Výsledky vyhledávání - "W E, Achanzar"

Cadmium-induced malignant transformation of human prostate epithelial cells

Autor: W E, Achanzar, B A, Diwan, J, Liu, S T, Quader, M M, Webber, M P, Waalkes

Publikováno v: Cancer research. 61(2)

Prostate cancer has become epidemic, and environmental factors such as cadmium may be partly responsible. This study reports malignant transformation of the nontumorigenic human prostatic epithelial cell line RWPE-1 by in vitro cadmium exposure. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6e9ef3ed6ebefc77dbb9d9cac26c1ac2
https://pubmed.ncbi.nlm.nih.gov/11212230

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Spontaneous transformation of cultured rat liver (TRL 1215) cells is associated with down-regulation of metallothionein: implications for sensitivity to cadmium cytotoxicity and genotoxicity

Autor: T P, Coogan, W E, Achanzar, M P, Waalkes

Publikováno v: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 19(3)

Previously, we found cadmium (Cd) to be effective in suppressing liver and lung tumors in rodents. Thus, this study investigated the susceptibility of cultured cells to Cd during spontaneous transformation. The TRL 1215 cell line is an epithelial-lik

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6db22210556225d2b95e6f027ba97acd
https://pubmed.ncbi.nlm.nih.gov/10983892

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