Zobrazeno 1 - 8
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pro vyhledávání: '"W C, Duivenvoorden"'
Publikováno v:
Clinicalexperimental metastasis. 18(6)
Matrix metalloproteinases (MMPs) are essential in several stages of the metastatic process, and in normal bone development and remodeling. We explored whether the interaction between tumor cells and bone leads to changes in MMP and tissue inhibitor o
Publikováno v:
International journal of cancer. 91(6)
The expression of matrix metalloproteinases (MMPs) is often associated with invasiveness or grade of tumours. Increased blood levels of MMP proteins, including MMP-1, MMP-2, MMP-3 and MMP-9 have been detected in various types of cancers. With the exc
Publikováno v:
Cancer. 88
This review summarizes evidence that the formation of bone metastases is the result of multiple synergistic cellular and molecular interactions between metastatic cells and the unique microenvironment in bone.Molecular technologies have been used to
Publikováno v:
Critical Reviews in Eukaryotic Gene Expression. 10
Bone metastases occur in approximately 80% of patients with advanced cancer. They are characterized by cancer cell growth and bone destruction that cause pain, fractures, anemia, and hypercalcemia. At diagnosis, bone metastases are usually incurable
Publikováno v:
Clinicalexperimental metastasis. 17(1)
Bone metastases are a common complication in prostate and breast cancer patients. It leads to extensive morbidity and eventually mortality. Matrix metalloproteinases (MMPs) are known to be involved in the metastatic process. MMP activity can be down-
Publikováno v:
Invasionmetastasis. 17(6)
Bone metastases are a common complication in prostate and breast cancer patients. It leads to extensive morbidity and eventually mortality. Matrix metalloproteinases are implicated in various steps of development of metastasis, through their ability
Autor:
W C, Duivenvoorden, P, Maier
Publikováno v:
European journal of cell biology. 64(2)
The transition of quiescent freshly isolated rat hepatocytes (G0 phase) into a prereplicative stage of the cell cycle (G1 phase) has been visualized by a decrease in fluorescence of quinacrine dihydrochloride (QDH)-stained nuclei. This transition mig
Publikováno v:
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology. 4(2)
The phenobarbital induced shift from G0 to G1 cell cycle phases was analyzed in freshly isolated cultured rat hepatocytes by image analysis. Nuclei in situ in monolayers or in an isolated state were stained with quinacrine dihydrochloride. Fluorescen