A comprehensive research agenda for zero leprosy

Autor: Peter Steinmann, Courtenay Dusenbury, David Addiss, Fareed Mirza, W. Cairns S. Smith

Publikováno v: Infectious Diseases of Poverty, Vol 9, Iss 1, Pp 1-7 (2020)

Abstract Background Leprosy control achieved dramatic success in the 1980s–1990s with the implementation of short course multidrug therapy, which reduced the global prevalence of leprosy to less than 1 in 10 000 population. However, a period of rel

Externí odkaz: https://doaj.org/article/4df46177b61e43e79c3fe5922b083d50

Leprosy post-exposure prophylaxis with single-dose rifampicin (LPEP): an international feasibility programme

Autor: Jan Hendrik Richardus, ProfPhD, Anuj Tiwari, PhD, Tanja Barth-Jaeggi, PhD, Mohammad A Arif, MD, Nand Lal Banstola, MBA, Rabindra Baskota, MD, David Blaney, MD, David J Blok, PhD, Marc Bonenberger, PhD, Teky Budiawan, MD, Arielle Cavaliero, MPH, Zaahira Gani, MSc, Helena Greter, PhD, Eliane Ignotti, ProfPhD, Deusdedit V Kamara, MD, Christa Kasang, PhD, Pratap R Manglani, MD, Liesbeth Mieras, MD, Blasdus F Njako, MD, Tiara Pakasi, MA, Basu Dev Pandey, PhD, Paul Saunderson, PhD, Rajbir Singh, MD, W Cairns S Smith, ProfPhD, René Stäheli, MSc, Nayani D Suriyarachchi, MD, Aye Tin Maung, MD, Tin Shwe, MD, Jan van Berkel, MA, Wim H van Brakel, PhD, Bart Vander Plaetse, MD, Marcos Virmond, ProfPhD, Millawage S D Wijesinghe, MD, Ann Aerts, MD, Peter Steinmann, PhD

Publikováno v: The Lancet Global Health, Vol 9, Iss 1, Pp e81-e90 (2021)

Summary: Background: Innovative approaches are required for leprosy control to reduce cases and curb transmission of Mycobacterium leprae. Early case detection, contact screening, and chemoprophylaxis are the most promising tools. We aimed to generat

Externí odkaz: https://doaj.org/article/c85388dc97ed4ea2b1c56421e7940d48

The long-term impact of the leprosy post-exposure prophylaxis (Lpep) program on leprosy incidence: a modelling study

Autor: Christa Kasang, David D. Blaney, Mohammad Arif, David J. Blok, Tin Shwe, Pratap R. Manglani, Marc Bonenberger, Jan van Berkel, Marcos Virmond, Wim H. van Brakel, Zaahira Gani, Tiara Pakasi, Paul Saunderson, Millawage Supun Dilara Wijesinghe, Deusdedit V. Kamara, Anuj Tiwari, Aye Tin Maung, Helena Greter, Tanja Barth-Jaeggi, Teky Budiawan, Nand Lal Banstola, Bart Vander Plaetse, Liesbeth Mieras, Rabindra Baskota, Eliane Ignotti, Arielle Cavaliero, Nayani D. Suriyarachchi, Ann Aerts, Blasdus Njako, W. Cairns S. Smith, René Stäheli, Unnati Rani Saha, Jan Hendrik Richardus, Peter Steinmann

Publikováno v: PLoS Neglected Tropical Diseases, 15(3):e0009279. Public Library of Science
PLoS Neglected Tropical Diseases, Vol 15, Iss 3, p e0009279 (2021)
PLoS Neglected Tropical Diseases

Background The Leprosy Post-Exposure Prophylaxis (LPEP) program explored the feasibility and impact of contact tracing and the provision of single dose rifampicin (SDR) to eligible contacts of newly diagnosed leprosy patients in Brazil, India, Indone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9988195604d4cc6dbc221a81fcef0819
https://pure.eur.nl/en/publications/c3745bda-afd2-4abc-bb5c-58076c8303b0

Comparing the clinical and histological diagnosis of leprosy and leprosy reactions in the INFIR cohort of Indian patients with multibacillary leprosy.

Autor: Diana N J Lockwood, Peter Nicholls, W Cairns S Smith, Loretta Das, Pramila Barkataki, Wim van Brakel, Sujai Suneetha

Publikováno v: PLoS Neglected Tropical Diseases, Vol 6, Iss 6, p e1702 (2012)

BACKGROUND: The ILEP Nerve Function Impairment in Reaction (INFIR) is a cohort study designed to identify predictors of reactions and nerve function impairment in leprosy. The aim was to study correlations between clinical and histological diagnosis

Externí odkaz: https://doaj.org/article/60ddf0ce34664317be5d322e2b4e14da

Cost-effectiveness of interventions to prevent disability in leprosy: a systematic review.

Autor: Natasja H J van Veen, Paul McNamee, Jan Hendrik Richardus, W Cairns S Smith

Publikováno v: PLoS ONE, Vol 4, Iss 2, p e4548 (2009)

BackgroundPrevention of disability (POD) is one of the key objectives of leprosy programmes. Recently, coverage and access have been identified as the priority issues in POD. Assessing the cost-effectiveness of POD interventions is highly relevant to

Externí odkaz: https://doaj.org/article/a09e81b0e0544a8fb98bd93709c9c12a