Výsledky vyhledávání - "W C van Schooten"

Purified HLA class II peptide complexes can induce adherence and activation of peptide-specific human T cell clones

Autor: W C van Schooten, T Maiore, K R Jones, L Paborsky

Publikováno v: The Journal of Immunology. 148:1043-1048

An initial event in T cell activation is the specific adherence of T cells via their T cell receptor to the MHC peptide complex. We have studied this adherence by incubating T cells with preformed HLA DR4Dw4 peptide complexes attached to a solid supp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6eaf2723621c7bbe924f73e2a4883ee4
https://doi.org/10.4049/jimmunol.148.4.1043

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Molecular mapping of interactions between a Mycobacterium leprae-specific T cell epitope, the restricting HLA-DR2 molecule, and two specific T cell receptors

Autor: D C Anderson, W C van Schooten, A Janson, M E Barry, R R de Vries

Publikováno v: The Journal of Immunology. 144:2459-2464

A systematic series of 89 single residue substitution analogs of the Mycobacterium leprae 65-kDa protein-derived peptide LQAAPALDKL were tested for stimulation of two HLA-DR2 restricted 65 kDa-reactive T cell clones from a tuberculoid leprosy patient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dbb197be461ea5505bd7b4f669b950ea
https://doi.org/10.4049/jimmunol.144.7.2459

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In vivo persistence of donor cells following adoptive transfer of allogeneic dendritic cells in HIV-infected patients

Autor: M H, Shapero, S K, Kundu, E, Engleman, R, Laus, W C, van Schooten, T C, Merigan

Publikováno v: Cell transplantation. 9(3)

Peripheral blood samples from HIV-seropositive individuals enrolled in a pilot clinical trial investigating the use of allogeneic dendritic cell therapy were evaluated for mixed chimerism. In this study, dendritic cells from HLA-identical, HIV-serone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::759e4fabe9f9cc9dd42308995bc4dc9a
https://pubmed.ncbi.nlm.nih.gov/10972330

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Induction of prostate tumor-specific CD8+ cytotoxic T-lymphocytes in vitro using antigen-presenting cells pulsed with prostatic acid phosphatase peptide

Autor: M V, Peshwa, J D, Shi, C, Ruegg, R, Laus, W C, van Schooten

Publikováno v: The Prostate. 36(2)

Most strategies in cancer immunotherapy are aimed at the induction of a strong cellular immune response against the tumor. Particularly, CD8+ T lymphocytes have been proven in multiple animal models to be critical for the eradication of solid tumors.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::43eec864bae588c2b8b75d94109ff7b8
https://pubmed.ncbi.nlm.nih.gov/9655265

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Generation and ex vivo expansion of HTLV-1 specific CD8+ cytotoxic T-lymphocytes for adoptive immunotherapy

Autor: M V, Peshwa, L A, Page, L, Qian, D, Yang, W C, van Schooten

Publikováno v: Biotechnology and bioengineering. 50(5)

CD8(+) cytotoxic T-lymphocytes (CTLs) have been proven, in multiple animal models, to be the most powerful antiviral and antitumor components of the immune system. We have developed a protocol to activate and expand tumor and virus peptide-specific C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::83f41cc94ed2e71b01c3b4e1781e6db3
https://pubmed.ncbi.nlm.nih.gov/18627015

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Purified HLA class II peptide complexes can induce adherence and activation of peptide-specific human T cell clones

Autor: W C, van Schooten, T, Maiore, K R, Jones, L, Paborsky

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 148(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::205455aeedb18cde6a173ac486e9fb38
https://pubmed.ncbi.nlm.nih.gov/1531349

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Molecular mapping of interactions between a Mycobacterium leprae-specific T cell epitope, the restricting HLA-DR2 molecule, and two specific T cell receptors

Autor: D C, Anderson, W C, van Schooten, A, Janson, M E, Barry, R R, de Vries

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 144(7)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::68c1786f4f90b375067e6f6b5c739647
https://pubmed.ncbi.nlm.nih.gov/1690768

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T cell epitopes on the 36K and 65K Mycobacterium leprae antigens defined by human T cell clones

Autor: W C van Schooten, R. R. P. De Vries, Paul R. Klatser, T H Ottenhoff, J. E. R. Thole, A. H. J. Kolk

Publikováno v: European Journal of Immunology. 18:849-854

To identify the molecular localization and specificity of Mycobacterium leprae antigenic determinants inducing T cell activation, we studied the reactivity of M. leprae-reactive T cell clones from two tuberculoid leprosy patients towards a battery of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1504b3c399fbd509c9f5725d220cc616
https://doi.org/10.1002/eji.1830180604

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A peptidoglycan protein complex purified from M. leprae cell walls contains most or all immunodominant M. leprae T-cell antigens

Autor: T, Mutis, W C, van Schooten, R R, de Vries

Publikováno v: International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association. 57(4)

The outcome of an infection with Mycobacterium leprae is correlated with the T-cell-mediated immune response developed against this pathogenic agent. The identification of M. leprae antigens that are recognized by T cells is therefore of great import

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::29208bde9c8694d35d0362fad654bc11
https://pubmed.ncbi.nlm.nih.gov/2681461

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