Zobrazeno 1 - 10
of 20
pro vyhledávání: '"W E Hornbuckle"'
The woodchuck hepatitis virus X gene is important for establishment of virus infection in woodchucks
Autor:
Rob Anderson, P. J. Cote, Rosina Girones, Shuichi Kaneko, W. E. Hornbuckle, Roger H. Miller, Hong-Shu Chen, John L. Gerin, Robert H. Purcell, B. C. Tennant
Publikováno v:
Scopus-Elsevier
All mammalian hepadnaviruses possess a gene, termed X, that encodes a protein capable of transactivating virus gene expression. The X gene overlaps the polymerase and precore genes as well as two newly identified open reading frames (ORFs) termed ORF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3621b979973c172f52119e618875621e
https://doi.org/10.1128/jvi.67.3.1218-1226.1993
https://doi.org/10.1128/jvi.67.3.1218-1226.1993
Autor:
P J Cote, B E Korba, H Steinberg, C Ramirez-Mejia, B Baldwin, W E Hornbuckle, B C Tennant, J L Gerin
Publikováno v:
The Journal of Immunology. 146:3138-3144
Immunosuppression is known to influence the state of chronic hepatitis B virus infection, and is thought to increase the risk of developing chronic infection in newly exposed individuals. Cyclosporin A (CsA), an immunosuppressive agent that inhibits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af43487ea21c334713b1dfbebd5e750b
https://doi.org/10.4049/jimmunol.146.9.3138
https://doi.org/10.4049/jimmunol.146.9.3138
Autor:
Michael C. Kew, P. J. Cote, B. C. Tennant, W. E. Hornbuckle, Roger H. Miller, Hong-Shu Chen, John L. Gerin, Robert H. Purcell
Publikováno v:
Journal of Virology. 66:5682-5684
A number of naturally occurring hepatitis B virus mutants that cannot synthesize the virus precore protein have been identified. Such mutants have been associated with more severe forms of hepatitis, including fulminant hepatitis. The most common mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba1f889f6629dadffefe6ec57a6f9942
https://doi.org/10.1128/jvi.66.9.5682-5684.1992
https://doi.org/10.1128/jvi.66.9.5682-5684.1992
Publikováno v:
Journal of medical virology. 54(2)
In vivo transfection of Eastern woodchucks (Marmota monax) with recombinant woodchuck hepatitis virus (WHV) DNA is effective in inducing virus infection for the study of replication, pathogenicity, and oncogenicity of wild-type and mutated WHV. The o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::704ecae7ddeda27043fb9d7b4041506e
https://pubmed.ncbi.nlm.nih.gov/9496365
https://pubmed.ncbi.nlm.nih.gov/9496365
Autor:
W, Lewis, B, Griniuviene, K O, Tankersley, E S, Levine, R, Montione, L, Engelman, G, de Courten-Myers, M A, Ascenzi, W E, Hornbuckle, J L, Gerin, B C, Tennant
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 76(1)
Fialuridine (FIAU, 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodouracil) is toxic to liver, heart, muscle, and nerve in clinical trials for chronic viral hepatitis (CH). Mitochondrial toxicity was hypothesized. To address pathophysiologic mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8321834f93e78c8e11c20608cdb2fff
https://pubmed.ncbi.nlm.nih.gov/9010451
https://pubmed.ncbi.nlm.nih.gov/9010451
Autor:
John L. Gerin, K. N. Wright, Karl Y. Hostetler, Hong Xie, Bud C. Tennant, Brent A. Korba, W. E. Hornbuckle
Publikováno v:
Hepatology (Baltimore, Md.). 23(5)
It would be desirable to develop antiviral agents that can be targeted to liver to enhance their antiviral effects and reduce nonhepatic toxicity. 2',3'-Dideoxyguanosine (ddG) has been found to be a potent and selective antihepatitis B agent both in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13587a5c98af7d5bab98e06d7fc8b120
https://pubmed.ncbi.nlm.nih.gov/8621175
https://pubmed.ncbi.nlm.nih.gov/8621175
Publikováno v:
Journal of the American Veterinary Medical Association. 205(12)
Cryptosporidium oocysts were found in the feces of a 6-month-old female cat with persistent diarrhea. The oocysts disappeared from the feces immediately after treatment with paromomycin (165 mg/kg of body weight, PO, for 5 days), and the diarrhea eve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::03fa5353b0ab7be811f378beb29705a1
https://pubmed.ncbi.nlm.nih.gov/7744647
https://pubmed.ncbi.nlm.nih.gov/7744647
Publikováno v:
Hepatology (Baltimore, Md.). 20(1 Pt 1)
We analyzed the DNA ploidy and the nuclear size of hepatocytes within hepatocellular carcinoma, putative preneoplastic (clear cell and basophilic foci) and adjacent non-neoplastic liver in 30 woodchucks neonatally infected with the woodchuck hepatiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::152e0ca488a031cfebdac653cad425aa
https://pubmed.ncbi.nlm.nih.gov/8020890
https://pubmed.ncbi.nlm.nih.gov/8020890
Publikováno v:
American journal of veterinary research. 52(1)
Praziquantel was used successfully for treatment of a small number of dogs and 1 cat infected with Paragonimus kellicotti. To further evaluate the usefulness of this drug in treating such infections, 7 cats and 7 dogs were inoculated orally with meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a63c522b1a5000e8be056d2fb58ea72
https://pubmed.ncbi.nlm.nih.gov/1826991
https://pubmed.ncbi.nlm.nih.gov/1826991
Publikováno v:
Laboratory animal science. 40(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7fe9bc352d7f0779cba2c85c8abc8891
https://pubmed.ncbi.nlm.nih.gov/2153871
https://pubmed.ncbi.nlm.nih.gov/2153871