Zobrazeno 1 - 10
of 17
pro vyhledávání: '"W C Olson"'
Publikováno v:
Hybridoma. 14:51-57
A monoclonal antibody, EIV-E12, was produced against ellipsoid-associated cells. In postnatal chicks, the antigen defined by EIV-E12 associated with about 90% of bursal cells and accumulated in B cell-rich areas of lymphoid organs. The antigen was ex
Autor:
M L Alegre, A M Collins, V L Pulito, R A Brosius, W C Olson, R A Zivin, R Knowles, J R Thistlethwaite, L K Jolliffe, J A Bluestone
Publikováno v:
The Journal of Immunology. 148:3461-3468
The binding specificity of the murine OKT3 has been transferred into a human antibody framework to reduce its immunogenicity. This "humanized" anti-CD3 mAb (gOKT3-5) was previously shown to retain, in vitro, all the properties of native OKT3, includi
Publikováno v:
Journal of Virology. 64:6054-6062
Infection of 1-day-old chicks with reticuloendotheliosis virus strain T induces a neoplastic disease that kills the chicks 7 to 14 days postinfection. In association with reticuloendotheliosis-associated virus (REV-A), reticuloendotheliosis virus T (
Publikováno v:
Europe PubMed Central
Current Topics in Microbiology and Immunology ISBN: 9783540721444
Current Topics in Microbiology and Immunology ISBN: 9783540721444
Monoclonal antibodies are routinely used as therapeutics in a number of disease settings and have thus also been explored as potential treatment for human immunodeficiency virus (HIV)-1 infection. Antibodies targeting viral antigens, and those direct
Autor:
P J Maddon, W C Olson
Publikováno v:
Current drug targets. Infectious disorders. 3(4)
Resistance-testing technology has been incorporated into the standard of care for human immunodeficiency virus type 1 (HIV-1) infection and therapy with protease and reverse transcriptase inhibitors. Inhibitors of HIV-1 entry represent an emerging mo
Autor:
W T, Shearer, R J, Israel, S, Starr, C V, Fletcher, D, Wara, M, Rathore, J, Church, J, DeVille, T, Fenton, B, Graham, P, Samson, S, Staprans, J, McNamara, J, Moye, P J, Maddon, W C, Olson
Publikováno v:
The Journal of infectious diseases. 182(6)
The use of recombinant CD4-IgG2 in pediatric human immunodeficiency virus type 1 (HIV-1) infection was evaluated by single and multidose intravenous infusions in 18 children in a phase 1/2 study. The study drug was well tolerated, and dose proportion
Autor:
D. P. Petrylak, P. W. Kantoff, R. C. Frank, N. D. Shore, Y. Rotshteyn, R. J. Israel, W. C. Olson, T. Ramakrishna, S. Morris
Publikováno v:
Journal of Clinical Oncology. 29:4650-4650
Autor:
S. F. Slovin, S. Morris, M. Kargman, R. Durso, T. Curley, R. J. Israel, W. C. Olson, D. Murphy, H. I. Scher
Publikováno v:
Journal of Clinical Oncology. 29:e15170-e15170
Publikováno v:
Journal of Clinical Oncology. 28:e13534-e13534
e13534 Background: Prostate-specific membrane antigen (PSMA) is an attractive target for antibody-targeted therapy of prostate cancer due to its abundant and selective expression on the surface of ...
Autor:
M L, Alegre, A M, Collins, V L, Pulito, R A, Brosius, W C, Olson, R A, Zivin, R, Knowles, J R, Thistlethwaite, L K, Jolliffe, J A, Bluestone
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 148(11)
The binding specificity of the murine OKT3 has been transferred into a human antibody framework to reduce its immunogenicity. This "humanized" anti-CD3 mAb (gOKT3-5) was previously shown to retain, in vitro, all the properties of native OKT3, includi