Zobrazeno 1 - 10
of 31
pro vyhledávání: '"W D Jarvis"'
Publikováno v:
Leukemia. 17:2140-2148
The present studies examined performance of SAPK cascades and apoptotic commitment following ribosomal trauma in REH lymphoid leukemia cells. Ribostatic insults included disruption of ribosomal activity by mechanistically dissimilar agents such as bl
Autor:
Paul B. Fisher, R H Decker, Zhiliang Wang, C R Johnson, M Ehinger, Victoria M. Richon, Steven Grant, J. A. Vrana, W D Jarvis
Publikováno v:
Oncogene. 18:7016-7025
Determinants of differentiation and apoptosis in myelomonocytic leukemia cells (U937) exposed to the novel hybrid polar compound SAHA (suberoylanilide hydroxamic acid) have been examined. In contrast to hexamethylenbisacetamide (HMBA), SAHA-related m
Autor:
Barbour Se, Auer Kl, Michael J. Birrer, S. Grant, Eva Szabo, Freemerman Aj, C. R. Johnson, F. A. Fornari, W. D. Jarvis, P. Dent
Publikováno v:
Molecular Pharmacology. 52:935-947
SUMMARY We characterized participation of the stress-activated protein kinase (SAPK) cascade in the lethal actions of the cytotoxic lipid messengers ceramide and sphingosine in U937 human monoblastic leukemia cells. Acute exposure of U937 cells to ei
Autor:
Mark S. Spector, Edward J. N. Ishac, Bin Gao, George Kunos, W. D. Jarvis, Kelly L. Auer, Paul Dent
Publikováno v:
Molecular and Cellular Biology. 17:3556-3565
To study the mechanisms by which catecholamines regulate hepatocyte proliferation after partial hepatectomy (PHX), hepatocytes were isolated from adult male rats 24 h after sham operation or two-thirds PHX and treated with catecholamines and other ag
Autor:
W. D. Jarvis, Phillip B. Hylemon, Emily C. Gurley, Z R Vlahcevic, Y P Rao, Richard T. Stravitz
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 271:G293-G303
We have recently shown that taurocholate (TCA) represses the transcriptional activity of cholesterol 7 alpha-hydroxylase, the rate-limiting enzyme of the bile acid biosynthetic pathway, through a protein kinase C (PKC)-dependent mechanism in primary
Autor:
Robert Bittman, Steven Grant, W D Jarvis, Rebecca Traylor, Ravi Kumar Erukulla, L. B. Kramer, H. A. Martin, Frank A. Fornari
Publikováno v:
Journal of Biological Chemistry. 271:8275-8284
Prior studies demonstrated that ceramide promotes apoptotic cell death in the human myeloid leukemia cell lines HL-60 and U937 (Jarvis, W. D., Kolesnick, R. N., Fornari, F. A., Jr., Traylor, R. S., Gewirtz, D. A., and Grant, S. (1994) Proc. Natl. Aca
Publikováno v:
International Journal of Radiation Biology. 69:183-192
Ionizing radiation produced a dose-dependent reduction in the proliferative capacity of HL-60 human promyelocytic leukaemia cells. A small percentage of the cell population demonstrated morphological evidence of apoptosis at 24h following radiation d
Publikováno v:
Journal of Biological Chemistry. 269:31685-31692
Prior studies demonstrated that increased intracellular availability of ceramide induces apoptotic DNA degradation and cell death in the human leukemia cell lines HL-60 and U937 (Jarvis, W. D., Kolesnick, R. N., Fornari, F. A., Traylor, R. S., Gewirt
Publikováno v:
Proceedings of the National Academy of Sciences. 91:73-77
The potential involvement of ceramide-related signaling processes in the induction of apoptosis by tumor necrosis factor alpha was assessed by multiple biochemical strategies in the human leukemic cell lines HL-60 and U937 and the murine fibrosarcoma
Publikováno v:
British Journal of Haematology. 82:522-528
The effects of the protein kinase C activator bryostatin 1, either with or without recombinant granulocyte-macrophage colony stimulating factor (rGM-CSF) were examined with respect to the in vitro metabolism of ara-C in leukaemic myeloblasts obtained