Zobrazeno 1 - 10
of 11
pro vyhledávání: '"W D, Tilley"'
Publikováno v:
Cancer metastasis reviews. 20(3-4)
Although prostate cancer is heterogeneous in its etiology and progression, androgen signaling through the androgen receptor (AR) appears to be involved in all aspects of the disease, from initiation to development of treatment resistance. Lifetime ex
Publikováno v:
Cancer research. 61(3)
We have previously demonstrated that peritumoral stromal matrix derived from prostate cancer patients who relapse after radical surgery contains elevated levels of versican. The purpose of this study was to determine whether prostate cancer cells con
Publikováno v:
Journal of mammary gland biology and neoplasia. 3(1)
Although the androgen receptor (AR)3 is often co-expressed with the estrogen receptor (ER) and progesterone receptor (PR) in human breast tumors, its role in breast cancer is poorly understood. Specific growth stimulatory and inhibitory actions of an
Autor:
J A, Clements, P, Rohde, V, Allen, V J, Hyland, M L, Samaratunga, W D, Tilley, M F, Lavin, R A, Gardiner
Publikováno v:
The Journal of urology. 161(4)
To determine whether prostatic cells were normally present in ejaculate and if the sensitivity and specificity of the detection of malignant prostate cells in ejaculate and urethral washings from men with suspected prostate cancer could be improved u
Autor:
C, Ricciardelli, K, Mayne, P J, Sykes, W A, Raymond, K, McCaul, V R, Marshall, W D, Tilley, J M, Skinner, D J, Horsfall
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 3(6)
Curative therapies for clinically localized prostate cancer have significant morbidity, and those patients who might be cured by aggressive management are not easily identified using current clinical information. Better biomarkers of tumor behavior n
Publikováno v:
The Journal of urology. 157(6)
Vascular endothelial growth factor (VEGF) is a potent inducer of endothelial cell growth and is expressed at elevated levels in several tumor types. In this study immunohistochemical localization and distribution of isoforms of VEGF were examined in
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 2(2)
Progression to androgen-independent growth of human prostate cancers may be mediated by alterations in the structure and/or expression of the androgen receptor (AR) gene. To date, mutations in the AR gene have largely been identified in hormone refra
Publikováno v:
Cancer research. 54(15)
To determine whether multiple features of immunohistochemical staining of the androgen receptor (AR) in prostate cancer could reliably predict androgen dependence, tumor biopsy specimens from 30 patients (stages A-D2) were stained using anti-peptide
Autor:
D J, Horsfall, K, Mayne, C, Ricciardelli, M, Rao, J M, Skinner, D W, Henderson, V R, Marshall, W D, Tilley
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 70(5)
The histology of benign disease of the human prostate (benign prostatic hyperplasia) is heterogeneous. No other species demonstrates the same complexity, and current animal models do not appear to fully encompass the stromal and epithelial developmen
Publikováno v:
Cancer research. 50(17)
Responses to androgen vary widely among prostate cancers and prostatic carcinoma cell lines. We have explored the basis for this heterogeneity by examining the levels of androgen receptor expression in a prostate carcinoma cell line (LNCaP) that expr