Zobrazeno 1 - 10
of 45
pro vyhledávání: '"W E Van Nostrand"'
Publikováno v:
Neurodegenerative Diseases. 10:108-111
Background/Aims: There is increased amyloid-β protein precursor (AβPP) expression and amyloid-β protein (Aβ) production in the brain shortly following cerebral ischemic stroke in rodent models. It has been postulated that this may seed amyloid de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb94f9a1599449e4dd8d2086bdfcb7bd
https://doi.org/10.1159/000334763
https://doi.org/10.1159/000334763
Publikováno v:
Neuropathology and Applied Neurobiology. 37:75-93
Cerebral amyloid angiopathy (CAA) may result from focal to widespread amyloid-β protein (Aβ) deposition within leptomeningeal and intracortical cerebral blood vessels. In addition, pericapillary Aβ refers to Aβ depositions in the glia limitans an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef65e10df00aa28266530b0a2f766b27
https://doi.org/10.1111/j.1365-2990.2010.01137.x
https://doi.org/10.1111/j.1365-2990.2010.01137.x
Autor:
A.M. Grande, Feng Xu, M. Vasek, John K. Robinson, Judianne Davis, Mary Lou Previti, W E Van Nostrand
Publikováno v:
Neuroscience. 146:98-107
Cerebral microvascular amyloid β protein (Aβ) deposition and associated neuroinflammation are increasingly recognized as an important component leading to cognitive impairment in Alzheimer’s disease and related cerebral amyloid angiopathy (CAA) d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5799c7e930e630ab40fe54ac4fe4fd91
https://doi.org/10.1016/j.neuroscience.2007.01.043
https://doi.org/10.1016/j.neuroscience.2007.01.043
Publikováno v:
Journal of Neurochemistry. 65:931-934
The progression of Alzheimer's disease and related disorders involves amyloid beta-protein (A beta) deposition and pathologic changes in the parenchyma as well as cerebral blood vessels. The cerebrovascular A beta deposits in these disorders are asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7506349fda00e18a31b38820285b1365
https://doi.org/10.1046/j.1471-4159.1995.65020931.x
https://doi.org/10.1046/j.1471-4159.1995.65020931.x
Autor:
M Porter, W E Van Nostrand
Publikováno v:
Biochemistry. 38:11570-11576
Cerebrovascular amyloid beta-protein (A beta) deposition, a key pathological feature of Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis Dutch-type, can lead to intracerebral hemorrhage; however, the mechanism for this remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6165b76e33d76d14c1f76d8363ecdca6
https://doi.org/10.1021/bi990610f
https://doi.org/10.1021/bi990610f
Publikováno v:
Journal of Biological Chemistry. 270:22827-22830
The Alzheimer's disease related protein, amyloid beta-protein precursor (A beta PP), contains a domain homologous to Kunitz-type serine protease inhibitors (KPI). The recombinant KPI domain of A beta PP is a potent inhibitor of coagulation factors XI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92cb9392e51eea606832b357f7eea83c
https://doi.org/10.1074/jbc.270.39.22827
https://doi.org/10.1074/jbc.270.39.22827
Publikováno v:
Virchows Archiv, 426(6), 603-610. Springer Verlag
In Alzheimer's disease (AD) patients, the complement components Clq, C4 and C3 can be detected in different types of beta/A4 plaques, one of the hallmarks of AD. Contradictory findings on the presence of late complement components in AD brains have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd7919715002d0cb34e6cb88902753f
https://doi.org/10.1007/bf00192116
https://doi.org/10.1007/bf00192116
Publikováno v:
Acta neuropathologica, 89(4), 356-362. Springer Verlag
In the present immunohistochemical study, we investigated the characteristics of altered neurites in the frontal cortex of 10 Alzheimer's disease (AD) brains and 15 age-matched non-demented control brains. In both AD and control cases, the altered ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d40ba71f86ad849a8638cba3926fd8e6
https://doi.org/10.1007/bf00309629
https://doi.org/10.1007/bf00309629
Autor:
Dirk J. Ruiter, R.M.W. de Waal, Pieter Wesseling, W E Van Nostrand, Marcel M. Verbeek, Irene Otte-Höller, C. Sorg
Publikováno v:
Acta Neuropathologica, 90, pp. 493-503
Acta Neuropathologica, 90, 493-503
Acta Neuropathologica, 90, 5, pp. 493-503
Acta Neuropathologica, 90, 493-503
Acta Neuropathologica, 90, 5, pp. 493-503
One of the major histopathological lesions in brains of patients with dementia of the Alzheimer type (DAT) is the senile plaque. Although previous studies have shown that senile plaques are often accompanied by microglial cells, the role of these cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10c9d3002f9644a6eafdf4214fab16c2
https://hdl.handle.net/2066/121105
https://hdl.handle.net/2066/121105
Autor:
Susan M. Saporito-irwin, Dennis D. Cunningham, J Davis-Salinas, W E Van Nostrand, Frances M. Donovan
Publikováno v:
Journal of Biological Chemistry. 269:22623-22627
The amyloid beta-protein (A beta) and protease nexin-2/amyloid beta-protein precursor (PN-2/A beta PP) are major constituents of senile plaques and cerebrovascular deposits in individuals with Alzheimer's disease and related disorders. It has been su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e86602f8f9772ee205bf3bfc20e1569e
https://doi.org/10.1016/s0021-9258(17)31691-5
https://doi.org/10.1016/s0021-9258(17)31691-5