Zobrazeno 1 - 4
of 4
pro vyhledávání: '"W D, Medina"'
Publikováno v:
The Journal of the Kentucky Medical Association. 83(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9035a92b5c6ea5bd3991111851d2e5a9
https://pubmed.ncbi.nlm.nih.gov/4078485
https://pubmed.ncbi.nlm.nih.gov/4078485
Autor:
J R, Bertino, M D, Carman, H L, Weiner, A, Cashmore, B A, Moroson, S, Srimatkandada, J H, Schornagel, W D, Medina, S K, Dube
Publikováno v:
Cancer treatment reports. 67(10)
Two known mechanisms by which neoplastic cells may become resistant to chemotherapeutic agents are reviewed, using methotrexate (MTX) resistance as a model. These mechanisms are an increased level of target enzyme, found in several instances to be a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db57750d8bcdfdee737bd368011845d9
https://pubmed.ncbi.nlm.nih.gov/6354438
https://pubmed.ncbi.nlm.nih.gov/6354438
Publikováno v:
Blood. 62(1)
Genetic transformation of murine bone marrow stem cells to methotrexate resistance was achieved using a modified calcium phosphate-DNA coprecipitation procedure. Bone marrow cells were transformed by DNA derived from methotrexate-resistant mouse 3T6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::553a3d3d0e9f263b72a0cf578868dbc0
https://pubmed.ncbi.nlm.nih.gov/6574796
https://pubmed.ncbi.nlm.nih.gov/6574796
Publikováno v:
Cancer research. 45(1)
A methotrexate-resistant subline, CCRF-CEM/R1, was selected stepwise from the human leukemic lymphoblast T-cell line, CCRF-CEM, and maintained in 0.2 microM methotrexate. The development of resistance to methotrexate (75-fold) was associated with a 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2fcf9469d078564a887c0d686d00e526
https://pubmed.ncbi.nlm.nih.gov/3855283
https://pubmed.ncbi.nlm.nih.gov/3855283