Zobrazeno 1 - 10
of 84
pro vyhledávání: '"W E Mitch"'
Autor:
Harold A. Franch, W E Mitch
Publikováno v:
Nephron Experimental Nephrology. 6:78-83
Therapeutic ribozymes are created through a multistep process that requires trial and error. There are few established rules governing ribozyme design, but guidelines are emerging. It is not yet known whether hammerheads and hairpins, the two ribozym
Autor:
W E Mitch
Publikováno v:
Journal of the American College of Nutrition. 14:311-316
Dietary protein restriction is an established method of preventing the symptoms of uremia but three questions should be asked before beginning this type of therapy: Will the diet maintain adequate nutrition? Can compliance be monitored? Will the low-
Publikováno v:
Journal of the American Society of Nephrology. 5:1066-1073
A woman with mild chronic renal insufficiency was being treated with glucocorticoids for a presumed chronic inflammatory disease. She developed peritonitis arising from a pelvic abscess, which was drained without complications. Unexpectedly, she beca
Autor:
W E, Mitch
Publikováno v:
Journal of nephrology. 19
Acid-base balance is precisely regulated by pulmonary and renal responses while body buffers help to control pH. When its regulation becomes abnormal, accumulation of hydrogen ions cause metabolic acidosis and several responses are activated. These r
Autor:
E, Löfberg, A, Gutierrez, J, Wernerman, B, Anderstam, W E, Mitch, S R, Price, J, Bergström, A, Alvestrand
Publikováno v:
European journal of clinical investigation. 32(5)
Treatment with glucocorticosteroids causes a negative nitrogen balance, but the kinetic mechanisms responsible for this catabolic effect are controversial. We investigated the effects of 60 mg day(-1) prednisolone on protein synthesis and degradation
Autor:
H A, Franch, W E, Mitch
Publikováno v:
Journal of the American Society of Nephrology : JASN. 9
Chronic metabolic acidosis stimulates the catabolism of bone and muscle in experimental animals and humans. The toxicity caused by acidosis involves changes in endocrine function and toxicity arising from the homeostatic responses that are activated
Autor:
R M, Krauss, R H, Eckel, B, Howard, L J, Appel, S R, Daniels, R J, Deckelbaum, J W, Erdman, P, Kris-Etherton, I J, Goldberg, T A, Kotchen, A H, Lichtenstein, W E, Mitch, R, Mullis, K, Robinson, J, Wylie-Rosett, S, St Jeor, J, Suttie, D L, Tribble, T L, Bazzarre
Publikováno v:
The Journal of nutrition. 131(1)
Autor:
J L, Bailey, W E, Mitch
Publikováno v:
Seminars in dialysis. 13(4)
Much has been learned from animal studies in chronic renal failure that is germane to clinical studies because animal models parallel human responses. Such studies have affirmed that correction of metabolic acidosis has a favorable effect on protein
Autor:
J L, Bailey, W E, Mitch
Publikováno v:
Journal of nephrology. 13(2)
Uremia induces substantial changes in protein metabolism. The branched-chain amino acids serve as useful markers of these changes and their catabolism is increased in uremia, particularly in the presence of metabolic acidosis. Glucocorticoids also ar