Zobrazeno 1 - 10
of 31
pro vyhledávání: '"W C, Little"'
Publikováno v:
Journal of Clinical Investigation. 85:1858-1865
We assessed the effect of alcohol, before and after autonomic blockade, on left ventricular (LV) performance in conscious dogs. 10 animals were instrumented to determine LV volume from ultrasonic LV internal dimensions and measure LV pressure with a
Autor:
W C Little
Publikováno v:
Circulation. 85:2326-2328
Autor:
J W, Hirshfeld, J S, Banas, B H, Brundage, M, Cowley, G J, Dehmer, S G, Ellis, G A, Ewy, D P, Faxon, D R, Holmes, A K, Jacobs, W C, Little, R D, Magorien, M A, Nocero, S, Oesterle, C J, Pepine, M, Taubman, C, Tommaso, R E, Vlietstra, R, Vogel, J S, Forrester, P S, Douglas, J D, Fischer, G, Gregoratos, M J, Wolk
Publikováno v:
Journal of the American College of Cardiology. 34(7)
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 291(2)
Atrial natriuretic peptide (ANP) has potent vasodilatory and natriuretic actions and may have therapeutic benefit in congestive heart failure (CHF). These benefits may be offset by a negative inotropic effect of ANP seen in isolated preparations. How
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 288(3)
Endothelin-1 (ET-1) is a positive inotrope in normal hearts; however, the direct cardiac effects of endogenous ET-1 in congestive heart failure (CHF) are unknown. We evaluated the cardiac responses to endogenous ET-1 using an ETA and ETB receptor blo
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 282(1)
We compared the effects of pimobendan (0.25 mg/kg i.v.), a Ca++ sensitizer, with some phosphodiesterase-III inhibition effects, and amrinone (1 mg/kg plus 10 microg/kg/min i.v.), a PDE-III inhibitor, on left ventricular (LV) systolic and diastolic pe
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 271(3)
We studied the effects of a dihydropyridine calcium blocker, felodipine, on left ventricular (LV) contractile performance and diastolic filling dynamics in conscious dogs with pacing-induced congestive heart failure (CHF) before and after autonomic b
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 268(3)
We compared the effects of three dihydropyridine calcium antagonists (felodipine, nifedipine and amlodipine) on left ventricular (LV) contractile performance and diastolic filling dynamics in eight conscious animals. After administering metoprolol an
Publikováno v:
Archives of internal medicine. 153(7)
To compare the cardiovascular risk of exercise in the morning and afternoon in patients with established heart disease.Retrospective cohort study.Patients with established heart disease referred for participation in a comprehensive cardiac rehabilita
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 257(1)
We assessed the effect of felodipine on left ventricular (LV) performance in 10 healthy, conscious, chronically instrumented dogs, using load-independent measures derived from variably loaded pressure-volume relations. With all reflexes intact, felod