Zobrazeno 1 - 10 of 31 pro vyhledávání: '"W C Little"'
1
Acute effects of mildly intoxicating levels of alcohol on left ventricular function in conscious dogs
Autor: W. C. Little, Che Ping Cheng, Zak K. Shihabi
Publikováno v: Journal of Clinical Investigation. 85:1858-1865
We assessed the effect of alcohol, before and after autonomic blockade, on left ventricular (LV) performance in conscious dogs. 10 animals were instrumented to determine LV volume from ultrasonic LV internal dimensions and measure LV pressure with a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848426970074aa18f25b2cc57bc33e19
https://doi.org/10.1172/jci114646
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4
Effects of atrial natriuretic peptide on left ventricular performance in conscious dogs before and after pacing-induced heart failure
Autor: N, Ohte, C P, Cheng, M, Suzuki, W C, Little
Publikováno v: The Journal of pharmacology and experimental therapeutics. 291(2)
Atrial natriuretic peptide (ANP) has potent vasodilatory and natriuretic actions and may have therapeutic benefit in congestive heart failure (CHF). These benefits may be offset by a negative inotropic effect of ANP seen in isolated preparations. How
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6a84c20135afdd0bdf74a6364dd5d1a4
https://pubmed.ncbi.nlm.nih.gov/10525076
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5
Endogenous endothelin-1 depresses left ventricular systolic and diastolic performance in congestive heart failure
Autor: K, Onishi, M, Ohno, W C, Little, C P, Cheng
Publikováno v: The Journal of pharmacology and experimental therapeutics. 288(3)
Endothelin-1 (ET-1) is a positive inotrope in normal hearts; however, the direct cardiac effects of endogenous ET-1 in congestive heart failure (CHF) are unknown. We evaluated the cardiac responses to endogenous ET-1 using an ETA and ETB receptor blo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::76a319d26681ad1767a48d1e3fde6b11
https://pubmed.ncbi.nlm.nih.gov/10027861
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6
The cardiac effects of pimobendan (but not amrinone) are preserved at rest and during exercise in conscious dogs with pacing-induced heart failure
Autor: N, Ohte, C P, Cheng, M, Suzuki, W C, Little
Publikováno v: The Journal of pharmacology and experimental therapeutics. 282(1)
We compared the effects of pimobendan (0.25 mg/kg i.v.), a Ca++ sensitizer, with some phosphodiesterase-III inhibition effects, and amrinone (1 mg/kg plus 10 microg/kg/min i.v.), a PDE-III inhibitor, on left ventricular (LV) systolic and diastolic pe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2b08c1e4dbc9ff699576a2ae551dc391
https://pubmed.ncbi.nlm.nih.gov/9223536
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7
Effects of felodipine on left ventricular systolic and diastolic performance in congestive heart failure
Autor: C P, Cheng, K, Pettersson, W C, Little
Publikováno v: The Journal of pharmacology and experimental therapeutics. 271(3)
We studied the effects of a dihydropyridine calcium blocker, felodipine, on left ventricular (LV) contractile performance and diastolic filling dynamics in conscious dogs with pacing-induced congestive heart failure (CHF) before and after autonomic b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dfb7e6cfe72d57a35c002e2c7f296afe
https://pubmed.ncbi.nlm.nih.gov/7996453
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8
Comparison of effects of dihydropyridine calcium antagonists on left ventricular systolic and diastolic performance
Autor: C P, Cheng, T, Noda, M, Nordlander, M, Ohno, W C, Little
Publikováno v: The Journal of pharmacology and experimental therapeutics. 268(3)
We compared the effects of three dihydropyridine calcium antagonists (felodipine, nifedipine and amlodipine) on left ventricular (LV) contractile performance and diastolic filling dynamics in eight conscious animals. After administering metoprolol an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2d3d067bb520d1a33dac4bd2f9249a4a
https://pubmed.ncbi.nlm.nih.gov/8138936
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9
Should patients with heart disease exercise in the morning or afternoon?
Autor: P M, Murray, D M, Herrington, C W, Pettus, H S, Miller, J D, Cantwell, W C, Little
Publikováno v: Archives of internal medicine. 153(7)
To compare the cardiovascular risk of exercise in the morning and afternoon in patients with established heart disease.Retrospective cohort study.Patients with established heart disease referred for participation in a comprehensive cardiac rehabilita
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::74f81a5810c62c4d7eb48b75837c00dd
https://pubmed.ncbi.nlm.nih.gov/8466373
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10
Effect of felodipine on left ventricular performance in conscious dogs: assessment by left ventricular pressure-volume analysis
Autor: C P, Cheng, Y, Igarashi, K, Pettersson, W C, Little
Publikováno v: The Journal of pharmacology and experimental therapeutics. 257(1)
We assessed the effect of felodipine on left ventricular (LV) performance in 10 healthy, conscious, chronically instrumented dogs, using load-independent measures derived from variably loaded pressure-volume relations. With all reflexes intact, felod
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dbdc06eb69f159dd006a5370138f2b81
https://pubmed.ncbi.nlm.nih.gov/2019984
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