Zobrazeno 1 - 10
of 155
pro vyhledávání: '"W Edward Visser"'
Autor:
Luca Persani, Patrice Rodien, Carla Moran, W Edward Visser, Stefan Groeneweg, Robin Peeters, Samuel Refetoff, Mark Gurnell, Paolo Beck-Peccoz, Krishna Chatterjee
Publikováno v:
European Thyroid Journal, Vol 13, Iss 4, Pp 1-22 (2024)
Impaired sensitivity to thyroid hormones encompasses disorders with defective transport of hormones into cells, reduced hormone metabolism, and resistance to hormone action. Mediated by heritable single-gene defects, these rare conditions exhibit dif
Externí odkaz:
https://doaj.org/article/53795c768fc7468e908f81653ebe1894
Autor:
Sander Barnhoorn, Marcel E Meima, Robin P Peeters, Veerle M Darras, Selmar Leeuwenburgh, Jan H J Hoeijmakers, Wilbert P Vermeij, W Edward Visser
Publikováno v:
European Thyroid Journal, Vol 12, Iss 6, Pp 1-10 (2023)
Background: Thyroid hormone signaling is essential for development, metabolism, and response to stress but declines during aging, the cause of which is unknown. DNA damage accumulating with time is a main cause of aging, driving many age-related dise
Externí odkaz:
https://doaj.org/article/f7af7f3f184c4cbe9795ae267498776b
Autor:
Caroline M J van Kinschot, Ivona Lončar, Tessa M van Ginhoven, W Edward Visser, Robin P Peeters, Charlotte van Noord
Publikováno v:
European Thyroid Journal, Vol 12, Iss 6, Pp 1-12 (2023)
Objective: Evidence-based treatment guidelines for the management of postthyroidectomy hypocalcemia are absent. The aim of this study was to evaluate a newly developed symptom-based treatment algorithm including a protocolized attempt to phase out su
Externí odkaz:
https://doaj.org/article/a494c61bff7c44b7bab55e12e1fbcaf8
Autor:
Zhongli Chen, Robin P Peeters, Wesley Flach, Linda J de Rooij, Sena Yildiz, Alexander Teumer, Matthias Nauck, Rosalie B T M Sterenborg, Joost H W Rutten, Marco Medici, W Edward Visser, Marcel E Meima
Publikováno v:
European Thyroid Journal, Vol 12, Iss 4, Pp 1-11 (2023)
Objective: Thyroid hormone (TH) transport represents a critical first step in governing intracellular TH regulation. It is still unknown whether the full repertoire of TH transporters has been identified. Members of the solute carrier (SLC) 22 family
Externí odkaz:
https://doaj.org/article/2c1f801385674dea9938bb3ac518f358
Autor:
Elske T Massolt, Layal Chaker, Theo J Visser, Ad J M Gillis, Lambert C J Dorssers, Carolien M Beukhof, Boen L R Kam, Gaston J Franssen, Giulia Brigante, Tessa M van Ginhoven, W Edward Visser, Leendert H J Looijenga, Robin P Peeters
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0194259 (2018)
Levothyroxine replacement treatment in hypothyroidism is unable to restore physiological thyroxine and triiodothyronine concentrations in serum and tissues completely. Normal serum thyroid stimulating hormone (TSH) concentrations reflect only pituita
Externí odkaz:
https://doaj.org/article/862dba42207647b4a33a87508098fdfa
Autor:
Carolien M Beukhof, Marco Medici, Annewieke W van den Beld, Birgit Hollenbach, Antonia Hoeg, W Edward Visser, Wouter W de Herder, Theo J Visser, Lutz Schomburg, Robin P Peeters
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152748 (2016)
OBJECTIVE:It is still a matter of debate if subtle changes in selenium (Se) status affect thyroid function tests (TFTs) and bone mineral density (BMD). This is particularly relevant for the elderly, whose nutritional status is more vulnerable. DESIGN
Externí odkaz:
https://doaj.org/article/526fb6b6a6b7432ebc6f327ad49b1ed7
Autor:
W Edward Visser, Cíntia R Bombardieri, Chantal Zevenbergen, Sander Barnhoorn, Alexandre Ottaviani, Ingrid van der Pluijm, Renata Brandt, Ellen Kaptein, Ramona van Heerebeek, Hans van Toor, George A Garinis, Robin P Peeters, Marco Medici, Willy van Ham, Wilbert P Vermeij, Monique C de Waard, Ronald R de Krijger, Anita Boelen, Joan Kwakkel, John J Kopchick, Edward O List, Joost P M Melis, Veerle M Darras, Martijn E T Dollé, Gijsbertus T J van der Horst, Jan H J Hoeijmakers, Theo J Visser
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0149941 (2016)
DNA damage contributes to the process of aging, as underscored by premature aging syndromes caused by defective DNA repair. Thyroid state changes during aging, but underlying mechanisms remain elusive. Since thyroid hormone (TH) is a key regulator of
Externí odkaz:
https://doaj.org/article/ca420b0d4f254e4db9aa43c0a8d08565
Autor:
Elske T Massolt, Grigoris Effraimidis, Tim I M Korevaar, Wilmar M Wiersinga, W Edward Visser, Robin P Peeters, Hemmo A Drexhage
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153892 (2016)
Subjects at risk for major mood disorders have a higher risk to develop autoimmune thyroid disease (AITD) and vice-versa, implying a shared pathogenesis. In mood disorder patients, an abnormal profile of hematopoietic/neuronal growth factors is obser
Externí odkaz:
https://doaj.org/article/0fd9df1e6d78499886c464260d5aaed1
Autor:
Marco Medici, Eleonora Porcu, Giorgio Pistis, Alexander Teumer, Suzanne J Brown, Richard A Jensen, Rajesh Rawal, Greet L Roef, Theo S Plantinga, Sita H Vermeulen, Jari Lahti, Matthew J Simmonds, Lise Lotte N Husemoen, Rachel M Freathy, Beverley M Shields, Diana Pietzner, Rebecca Nagy, Linda Broer, Layal Chaker, Tim I M Korevaar, Maria Grazia Plia, Cinzia Sala, Uwe Völker, J Brent Richards, Fred C Sweep, Christian Gieger, Tanguy Corre, Eero Kajantie, Betina Thuesen, Youri E Taes, W Edward Visser, Andrew T Hattersley, Jürgen Kratzsch, Alexander Hamilton, Wei Li, Georg Homuth, Monia Lobina, Stefano Mariotti, Nicole Soranzo, Massimiliano Cocca, Matthias Nauck, Christin Spielhagen, Alec Ross, Alice Arnold, Martijn van de Bunt, Sandya Liyanarachchi, Margit Heier, Hans Jörgen Grabe, Corrado Masciullo, Tessel E Galesloot, Ee M Lim, Eva Reischl, Peter J Leedman, Sandra Lai, Alessandro Delitala, Alexandra P Bremner, David I W Philips, John P Beilby, Antonella Mulas, Matteo Vocale, Goncalo Abecasis, Tom Forsen, Alan James, Elisabeth Widen, Jennie Hui, Holger Prokisch, Ernst E Rietzschel, Aarno Palotie, Peter Feddema, Stephen J Fletcher, Katharina Schramm, Jerome I Rotter, Alexander Kluttig, Dörte Radke, Michela Traglia, Gabriela L Surdulescu, Huiling He, Jayne A Franklyn, Daniel Tiller, Bijay Vaidya, Tim de Meyer, Torben Jørgensen, Johan G Eriksson, Peter C O'Leary, Eric Wichmann, Ad R Hermus, Bruce M Psaty, Till Ittermann, Albert Hofman, Emanuele Bosi, David Schlessinger, Henri Wallaschofski, Nicola Pirastu, Yurii S Aulchenko, Albert de la Chapelle, Romana T Netea-Maier, Stephen C L Gough, Henriette Meyer Zu Schwabedissen, Timothy M Frayling, Jean-Marc Kaufman, Allan Linneberg, Katri Räikkönen, Johannes W A Smit, Lambertus A Kiemeney, Fernando Rivadeneira, André G Uitterlinden, John P Walsh, Christa Meisinger, Martin den Heijer, Theo J Visser, Timothy D Spector, Scott G Wilson, Henry Völzke, Anne Cappola, Daniela Toniolo, Serena Sanna, Silvia Naitza, Robin P Peeters
Publikováno v:
PLoS Genetics, Vol 10, Iss 2, p e1004123 (2014)
Autoimmune thyroid diseases (AITD) are common, affecting 2-5% of the general population. Individuals with positive thyroid peroxidase antibodies (TPOAbs) have an increased risk of autoimmune hypothyroidism (Hashimoto's thyroiditis), as well as autoim
Externí odkaz:
https://doaj.org/article/6d824980694a4a48a3e40759b1015386
Autor:
Eleonora Porcu, Marco Medici, Giorgio Pistis, Claudia B Volpato, Scott G Wilson, Anne R Cappola, Steffan D Bos, Joris Deelen, Martin den Heijer, Rachel M Freathy, Jari Lahti, Chunyu Liu, Lorna M Lopez, Ilja M Nolte, Jeffrey R O'Connell, Toshiko Tanaka, Stella Trompet, Alice Arnold, Stefania Bandinelli, Marian Beekman, Stefan Böhringer, Suzanne J Brown, Brendan M Buckley, Clara Camaschella, Anton J M de Craen, Gail Davies, Marieke C H de Visser, Ian Ford, Tom Forsen, Timothy M Frayling, Laura Fugazzola, Martin Gögele, Andrew T Hattersley, Ad R Hermus, Albert Hofman, Jeanine J Houwing-Duistermaat, Richard A Jensen, Eero Kajantie, Margreet Kloppenburg, Ee M Lim, Corrado Masciullo, Stefano Mariotti, Cosetta Minelli, Braxton D Mitchell, Ramaiah Nagaraja, Romana T Netea-Maier, Aarno Palotie, Luca Persani, Maria G Piras, Bruce M Psaty, Katri Räikkönen, J Brent Richards, Fernando Rivadeneira, Cinzia Sala, Mona M Sabra, Naveed Sattar, Beverley M Shields, Nicole Soranzo, John M Starr, David J Stott, Fred C G J Sweep, Gianluca Usala, Melanie M van der Klauw, Diana van Heemst, Alies van Mullem, Sita H Vermeulen, W Edward Visser, John P Walsh, Rudi G J Westendorp, Elisabeth Widen, Guangju Zhai, Francesco Cucca, Ian J Deary, Johan G Eriksson, Luigi Ferrucci, Caroline S Fox, J Wouter Jukema, Lambertus A Kiemeney, Peter P Pramstaller, David Schlessinger, Alan R Shuldiner, Eline P Slagboom, André G Uitterlinden, Bijay Vaidya, Theo J Visser, Bruce H R Wolffenbuttel, Ingrid Meulenbelt, Jerome I Rotter, Tim D Spector, Andrew A Hicks, Daniela Toniolo, Serena Sanna, Robin P Peeters, Silvia Naitza
Publikováno v:
PLoS Genetics, Vol 9, Iss 2, p e1003266 (2013)
Thyroid hormone is essential for normal metabolism and development, and overt abnormalities in thyroid function lead to common endocrine disorders affecting approximately 10% of individuals over their life span. In addition, even mild alterations in
Externí odkaz:
https://doaj.org/article/e69c66d7aa444da8a3bac096f4be9764