(4)

We explored the association between caries development, colonization with caries-associated microflora, and immunity as children begin the transition to mixed dentition. Forty children received dental examinations at 3–4 years of age, repeated a ye

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c885e69e127001b60e6a27492416f0d
https://pubmed.ncbi.nlm.nih.gov/21822016

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Remote glucosyltransferase-microparticle vaccine delivery induces protective immunity in the oral cavity

Autor: D J, Smith, A, Lam, L A, Barnes, W F, King, Z, Peacock, D L, Wise, D J, Trantolo, M A, Taubman

Publikováno v: Oral microbiology and immunology. 18(4)

Intranasally administered dental caries vaccines show significant promise for human application. Alternate mucosal routes may be required, however, to induce caries-protective salivary IgA antibody in children with respiratory diseases. Since rectal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bcf9a4d36dae81ce3a235477ae9645bf
https://pubmed.ncbi.nlm.nih.gov/12823800

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Induction of secretory immunity with bioadhesive poly (D,L-lactide-co-glycolide) microparticles containing Streptococcus sobrinus glucosyltransferase

Autor: D J, Smith, D J, Trantolo, W F, King, E J, Gusek, P H, Fackler, J D, Gresser, V L, De Souza, D L, Wise

Publikováno v: Oral microbiology and immunology. 15(2)

The effect of mucosal delivery of Streptococcus sobrinus glucosyltransferase (GTF) in bioadhesive poly (D,L-lactide-co-glycolide) (PLGA) microparticles on induction of salivary IgA and serum IgG antibody responses was measured in Sprague-Dawley rats.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9a2fd7af045d0628b3073f14de83a2eb
https://pubmed.ncbi.nlm.nih.gov/11155176

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Structural integrity of infant salivary immunoglobulin A (IgA) in IgA1 protease-rich environments

Autor: Martin A. Taubman, D. J. Smith, J. V. Gilbert, W. F. King

Publikováno v: Oral microbiology and immunology. 13(2)

IgA1 protease-secreting Streptococcus mitis often dominate the oral flora of the neonate and young infant at a time when salivary IgA concentrations are low and usually enriched in the secretory IgA1 subclass. To study the possible influence of these

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a59679d19e9947df30bf663fc799b3e
https://pubmed.ncbi.nlm.nih.gov/9573799

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Salivary IgA antibody to oral streptococcal antigens in predentate infants

Autor: D. J. Smith, W. F. King, Martin A. Taubman

Publikováno v: Oral microbiology and immunology. 5(2)

Salivary IgA antibodies to oral streptococci which colonize the infant oral cavity soon after birth were analyzed in 53 whole salivas of 17 infants who were between three and 27 weeks old. Antibody activities to Streptococcus mitis cells were detecte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d44edf0646c86243327e5d0fa07e179c
https://pubmed.ncbi.nlm.nih.gov/2087350

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