Zobrazeno 1 - 10
of 17
pro vyhledávání: '"W E, Horton"'
Publikováno v:
Journal of musculoskeletalneuronal interactions. 6(4)
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 103(22)
Among mammals, modern cetaceans (whales, dolphins, and porpoises) are unusual in the absence of hind limbs. However, cetacean embryos do initiate hind-limb bud development. In dolphins, the bud arrests and degenerates around the fifth gestational wee
Publikováno v:
Clinical and experimental rheumatology. 23(1)
A major area under study in the osteoarthritis (OA) research field is the characterization of specific molecular and biochemical changes that distinguish advanced diseased cartilage from less involved or normal tissue. This information is important t
Publikováno v:
Arthritis and rheumatism. 43(7)
To test the hypothesis that magnetic resonance imaging (MRI) results correlate with the biochemical composition of cartilage matrix and can therefore be used to evaluate natural tissue development and the effects of biologic interventions.Chondrocyte
Autor:
C S, Adams, W E, Horton
Publikováno v:
The Anatomical record. 250(4)
Apoptosis in vivo has been identified in developing cartilage from embryonic chick sterna and avian and murine growth plates. To date, no evidence exists that chondrocytes in articular cartilage undergo apoptosis.We examined the distribution of cells
Publikováno v:
Journal of neuroscience research. 47(3)
The cause of neuronal loss in Alzheimer disease is unknown. We investigated the effects on survival of PC12 cells expressing A692G, E693Q, and V717F mutant amyloid precursor proteins (APP). Differentiated cells expressing mutant APPs exhibited somal
Autor:
W E, Horton, S F, Tillman
Publikováno v:
Musclenerve. Supplement. 5
Publikováno v:
Laboratory animal science. 45(2)
We have carried out a comparison of cartilage degeneration that develops spontaneously with age in the Wistar and Fischer 344 rats. Young adult (6-month-old) Wistar rats were essentially free of any relevant lesion in the articular cartilage of the k
Publikováno v:
The Journal of biological chemistry. 266(36)
We have examined the effects of various analogs of vitamin D on the expression of the aggrecan proteoglycan by an immortalized rat chondrocyte cell line. The active metabolite of vitamin D, 1,25-dihydroxyvitamin D3 (1,25(OH)2D3), produced a concentra
Publikováno v:
The Journal of biological chemistry. 266(30)
Collagen II is synthesized at high levels by differentiated chondrocytes. A 620-base pair DNA sequence in the first intron of the rat collagen II gene was previously determined to have chondrocyte-specific enhancer activity. Using mobility shift assa