Zobrazeno 1 - 10
of 344
pro vyhledávání: '"W C, Hubbard"'
Autor:
M. A. Zouache, B. T. Richards, C. M. Pappas, R. A. Anstadt, J. Liu, T. Corsetti, S. Matthews, N. A. Seager, S. Schmitz-Valckenberg, M. Fleckenstein, W. C. Hubbard, J. Thomas, J. L. Hageman, B. L. Williams, G. S. Hageman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Dysregulation of the alternative pathway (AP) of the complement system is a significant contributor to age-related macular degeneration (AMD), a primary cause of irreversible vision loss worldwide. Here, we assess the contribution of the liv
Externí odkaz:
https://doaj.org/article/5509274071cb4770a0b493d6e99eb582
Autor:
Edward J. Fuchs, Charles Flexner, R C Garner, Lawrence S. Lee, Teresa L. Parsons, Courtney V. Fletcher, Jianmeng Chen, G E Pakes, M Seymour, W C Hubbard
Publikováno v:
Clinical Pharmacology & Therapeutics. 88:796-800
Accelerator mass spectrometry (AMS) is an ultrasensitive technique to detect radiolabeled compounds. We administered a microdose (100 µg) of 14C-labeled zidovudine (ZDV) with or without a standard unlabeled dose (300 mg) to healthy volunteers. Intra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::427eda343e4bbcf673dd1fb98c4fd3b5
https://doi.org/10.1038/clpt.2010.188
https://doi.org/10.1038/clpt.2010.188
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 18:35-39
3Alpha,5beta-Tetrahydrocortisol (THF) was administered topically and intracamerally to ocular normotensive cynomolgus monkeys to determine whether it affects outflow facility. Monkeys received THF either topically at a dose of 2 x 5 microl drops of 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::602a8dff25175da815cd4b847b5e375b
https://doi.org/10.1089/108076802317233199
https://doi.org/10.1089/108076802317233199
Autor:
M. WAGENMANN, F. M. BAROODY, M. DESROSIERS, W. C. HUBBARD, S. FORD, L. M. LICHTENSTEIN, R. M. NACLERIO
Publikováno v:
Clinical Experimental Allergy. 26:371-378
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3058d69372dc40e64e8d2c58676f1bb5
https://doi.org/10.1046/j.1365-2222.1996.d01-324.x
https://doi.org/10.1046/j.1365-2222.1996.d01-324.x
Autor:
W J Burman, W C Hubbard, Susan E. Dorman, M T Melia, E J Fuchs, Eric L. Nuermberger, Yanhui Lu, Kelly E. Dooley, Erin Bliven-Sizemore, Michael Weiner
Publikováno v:
Clinical pharmacology and therapeutics. 91(5)
Rifapentine (RP T) is an antituberculosis drug that may shorten treatment duration when substituted for rifampin (RI F).The maximal tolerated daily dose of RP T and its potential for cytochrome 3A4 induction and autoinduction at clinically relevant d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::130b87a166fa3b2da0bd547359e4cb30
https://pubmed.ncbi.nlm.nih.gov/22472995
https://pubmed.ncbi.nlm.nih.gov/22472995
Autor:
D W MacGlashan, W C Hubbard
Publikováno v:
The Journal of Immunology. 151:6358-6369
IL-3 is known to enhance the secretion of several mediators from human basophils activated by receptor-mediated stimuli. IL-3 can cause a qualitative change in the mediator release pattern for C5a-mediated stimulation; without IL-3, C5a causes no leu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b695a89173c46d4703ef3a46641d4f6a
https://doi.org/10.4049/jimmunol.151.11.6358
https://doi.org/10.4049/jimmunol.151.11.6358
Publikováno v:
Journal of Applied Physiology. 75:1110-1116
To elucidate the mechanism of calcium chelator-induced airway constriction, we examined the relationship between prostanoids and histamine in bronchoalveolar lavage (BAL) fluid and the magnitude of airway constriction in peripheral airways of anesthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3e5b8b51594660f43924569bc96b0a
https://doi.org/10.1152/jappl.1993.75.3.1110
https://doi.org/10.1152/jappl.1993.75.3.1110
Autor:
W A Massey, C B Guo, A M Dvorak, W C Hubbard, B S Bhagavan, V L Cohan, J A Warner, A Kagey-Sobotka, L M Lichtenstein
Publikováno v:
The Journal of Immunology. 147:1621-1627
As part of an ongoing investigation of human mast cell heterogeneity, we have isolated, partially purified, and characterized the uterine mast cell and compared it with mast cells isolated from other organs. The average histamine content of myometriu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::205b49cf1a81bac260bea31acc20c999
https://doi.org/10.4049/jimmunol.147.5.1621
https://doi.org/10.4049/jimmunol.147.5.1621
Publikováno v:
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. 18(1)
3Alpha,5beta-Tetrahydrocortisol (THF) was administered topically and intracamerally to ocular normotensive cynomolgus monkeys to determine whether it affects outflow facility. Monkeys received THF either topically at a dose of 2 x 5 microl drops of 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c1d4aedf7b34316f3ef7e0e0df3adeee
https://pubmed.ncbi.nlm.nih.gov/11858613
https://pubmed.ncbi.nlm.nih.gov/11858613
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 30(9)
Several studies suggest that endogenous glucocorticoids can dampen the severity of experimental allergic reactions in animals.To investigate the influence that endogenous glucocorticoids have on the course of IgE-mediated pulmonary early and late pha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c24489556179b42dad4bd6e70f4c9ae8
https://pubmed.ncbi.nlm.nih.gov/10971472
https://pubmed.ncbi.nlm.nih.gov/10971472