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pro vyhledávání: '"W C, Pickett"'
Autor:
C S Ramesha, W C Pickett
Publikováno v:
Journal of Lipid Research, Vol 28, Iss 3, Pp 326-331 (1987)
Phospholipid fatty acid composition and phospholipid subclass distribution of control and arachidonate-depleted rat polymorphonuclear leukocytes (PMN) were compared. The 20:4-depleted PMN contained significantly higher amounts of 16:1, 18:1 and 20:3
Externí odkaz:
https://doaj.org/article/e71b2db0efaf44558be5758423dd9582
Antiinflammatory and antiarthritic properties of a substituted quinoline carboxylic acid: CL 306,293
Autor:
A E, Sloboda, D, Powell, J F, Poletto, W C, Pickett, J J, Gibbons, D H, Bell, A L, Oronsky, S S, Kerwar
Publikováno v:
The Journal of rheumatology. 18(6)
CL 306,293, a substituted quinoline carboxylic acid at a daily oral dose between 1.5 and 3.0 mg/kg suppressed the inflammation and joint destruction (radiological criteria) associated with both developing and established adjuvant arthritis. When a we
Autor:
W C, Pickett, C S, Ramesha
Publikováno v:
Methods in enzymology. 187
Publikováno v:
American Review of Respiratory Disease. 136:1183-1187
We studied the effect of indomethacin on immunologic mediator release from human bronchial tissue (n = 6) and lung parenchyma (n = 7). Tissues were obtained from surgical specimens, minced, passively sensitized, and challenged with antigen E or anti-
Autor:
W. C. Pickett, Joseph C. Nolan
Publikováno v:
Agents and Actions. 17:73-76
Recent work from this laboratory has shown that macrophages in culture synthesize and secrete a soluble factor(s) that induces the synthesis of collagenase in primary cultures of rabbit chondrocytes (Arth. Rheum. 23, 448, 1980). The current studies w
Publikováno v:
Journal of Applied Physiology. 66:2407-2418
We studied lung vascular injury and quantitated lung eicosanoids in rats after intraperitoneal injection of Salmonella enteritidis endotoxin. Within 40 min after endotoxin injection (20 mg/kg), lung tissue thromboxane B2 doubled, although 6-ketoprost
Autor:
C S Ramesha, W C Pickett
Publikováno v:
The Journal of Immunology. 138:1559-1563
The molecular heterogeneity of platelet-activating factor (PAF) synthesized by unstimulated and Ca2+ ionophore (A23187)-stimulated PMN from rat, mouse, and guinea pig and by rat basophilic leukemia (RBL) cells was investigated by gas chromatography-n
Autor:
E J Goetzl, W C Pickett
Publikováno v:
The Journal of experimental medicine, vol 153, iss 2
The Journal of Experimental Medicine
The Journal of Experimental Medicine
A specific 5(S),12(R)-dihydroxy-eicosa-6,8,10(trans/trans/cis), 14(cis)-tetraenoic acid, designated leukotriene B, is generated by the lipoxygenation and subsequent enzymatic hydration of arachidonic acid in a variety of leukocytes. Leukotriene B eli
Autor:
W C Pickett, C S Ramesha
Publikováno v:
Journal of Biological Chemistry. 261:7592-7595
Rat peripheral or elicited polymorphonuclear leukocytes 90% deficient in arachidonic acid incorporate, after stimulation with the calcium ionophore A23187, 86% less acetate into platelet-activating factor than control. The total amount of platelet-ac
Autor:
W C Pickett, C S Ramesha
Publikováno v:
Journal of Lipid Research, Vol 28, Iss 3, Pp 326-331 (1987)
Phospholipid fatty acid composition and phospholipid subclass distribution of control and arachidonate-depleted rat polymorphonuclear leukocytes (PMN) were compared. The 20:4-depleted PMN contained significantly higher amounts of 16:1, 18:1 and 20:3