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Heat-induced testicular apoptosis occurs independently of hormonal depletion

Autor: Y, Yin, B C, Stahl, W C, DeWolf, A, Morgentaler

Publikováno v: Apoptosis : an international journal on programmed cell death. 3(4)

Previous studies have demonstrated that testicular germ cell apoptosis can be induced both by heat stress and by withdrawal of androgens and gonadotrophins. To investigate whether heat-induced germ cell apoptosis occurs independently of the altered l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3009d3908c6e5d890e767256cbd0bc14
https://pubmed.ncbi.nlm.nih.gov/14646492

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Salvage intravesical therapy with interferon-alpha 2b plus low dose bacillus Calmette-Guerin is effective in patients with superficial bladder cancer in whom bacillus Calmette-Guerin alone previously failed

Autor: M A, O'Donnell, J, Krohn, W C, DeWolf

Publikováno v: The Journal of urology. 166(4)

We determined whether combining low dose bacillus Calmette-Guerin (BCG) interferon-alpha 2B would be effective for patients in whom previous BCG failed.A total of 40 patients in whom 1 (19) or more (21) previous induction courses of BCG failed receiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f3fe42d35b963a85998a360817b9acfd
https://pubmed.ncbi.nlm.nih.gov/11547062

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Early catheter removal in 100 consecutive patients undergoing radical retropubic prostatectomy

Autor: W F, Santis, M A, Hoffman, W C, Dewolf

Publikováno v: BJU international. 85(9)

To investigate the outcome of 100 consecutive patients selected for early catheter removal after radical retropubic prostatectomy (RRP), where urethral catheter drainage is used routinely for 2-3 weeks.The study included 129 consecutive patients with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1274065e74edc8851d913e3e815a5e88
https://pubmed.ncbi.nlm.nih.gov/10848696

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Clinical and pathological characteristics of micropapillary transitional cell carcinoma: a highly aggressive variant

Autor: J K, Maranchie, B T, Bouyounes, P L, Zhang, M A, O'Donnell, I C, Summerhayes, W C, DeWolf

Publikováno v: The Journal of urology. 163(3)

We present preliminary clinical, histochemical and molecular findings for 5 patients with micropapillary transitional cell carcinoma of the bladder, a rare histological variant not widely recognized in the urological literature.The 5 patients were pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::130883bd66163d6f8931e7485e40b665
https://pubmed.ncbi.nlm.nih.gov/10687969

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IFN-alpha 2B enhances Th1 cytokine responses in bladder cancer patients receiving Mycobacterium bovis bacillus Calmette-Guérin immunotherapy

Autor: Y, Luo, X, Chen, T M, Downs, W C, DeWolf, M A, O'Donnell

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 162(4)

Combination therapy with intravesical bacillus Calmette-Guérin (BCG) plus IFN-alpha for superficial bladder cancer has been demonstrated to be more effective than either single agent alone in animal studies and of suggested greater efficacy in clini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6a73ea9eb5a0e3de041b5a8720715374
https://pubmed.ncbi.nlm.nih.gov/9973521

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Temperature-mediated germ cell loss in the testis is associated with altered expression of the cell-cycle regulator p53

Autor: S A, Socher, Y, Yin, W C, Dewolf, A, Morgentaler

Publikováno v: The Journal of urology. 157(5)

The dependence of spermatogenesis on the relatively cool environment of the scrotum is well known, and recent work has shown that germ cells undergo apoptosis upon exposure to abdominal temperature. p53 is a potent inducer of apoptosis and regulator

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ebc61849647bed3941d006d00c1e57d6
https://pubmed.ncbi.nlm.nih.gov/9112577

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Heat stress causes testicular germ cell apoptosis in adult mice

Autor: Y, Yin, K L, Hawkins, W C, DeWolf, A, Morgentaler

Publikováno v: Journal of andrology. 18(2)

An investigation was undertaken to determine whether the germ-cell loss associated with exposure of the testis to abdominal temperature occurs by apoptosis. Using an adult-mouse model of experimental unilateral cryptorchidism, it was observed that DN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::45654e79aa536ff97dc81ffa4fd507c0
https://pubmed.ncbi.nlm.nih.gov/9154510

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Occult prostate cancer in men with low serum testosterone levels

Autor: A, Morgentaler, C O, Bruning, W C, DeWolf

Publikováno v: JAMA. 276(23)

To determine the prevalence of occult prostate cancer in men with low serum total testosterone or free testosterone levels.Retrospective analysis of a consecutive series of men.Academic teaching hospital.Seventy-seven men with low total testosterone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9103c496b0bf8fb2f416a3c89822159d
https://pubmed.ncbi.nlm.nih.gov/8968017

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