Zobrazeno 1 - 10
of 402
pro vyhledávání: '"W David, Wilson"'
Autor:
J. Ross Terrell, Thao T. Le, Ananya Paul, Margo A. Brinton, W. David Wilson, Gregory M. K. Poon, Markus W. Germann, Jessica L. Siemer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Potential G-quadruplex sites have been identified in the genomes of DNA and RNA viruses and proposed as regulatory elements. The genus Orthoflavivirus contains arthropod-transmitted, positive-sense, single-stranded RNA viruses that cause sig
Externí odkaz:
https://doaj.org/article/8e9f01cae3524f5faf463f7f903561c0
Autor:
J. Ross Terrell, Samuel J. Taylor, Amelia L. Schneider, Yue Lu, Tyler N. Vernon, Suela Xhani, Ryan H. Gumpper, Ming Luo, W. David Wilson, Ulrich Steidl, Gregory M.K. Poon
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112671- (2023)
Summary: The master transcriptional regulator PU.1/Spi-1 engages DNA sites with affinities spanning multiple orders of magnitude. To elucidate this remarkable plasticity, we have characterized 22 high-resolution co-crystallographic PU.1/DNA complexes
Externí odkaz:
https://doaj.org/article/3a08b530979c4b649e48bbf830396248
Autor:
Mathijs J. P. Theelen, W. David Wilson, Barbara A. Byrne, Judy M. Edman, Philip H. Kass, Lapo Mughini‐Gras, K. Gary Magdesian
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 34, Iss 2, Pp 955-963 (2020)
Abstract Background Antimicrobial treatment protocols for foals with sepsis that do not improve clinically often are adjusted based on bacteriological and antimicrobial susceptibility testing results from samples collected at hospital admission. Obje
Externí odkaz:
https://doaj.org/article/dec70cb4406f4cb3b8f5598ccb873531
Publikováno v:
Life, Vol 12, Iss 5, p 681 (2022)
Ken Breslauer began studies on the thermodynamics of small cationic molecules binding in the DNA minor groove over 30 years ago, and the studies reported here are an extension of those ground-breaking reports. The goals of this report are to develop
Externí odkaz:
https://doaj.org/article/195dc44dee6040369a654f4f3bdfe658
Autor:
Roberto Simone, Rubika Balendra, Thomas G Moens, Elisavet Preza, Katherine M Wilson, Amanda Heslegrave, Nathan S Woodling, Teresa Niccoli, Javier Gilbert‐Jaramillo, Samir Abdelkarim, Emma L Clayton, Mica Clarke, Marie‐Therese Konrad, Andrew J Nicoll, Jamie S Mitchell, Andrea Calvo, Adriano Chio, Henry Houlden, James M Polke, Mohamed A Ismail, Chad E Stephens, Tam Vo, Abdelbasset A Farahat, W David Wilson, David W Boykin, Henrik Zetterberg, Linda Partridge, Selina Wray, Gary Parkinson, Stephen Neidle, Rickie Patani, Pietro Fratta, Adrian M Isaacs
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 1, Pp 22-31 (2017)
Abstract Intronic GGGGCC repeat expansions in C9orf72 are the most common known cause of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), which are characterised by degeneration of cortical and motor neurons, respectively. Repea
Externí odkaz:
https://doaj.org/article/1f8b61ee6cea4757929c90eeb5c2d015
Autor:
Edwin N. Ogbonna, Ananya Paul, Abdelbasset A. Farahat, J. Ross Terrell, Ekaterina Mineva, Victor Ogbonna, David W Boykin, W. David Wilson
Publikováno v:
ACS Bio & Med Chem Au.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bce4459c3795d2e10328487b14578309
https://doi.org/10.1021/acsbiomedchemau.3c00002
https://doi.org/10.1021/acsbiomedchemau.3c00002
Publikováno v:
Current Protocols. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b037f85516616408dc5c6b3090f3d3b
https://doi.org/10.1002/cpz1.729
https://doi.org/10.1002/cpz1.729
Autor:
Abdelbasset A. Farahat, Arvind Kumar, Tanja Wenzler, Reto Brun, Ananya Paul, Pu Guo, W. David Wilson, David W. Boykin
New analogs of the antiprotozoal agent Furamidine were prepared utilizing Stille coupling reactions and amidation of the bisnitrile intermediate using lithium bis-trimethylsilylamide. Both the phenyl groups and the furan moiety of furamidine were rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e49411482d3e0a0f86edc530532fd2a
Autor:
Sarah Laughlin, W. David Wilson
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 10, Pp 24506-24531 (2015)
Electrospray ionization mass spectrometry has become invaluable in the characterization of macromolecular biological systems such as nucleic acids and proteins. Recent advances in the field of mass spectrometry and the soft conditions characteristic
Externí odkaz:
https://doaj.org/article/95120788e788415fb0f2e5a034e8fbb3
Autor:
W. David Wilson, Ananya Paul
Publikováno v:
Nucleic Acids in Chemistry and Biology ISBN: 9781788019040
Historically, small molecules have targeted double helical DNA through intercalation and minor groove complexes. Initially, small molecules to target RNA were focused on RNAs involved in protein biosynthesis. Now, many more compounds to target divers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::916335475f5d8c5959777c877ac3fa2d
https://doi.org/10.1039/9781837671328-00477
https://doi.org/10.1039/9781837671328-00477