Zobrazeno 1 - 10
of 586
pro vyhledávání: '"W D'Souza"'
Autor:
Dong‐Rui Chen, Ke Cheng, Lei Wan, Chao‐Yue Cui, Gong Li, Dong‐Hao Zhao, Yang Yu, Xiao‐Ping Liao, Ya‐Hong Liu, Alaric W. D'Souza, Xin‐Lei Lian, Jian Sun
Publikováno v:
iMeta, Vol 3, Iss 1, Pp n/a-n/a (2024)
Abstract Antimicrobial resistance (AMR) is a major threat to global public health, and antibiotic resistance genes (ARGs) are widely distributed across humans, animals, and environment. Farming environments are emerging as a key research area for ARG
Externí odkaz:
https://doaj.org/article/a722f4857fcf47178163b6fc51c43660
Autor:
Kazumasa Manabe, Andrew W. D’Souza, Takuro Washio, Ryosuke Takeda, Sarah L. Hissen, John D. Akins, Qi Fu
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Excessive sympathetic activity during exercise causes heightened peripheral vasoconstriction, which can reduce oxygen delivery to active muscles, resulting in exercise intolerance. Although both patients suffering from heart failure with preserved an
Externí odkaz:
https://doaj.org/article/7372f18ce087499bbb83e31123f4b4da
Autor:
Peter J. Stogios, Emily Bordeleau, Zhiyu Xu, Tatiana Skarina, Elena Evdokimova, Sommer Chou, Luke Diorio-Toth, Alaric W. D’Souza, Sanket Patel, Gautam Dantas, Gerard D. Wright, Alexei Savchenko
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
A comprehensive functional and structural study of the Antibiotic_NAT family of aminoglycoside acetyltransferases provides new insight into the molecular mechanisms underlying resistance to existing and emerging aminoglycoside antibiotics.
Externí odkaz:
https://doaj.org/article/060d49707a29418ba99fc5221b511acc
Autor:
Alaric W. D’Souza, Manish Boolchandani, Sanket Patel, Gianluca Galazzo, Jarne M. van Hattem, Maris S. Arcilla, Damian C. Melles, Menno D. de Jong, Constance Schultsz, COMBAT Consortium, Gautam Dantas, John Penders
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-21 (2021)
Abstract Background Antimicrobial-resistant bacteria and their antimicrobial resistance (AMR) genes can spread by hitchhiking in human guts. International travel can exacerbate this public health threat when travelers acquire AMR genes endemic to the
Externí odkaz:
https://doaj.org/article/1320836afcd4449184bf3388301f7b16
Autor:
Stephen W. D’Souza, Jocelyn D. Glazier
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Homocysteine is a metabolite generated by methionine cycle metabolism, comprising the demethylated derivative of methionine. Homocysteine can be metabolised by the transsulphuration pathway to cystathionine, which requires vitamin B6, or can undergo
Externí odkaz:
https://doaj.org/article/d0dbb80993764f93ba7b362ec8dd6912
Autor:
Jian Sun, Xiao-Ping Liao, Alaric W. D’Souza, Manish Boolchandani, Sheng-Hui Li, Ke Cheng, José Luis Martínez, Liang Li, You-Jun Feng, Liang-Xing Fang, Ting Huang, Jing Xia, Yang Yu, Yu-Feng Zhou, Yong-Xue Sun, Xian-Bo Deng, Zhen-Ling Zeng, Hong-Xia Jiang, Bing-Hu Fang, You-Zhi Tang, Xin-Lei Lian, Rong-Min Zhang, Zhi-Wei Fang, Qiu-Long Yan, Gautam Dantas, Ya-Hong Liu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Environments where antibiotics are used indiscriminately exhibit microbial communities that can represent hot-spots of resistance gene enrichment, which in turn could spread to humans. Here, the authors characterize how exposure to swine farms enviro
Externí odkaz:
https://doaj.org/article/f43a980b278f48d79417afb240dde2c7
Autor:
Edwin W D'Souza, Andrew J MacGregor, Amber L Dougherty, Andrew S Olson, Howard R Champion, Michael R Galarneau
Publikováno v:
PLoS ONE, Vol 17, Iss 4, p e0266588 (2022)
BackgroundThe U.S. military conflicts in Iraq and Afghanistan had the most casualties since Vietnam with more than 53,000 wounded in action. Novel injury mechanisms, such as improvised explosive devices, and higher rates of survivability compared wit
Externí odkaz:
https://doaj.org/article/f0575426f8e848c5a886f19f1ca9086f
Autor:
Kimberley V. Sukhum, Rhiannon C. Vargas, Manish Boolchandani, Alaric W. D’Souza, Sanket Patel, Akhil Kesaraju, Gretchen Walljasper, Harshad Hegde, Zhan Ye, Robert K. Valenzuela, Paul Gunderson, Casper Bendixsen, Gautam Dantas, Sanjay K. Shukla
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
The addition of dairy cow manure—stored in manure pits—to field soil has the potential to introduce not only organic nutrients but also mammalian microbial communities and antimicrobial resistance genes (ARGs) to soil communities. Using shotgun s
Externí odkaz:
https://doaj.org/article/e3434897ff2d43b1a06c864fcfe0ff69
Autor:
Alaric W. D’Souza, Robert F. Potter, Meghan Wallace, Angela Shupe, Sanket Patel, Xiaoqing Sun, Danish Gul, Jennie H. Kwon, Saadia Andleeb, Carey-Ann D. Burnham, Gautam Dantas
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
The authors investigate the burden and spatiotemporal dynamics of multidrug-resistant bacteria on intensive care unit surfaces from two hospitals in the US and Pakistan over a year. They find Acinetobacter baumannii and Enterococcus faecium co-associ
Externí odkaz:
https://doaj.org/article/c0db547ce2594ce6956c69698b2802f6
Autor:
Takuro Washio, Sarah L. Hissen, Ryosuke Takeda, Kazumasa Manabe, John D. Akins, Belinda Sanchez, Andrew W. D’Souza, David B. Nelson, Safia Khan, Andrew R. Tomlinson, Tony G. Babb, Qi Fu
Publikováno v:
Clinical Autonomic Research. 33:121-131